Protein Translocation Assays to Probe Protease Function and Screen for Inhibitors.

[1]  O. Schilling,et al.  Taspase1: a 'misunderstood' protease with translational cancer relevance , 2016, Oncogene.

[2]  C. García-echeverría,et al.  Inhibitors of the p53/hdm2 protein-protein interaction-path to the clinic. , 2013, Bioorganic & medicinal chemistry letters.

[3]  C. Ottmann,et al.  Allosteric inhibition of Taspase1′s pathobiological activity by enforced dimerization in vivo , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  Asher Mullard,et al.  Protein–protein interaction inhibitors get into the groove , 2012, Nature Reviews Drug Discovery.

[5]  G. Schneider,et al.  Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors , 2011, PloS one.

[6]  R. Huber,et al.  HTRA proteases: regulated proteolysis in protein quality control , 2011, Nature Reviews Molecular Cell Biology.

[7]  R. Marschalek,et al.  Cell-based Analysis of Structure-Function Activity of Threonine Aspartase 1* , 2010, The Journal of Biological Chemistry.

[8]  D. L. Taylor,et al.  Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2. , 2010, Assay and drug development technologies.

[9]  C. Ottmann,et al.  Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions. , 2010, Angewandte Chemie.

[10]  Ozlem Keskin,et al.  Human Cancer Protein-Protein Interaction Network: A Structural Perspective , 2009, PLoS Comput. Biol..

[11]  Jens P. von Kries,et al.  Translocation Biosensors – Cellular System Integrators to Dissect CRM1-Dependent Nuclear Export by Chemicogenomics , 2009, Sensors.

[12]  Michelle R Arkin,et al.  The road less traveled: modulating signal transduction enzymes by inhibiting their protein-protein interactions. , 2009, Current opinion in chemical biology.

[13]  C. Ottmann,et al.  A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A. , 2009, Journal of molecular biology.

[14]  Sara Linse,et al.  Methods for the detection and analysis of protein–protein interactions , 2007, Proteomics.

[15]  B. Turk.  Targeting proteases: successes, failures and future prospects , 2006, Nature Reviews Drug Discovery.

[16]  S. Gulnik,et al.  Analysis of intracellular trafficking and interactions of cytoplasmic HIV-1 Rev mutants in living cells. , 1998, Virology.