Bioreporters and biosensors for arsenic detection. Biotechnological solutions for a world-wide pollution problem.

A wide variety of whole cell bioreporter and biosensor assays for arsenic detection has been developed over the past decade. The assays permit flexible detection instrumentation while maintaining excellent method of detection limits in the environmentally relevant range of 10-50 μg arsenite per L and below. New emerging trends focus on genetic rewiring of reporter cells and/or integration into microdevices for more optimal detection. A number of case studies have shown realistic field applicability of bioreporter assays.

[1]  S. Baumberg,et al.  Resistance to Arsenic Compounds Conferred by a Plasmid Transmissible Between Strains of Escherichia coli , 1973, Journal of bacteriology.

[2]  M. J. Arcos-Martínez,et al.  Development of acid phosphatase based amperometric biosensors for the inhibitive determination of As(V). , 2012, Talanta.

[3]  G. Church,et al.  Synthetic Gene Networks That Count , 2009, Science.

[4]  P. Bertin,et al.  Arsenic in contaminated waters: biogeochemical cycle, microbial metabolism and biotreatment processes. , 2009, Biochimie.

[5]  C. Steinmaus,et al.  Evaluation of two new arsenic field test kits capable of detecting arsenic water concentrations close to 10 microg/L. , 2006, Environmental science & technology.

[6]  P. Viswanath Evaluation of certain contaminants in food (Seventy-second report of the Joint FAO/WHO Expert Committee on Food Additives) , 2012 .

[7]  Li Li,et al.  Construction of WCB-11: a novel phiYFP arsenic-resistant whole-cell biosensor. , 2010, Journal of environmental sciences.

[8]  Evaluation of Two New Arsenic Field Test Kits Capable of Detecting Arsenic Water Concentrations Close to 10 μ , 2006 .

[9]  J. Matschullat Arsenic in the geosphere--a review. , 2000, The Science of the total environment.

[10]  Yong-guan Zhu,et al.  A Novel Biosensor Selective for Organoarsenicals , 2012, Applied and Environmental Microbiology.

[11]  Rajeev J Ram,et al.  Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture. , 2011, Lab on a chip.

[12]  X. Fuku,et al.  Cytochrome c biosensor for determination of trace levels of cyanide and arsenic compounds. , 2012, Analytica chimica acta.

[13]  Gerardo Perozziello,et al.  Microchemostat-microbial continuous culture in a polymer-based, instrumented microbioreactor. , 2006, Lab on a chip.

[14]  Barry Rosen,et al.  A 3D localized surface plasmon resonance biosensor for the study of trivalent arsenic binding to the ArsA ATPase. , 2012, Biosensors & bioelectronics.

[15]  Sylvia Daunert,et al.  Construction of spores for portable bacterial whole-cell biosensing systems. , 2007, Analytical chemistry.

[16]  Pascal Colpo,et al.  A printed nanolitre-scale bacterial sensor array. , 2011, Lab on a chip.

[17]  Jan Roelof van der Meer,et al.  Analysis of bioavailable arsenic in rice with whole cell living bioreporter bacteria. , 2007, Journal of agricultural and food chemistry.

[18]  Kazuyuki Yoshida,et al.  Monitoring of environmental arsenic by cultures of the photosynthetic bacterial sensor illuminated with a near-infrared light emitting diode array. , 2011, Journal of microbiology and biotechnology.

[19]  Koichi Inoue,et al.  Sensitive fluorescent microplate bioassay using recombinant Escherichia coli with multiple promoter-reporter units in tandem for detection of arsenic. , 2009, Journal of bioscience and bioengineering.

[20]  Michael Berg,et al.  Bacterial bioassay for rapid and accurate analysis of arsenic in highly variable groundwater samples. , 2005, Environmental science & technology.

[21]  Scott Fendorf,et al.  Spatial and Temporal Variations of Groundwater Arsenic in South and Southeast Asia , 2010, Science.

[22]  S. Quake,et al.  Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat , 2005, Science.

[23]  B. Rosen,et al.  Genetic mapping of the interface between the ArsD metallochaperone and the ArsA ATPase , 2011, Molecular microbiology.

[24]  Alex Groisman,et al.  A microfluidic chemostat for experiments with bacterial and yeast cells , 2005, Nature Methods.

[25]  Olga Domínguez-Renedo,et al.  Immobilization of Acetylcholinesterase on Screen-Printed Electrodes. Application to the Determination of Arsenic(III) , 2010, Sensors.

[26]  M Mergeay,et al.  luxAB gene fusions with the arsenic and cadmium resistance operons of Staphylococcus aureus plasmid pI258. , 1993, FEMS microbiology letters.

[27]  Masuo Kondoh,et al.  Whole-cell arsenite biosensor using photosynthetic bacterium Rhodovulum sulfidophilum , 2006, Applied Microbiology and Biotechnology.

[28]  Sylvia Daunert,et al.  Integration of spore-based genetically engineered whole-cell sensing systems into portable centrifugal microfluidic platforms , 2010, Analytical and bioanalytical chemistry.

[29]  Hauke Harms,et al.  Internal arsenite bioassay calibration using multiple bioreporter cell lines , 2007, Microbial biotechnology.

[30]  Jan Roelof van der Meer,et al.  Miniaturized bacterial biosensor system for arsenic detection holds great promise for making integrated measurement device , 2011, Bioengineered bugs.

