The binding of labelled tetrodotoxin to non‐myelinated nerve fibres

1. Tritiated tetrodotoxin has been prepared and purified, and its binding to rabbit, lobster, and garfish non‐myelinated nerve fibres examined.

[1]  E. Rideal Adsorption of Gases , 1932, Nature.

[2]  B. Takman,et al.  Potency Difference between the Zwitterion Form and the Cation Forms of Tetrodotoxin , 1967, Science.

[3]  R. Keynes,et al.  The movements of labelled ions in mammalian non‐myelinated nerve fibres. , 1965, The Journal of physiology.

[4]  D. Waud The rate of action of competitive neuromuscular blocking agents. , 1967, The Journal of pharmacology and experimental therapeutics.

[5]  C. Thron,et al.  The rate of action of atropine. , 1968, The Journal of pharmacology and experimental therapeutics.

[6]  H. Rang The kinetics of action of acetylcholine antagonists in smooth muscle , 1966, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[7]  J. M. Ritchie,et al.  The interaction at equilibrium between tetrodotoxin and mammalian non‐myelinated nerve fibres , 1972, The Journal of physiology.

[8]  A. Hill The mode of action of nicotine and curari, determined by the form of the contraction curve and the method of temperature coefficients , 1909, The Journal of physiology.

[9]  H. Mosher,et al.  TARICHATOXIN--TETRODOTOXIN: A POTENT NEUROTOXIN. , 1964, Science.

[10]  W. Paton,et al.  The margin of safety of neuromuscular transmission , 1967, The Journal of physiology.

[11]  L. M. Dorfman,et al.  Tritium Labelling of Organic Compounds by Means of Electric Discharge , 1959 .

[12]  H. Rang,et al.  The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors , 1965, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[13]  George A. Bray,et al.  A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter , 1960 .

[14]  D. M. Easton Impulses at the artifactual nerve end. , 1965, Cold Spring Harbor symposia on quantitative biology.

[15]  K. Sakai,et al.  ON THE STRUCTURE OF TETRODOTOXIN. , 1964, Chemical & pharmaceutical bulletin.

[16]  David Colquhoun,et al.  Lectures on biostatistics , 1972 .

[17]  B. Hille Pharmacological Modifications of the Sodium Channels of Frog Nerve , 1968, The Journal of general physiology.

[18]  W. Bowman Mode of Action of Drugs , 1964, Nature.

[19]  J. M. Ritchie,et al.  The ionic content of mammalian non‐myelinated nerve fibres and its alteration as a result of electrical activity , 1968, The Journal of physiology.

[20]  H. S. Gasser OLFACTORY NERVE FIBERS , 1956, The Journal of general physiology.

[21]  E. Albuquerque,et al.  Effects of batrachotoxin on nerve membrane potential and conductances. , 1971, Nature: New biology.

[22]  W. J. Adelman,et al.  Equilibrium and Kinetic Properties of the Interaction between Tetrodotoxin and the Excitable Membrane of the Squid Giant Axon , 1970, The Journal of general physiology.

[23]  W. Rushton A theory of the effects of fibre size in medullated nerve , 1951, The Journal of physiology.

[24]  K. Furusawa,et al.  The depolarization of crustacean nerve by stimulation or oxygen want , 1929, The Journal of physiology.

[25]  D. Hafemann Binding of radioactive tetrodotoxin to nerve membrane preparations. , 1972, Biochimica et biophysica acta.

[26]  J. Moore,et al.  An upper limit to the number of sodium channels in nerve membrane? , 1967, The Journal of physiology.

[27]  R. Keynes,et al.  The binding of tetrodotoxin to nerve membranes , 1971, The Journal of physiology.

[28]  D. Waud Pharmacological receptors. , 1968, Pharmacological reviews.

[29]  D. Colquhoun BALANCED INCOMPLETE BLOCK DESIGNS IN BIOLOGICAL ASSAY ILLUSTRATED BY THE ASSAY OF GASTRIN USING A YOUDEN SQUARE. , 1963, British journal of pharmacology and chemotherapy.

[30]  I. Langmuir THE ADSORPTION OF GASES ON PLANE SURFACES OF GLASS, MICA AND PLATINUM. , 1918 .

[31]  B. Hille,et al.  Ionic channels in nerve membranes. , 1970, Progress in biophysics and molecular biology.

[32]  P. Greengard,et al.  On the active structure of local anesthetics. , 1965, The Journal of pharmacology and experimental therapeutics.