Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

[1]  G J Letchworth,et al.  Vesicular stomatitis. , 1999, Veterinary journal.

[2]  G. Coukos,et al.  Use of carrier cells to deliver a replication-selective herpes simplex virus-1 mutant for the intraperitoneal therapy of epithelial ovarian cancer. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[3]  F. Burke.  Cytokines (IFNs, TNF-alpha, IL-2 and IL-12) and animal models of cancer. , 1999, Cytokines, cellular & molecular therapy.

[4]  A. Hengstermann,et al.  Replication of ONYX-015, a Potential Anticancer Adenovirus, Is Independent of p53 Status in Tumor Cells , 1998, Journal of Virology.

[5]  B. Roizman,et al.  The Herpes Simplex Virus US11 Protein Effectively Compensates for the γ134.5 Gene if Present before Activation of Protein Kinase R by Precluding Its Phosphorylation and That of the α Subunit of Eukaryotic Translation Initiation Factor 2 , 1998, Journal of Virology.

[6]  H. Kawasaki,et al.  Aberrant expression of double-stranded RNA-dependent protein kinase in hepatocytes of chronic hepatitis and differentiated hepatocellular carcinoma. , 1998, Cancer research.

[7]  G. Stark,et al.  How cells respond to interferons. , 1998, Annual review of biochemistry.

[8]  M. Coffey,et al.  The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus , 1998, The EMBO journal.

[9]  L. Platanias,et al.  Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression. , 1998, Blood.

[10]  P. Hersey,et al.  Interferon-resistant Human Melanoma Cells Are Deficient in ISGF3 Components, STAT1, STAT2, and p48-ISGF3γ* , 1997, The Journal of Biological Chemistry.

[11]  J. Christensen,et al.  Cooperation of B cells and T cells is required for survival of mice infected with vesicular stomatitis virus. , 1997, International immunology.

[12]  F. Garrido,et al.  Characterization of a gastric tumor cell line defective in MHC class I inducibility by both α- and γ-interferon , 1996 .

[13]  F. Garrido,et al.  Characterization of a gastric tumor cell line defective in MHC class I inducibility by both alpha- and gamma-interferon. , 1996, Tissue Antigens.

[14]  M. Peeples,et al.  Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy. , 1994, Cancer research.

[15]  M. Peeples,et al.  Complete regression of human neuroblastoma xenografts in athymic mice after local Newcastle disease virus therapy. , 1994, Journal of the National Cancer Institute.

[16]  D. Grandér,et al.  Primary leukemia cells resistant to alpha-interferon in vitro are defective in the activation of the DNA-binding factor interferon-stimulated gene factor 3. , 1994, Blood.

[17]  C. Aoki,et al.  Central neuropathogenesis of vesicular stomatitis virus infection of immunodeficient mice , 1993, Journal of virology.

[18]  L. Platanias,et al.  Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system. , 1992, Blood.

[19]  N. Niederle,et al.  Development and mechanisms of interferon resistance. , 1990, Cancer treatment reviews.

[20]  G. Sen,et al.  Inhibition of vesicular stomatitis viral mRNA synthesis by interferons , 1987, Journal of virology.

[21]  D. Cave,et al.  Defective interfering virus particles modulate virulence , 1985, Journal of virology.

[22]  R. Huebner,et al.  Studies on the use of viruses in the treatment of carcinoma of the cervix , 1956 .