[31]  Mohammad Sohel Rahman,et al.  Effectiveness and reliability of arsenic field testing kits: are the million dollar screening projects effective or not? , 2002, Environmental science & technology.

[32]  L. Tsimring,et al.  A synchronized quorum of genetic clocks , 2009, Nature.

[33]  Baojun Wang,et al.  Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology , 2011, Nature communications.

[34]  Shimshon Belkin,et al.  Microbial sensor cell arrays. , 2012, Current opinion in biotechnology.

[35]  S. Belkin,et al.  Where microbiology meets microengineering: design and applications of reporter bacteria , 2010, Nature Reviews Microbiology.

[36]  Mohammad Shohel Rana Siddiki,et al.  Solid Phase Biosensors for Arsenic or Cadmium Composed of A trans Factor and cis Element Complex , 2011, Sensors.

[37]  S. Silver,et al.  Energy-dependent arsenate efflux: the mechanism of plasmid-mediated resistance. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[38]  Jan Roelof van der Meer,et al.  Ultrasensitive reporter protein detection in genetically engineered bacteria. , 2005, Analytical chemistry.

[39]  D. Nordstrom Worldwide Occurrences of Arsenic in Ground Water , 2002, Science.

[40]  Hauke Harms,et al.  Field testing of arsenic in groundwater samples of Bangladesh using a test kit based on lyophilized bioreporter bacteria. , 2012, Environmental science & technology.

[41]  M Virta,et al.  Recombinant luminescent bacteria for measuring bioavailable arsenite and antimonite , 1997, Applied and environmental microbiology.

[42]  J. Wu,et al.  Metalloregulated expression of the ars operon. , 1993, The Journal of biological chemistry.

[43]  Baojun Wang,et al.  Customizing cell signaling using engineered genetic logic circuits. , 2012, Trends in microbiology.

[44]  Jan Roelof van der Meer,et al.  Development of a set of simple bacterial biosensors for quantitative and rapid measurements of arsenite and arsenate in potable water. , 2003, Environmental science & technology.

[45]  S. Daunert,et al.  Genetically engineered bacteria: electrochemical sensing systems for antimonite and arsenite. , 1997, Analytical chemistry.

[46]  Ivan Razinkov,et al.  Sensing array of radically coupled genetic biopixels , 2011, Nature.

[47]  D. G. Guha Mazumder Arsenic exposure and health effects. , 2002, Journal of toxicology. Clinical toxicology.

[48]  G. Minasov,et al.  Crystal structure of an apo form of Shigella flexneri ArsH protein with an NADPH‐dependent FMN reductase activity , 2007, Protein science : a publication of the Protein Society.

[49]  K. Jensen,et al.  In situ measurement of bioluminescence and fluorescence in an integrated microbioreactor. , 2006, Biotechnology and bioengineering.

[50]  Alistair Elfick,et al.  A pH-based biosensor for detection of arsenic in drinking water , 2011, Analytical and bioanalytical chemistry.

[51]  B. Gibbs,et al.  Role of Aspergillus niger acrA in Arsenic Resistance and Its Use as the Basis for an Arsenic Biosensor , 2012, Applied and Environmental Microbiology.

[52]  S. Daunert,et al.  Sensing antimonite and arsenite at the subattomole level with genetically engineered bioluminescent bacteria. , 1997, Analytical chemistry.

[53]  C. Saltikov,et al.  The ArsR Repressor Mediates Arsenite-Dependent Regulation of Arsenate Respiration and Detoxification Operons of Shewanella sp. Strain ANA-3 , 2009, Journal of bacteriology.

[54]  G. Barrett,et al.  Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes. , 2000, Chemical reviews.

[55]  Gérald Thouand,et al.  Improvement of the identification of four heavy metals in environmental samples by using predictive decision tree models coupled with a set of five bioluminescent bacteria. , 2011, Environmental science & technology.

[56]  Chris French,et al.  Modeling the arsenic biosensor system , 2007, BMC Systems Biology.

[57]  S. Silver,et al.  A bacterial view of the periodic table: genes and proteins for toxic inorganic ions , 2005, Journal of Industrial Microbiology and Biotechnology.

[58]  Robert S. Marks,et al.  UV and arsenate toxicity: a specific and sensitive yeast bioluminescence assay , 2011, Cell Biology and Toxicology.

[59]  Yosi Shacham-Diamand,et al.  Online monitoring of water toxicity by use of bioluminescent reporter bacterial biochips. , 2011, Environmental science & technology.

[60]  B. Erickson Field kits fail to provide accurate measure of arsenic in groundwater. , 2003, Environmental science & technology.

[61]  Jan Roelof van der Meer,et al.  Development of a microfluidics biosensor for agarose-bead immobilized Escherichia coli bioreporter cells for arsenite detection in aqueous samples. , 2011, Lab on a chip.

[62]  M. Dubow,et al.  An Escherichia coli chromosomal ars operon homolog is functional in arsenic detoxification and is conserved in gram-negative bacteria , 1995, Journal of bacteriology.

[63]  Kazuyuki Yoshida,et al.  Application of fluorescent protein-tagged trans factors and immobilized cis elements to monitoring of toxic metals based on in vitro protein-DNA interactions. , 2010, Biosensors & bioelectronics.

[64]  M. Elowitz,et al.  A synthetic oscillatory network of transcriptional regulators , 2000, Nature.