A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity

[1]  C. Overall,et al.  Absolute proteomic quantification of the activity state of proteases and proteolytic cleavages using proteolytic signature peptides and isobaric tags. , 2014, Journal of proteomics.

[2]  A. Dufour,et al.  Missing the target: matrix metalloproteinase antitargets in inflammation and cancer. , 2013, Trends in pharmacological sciences.

[3]  Christopher M. Overall,et al.  CLIPPER: an add-on to the Trans-Proteomic Pipeline for the automated analysis of TAILS N-terminomics data , 2012, Biological chemistry.

[4]  S. Weiss,et al.  MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function. , 2012, Genes & development.

[5]  E. Fish,et al.  The yin and yang of viruses and interferons , 2012, Trends in Immunology.

[6]  Christopher M Overall,et al.  Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates , 2011, Nature Protocols.

[7]  F. Beau,et al.  A Selective Matrix Metalloproteinase-12 Inhibitor Retards Atherosclerotic Plaque Development in Apolipoprotein E–Knockout Mice , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[8]  Farshid S. Garmaroudi,et al.  Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection , 2010, Proceedings of the National Academy of Sciences.

[9]  F. Belardelli,et al.  Recent advances on the immunomodulatory effects of IFN-α: Implications for cancer immunotherapy and autoimmunity , 2010, Autoimmunity.

[10]  Christopher M. Overall,et al.  A Statistics-based Platform for Quantitative N-terminome Analysis and Identification of Protease Cleavage Products* , 2010, Molecular & Cellular Proteomics.

[11]  C. Overall,et al.  Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics* , 2010, Molecular & Cellular Proteomics.

[12]  Natalie I. Tasman,et al.  A guided tour of the Trans‐Proteomic Pipeline , 2010, Proteomics.

[13]  L. Foster,et al.  Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products , 2010, Nature Biotechnology.

[14]  Patrick G. A. Pedrioli Trans-Proteomic Pipeline: A Pipeline for Proteomic Analysis , 2010, Proteome Bioinformatics.

[15]  Christopher M. Overall,et al.  Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting , 2009, Nature Reviews Drug Discovery.

[16]  C. Overall,et al.  Matrix metalloproteinase proteomics: substrates, targets, and therapy. , 2009, Current opinion in cell biology.

[17]  A. M. Houghton,et al.  Macrophage elastase kills bacteria within murine macrophages , 2009, Nature.

[18]  Jie Huang,et al.  The IκBα gene is a peroxisome proliferator‐activated receptor cardiac target gene , 2009, The FEBS journal.

[19]  A. Lopez-Campistrous,et al.  Matrix Metalloproteinase-7 and ADAM-12 (a Disintegrin and Metalloproteinase-12) Define a Signaling Axis in Agonist-Induced Hypertension and Cardiac Hypertrophy , 2009, Circulation.

[20]  M. Karin,et al.  Regulation and function of NF-kappaB transcription factors in the immune system. , 2009, Annual review of immunology.

[21]  C. Overall,et al.  Chapter 13. Characterizing proteolytic processing of chemokines by mass spectrometry, biochemistry, neo-epitope antibodies and functional assays. , 2009, Methods in enzymology.

[22]  J. Edwards,et al.  Exploring the full spectrum of macrophage activation , 2008, Nature Reviews Immunology.

[23]  C. Overall,et al.  Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx. , 2008, Blood.

[24]  B. McManus,et al.  Ablation of Matrix Metalloproteinase-9 Increases Severity of Viral Myocarditis in Mice , 2008, Circulation.

[25]  Allen D. Delaney,et al.  Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing , 2007, Nature Methods.

[26]  A. M. Houghton,et al.  Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. , 2006, Cancer research.

[27]  Enqi Liu,et al.  Macrophage Metalloelastase Accelerates the Progression of Atherosclerosis in Transgenic Rabbits , 2006, Circulation.

[28]  Philippe Cuniasse,et al.  Development of Selective Inhibitors and Substrate of Matrix Metalloproteinase-12* , 2006, Journal of Biological Chemistry.

[29]  Christopher M. Overall,et al.  Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy , 2006, Nature Reviews Cancer.

[30]  Christopher M Overall,et al.  Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. , 2006, Nature reviews. Cancer.

[31]  R. Garofalo,et al.  Human Metapneumovirus Induces a Profile of Lung Cytokines Distinct from That of Respiratory Syncytial Virus , 2005, Journal of Virology.

[32]  William C. Parks,et al.  Matrix metalloproteinases as modulators of inflammation and innate immunity , 2004, Nature Reviews Immunology.

[33]  J. Everitt,et al.  Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[34]  M. Belvisi,et al.  The role of matrix metalloproteinases (MMPs) in the pathophysiology of chronic obstructive pulmonary disease (COPD): a therapeutic role for inhibitors of MMPs? , 2003, Inflammation Research.

[35]  Alexey I Nesvizhskii,et al.  Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. , 2002, Analytical chemistry.

[36]  C. Samuel,et al.  Antiviral Actions of Interferons , 2001, Clinical Microbiology Reviews.

[37]  C. Overall,et al.  Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. , 2000, Science.

[38]  Mark D. Huffman,et al.  Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. , 1998, The Journal of clinical investigation.

[39]  E. Yukawa,et al.  Chronopharmacological Study of Interferon-α in Mice , 1997 .

[40]  E. Yukawa,et al.  Chronopharmacological study of interferon-alpha in mice. , 1997, The Journal of pharmacology and experimental therapeutics.

[41]  T. Ley,et al.  Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. , 1993, The Journal of biological chemistry.

[42]  B. Benacerraf,et al.  Blood clearance of P32-labeled vesicular stomatitis and Newcastle disease viruses by the reticuloendothelial system in mice. , 1960, Journal of immunology.