Phosphorylation Status of Thymidine Kinase 1 Following Antiproliferative Drug Treatment Mediates 3′-Deoxy-3′-[18F]-Fluorothymidine Cellular Retention
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C. Patel | D. Mann | E. Aboagye | J. Steinke | R. Vilar | R. Sala | Q. Nguyen
[1] Eliot T. McKinley,et al. Limits of [18F]-FLT PET as a Biomarker of Proliferation in Oncology , 2013, PloS one.
[2] L. Carroll,et al. Synthesis and evaluation of nucleoside radiotracers for imaging proliferation. , 2012, Nuclear medicine and biology.
[3] J. Jacob,et al. Monitoring early response to taxane therapy in advanced breast cancer with circulating tumor cells and [(18)F] 3´-deoxy-3´-fluorothymidine PET: a pilot study. , 2012, Biomarkers in medicine.
[4] J. Christensen,et al. [18F]FLT–PET Imaging Does Not Always “Light Up” Proliferating Tumor Cells , 2011, Clinical Cancer Research.
[5] L. Rosso,et al. [18F]-3′Deoxy-3′-Fluorothymidine Positron Emission Tomography and Breast Cancer Response to Docetaxel , 2011, Clinical Cancer Research.
[6] H. Vesselle,et al. Tumor 3′-Deoxy-3′-18F-Fluorothymidine (18F-FLT) Uptake by PET Correlates with Thymidine Kinase 1 Expression: Static and Kinetic Analysis of 18F-FLT PET Studies in Lung Tumors , 2011, The Journal of Nuclear Medicine.
[7] Karl A. Merrick,et al. Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. , 2011, Molecular cell.
[8] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[9] S. Shousha,et al. Altered Tissue 3′-Deoxy-3′-[18F]Fluorothymidine Pharmacokinetics in Human Breast Cancer following Capecitabine Treatment Detected by Positron Emission Tomography , 2009, Clinical Cancer Research.
[10] S. Yao,et al. The Role of Human Nucleoside Transporters in Uptake of 3′-Deoxy-3′-fluorothymidine , 2008, Molecular Pharmacology.
[11] P. Workman,et al. Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901 , 2008, Molecular Cancer Therapeutics.
[12] S. Elledge,et al. A quantitative atlas of mitotic phosphorylation , 2008, Proceedings of the National Academy of Sciences.
[13] J. Bading,et al. Imaging of Cell Proliferation: Status and Prospects , 2008, Journal of Nuclear Medicine.
[14] P. Workman,et al. Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity , 2007, Molecular Cancer Therapeutics.
[15] Hubert Vesselle,et al. FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine. , 2007, Seminars in nuclear medicine.
[16] Pierre Dubus,et al. Cdk1 is sufficient to drive the mammalian cell cycle , 2007, Nature.
[17] Z. Chang,et al. Mitotic control of dTTP pool: a necessity or coincidence? , 2007, Journal of biomedical science.
[18] Steven P Gygi,et al. A probability-based approach for high-throughput protein phosphorylation analysis and site localization , 2006, Nature Biotechnology.
[19] Paul Workman,et al. In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography. , 2006, Cancer research.
[20] E. Kinoshita,et al. Phosphate-binding Tag, a New Tool to Visualize Phosphorylated Proteins*S , 2006, Molecular & Cellular Proteomics.
[21] A. Shields,et al. Positron Emission Tomography Measurement of Tumor Metabolism and Growth: Its Expanding Role in Oncology , 2006, Molecular Imaging and Biology.
[22] S. Shousha,et al. Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine-positron emission tomography imaging: evaluation of analytical methods. , 2005, Cancer research.
[23] P. Price,et al. The uptake of 3′-deoxy-3′-[18F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels , 2005, European Journal of Nuclear Medicine and Molecular Imaging.
[24] E. Kinoshita,et al. Novel immobilized zinc(II) affinity chromatography for phosphopeptides and phosphorylated proteins. , 2005, Journal of separation science.
[25] Mark Muzi,et al. Kinetic analysis of 3'-deoxy-3'-fluorothymidine PET studies: validation studies in patients with lung cancer. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[26] H. Eklund,et al. Structures of thymidine kinase 1 of human and mycoplasmic origin , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[27] A. Harris,et al. Measuring tumor pharmacodynamic response using PET proliferation probes: the case for 2-[(11)C]-thymidine. , 2004, Biochimica et biophysica acta.
[28] M. Muzi,et al. Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography. , 2004, Nuclear medicine and biology.
[29] Z. Chang,et al. Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site. , 2004, Biochemical and biophysical research communications.
[30] Z. Chang,et al. Mitotic Degradation of Human Thymidine Kinase 1 Is Dependent on the Anaphase-Promoting Complex/Cyclosome-Cdh1-Mediated Pathway , 2004, Molecular and Cellular Biology.
[31] P. Reichard,et al. Origins of mitochondrial thymidine triphosphate: Dynamic relations to cytosolic pools , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[32] A. Shields,et al. PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[33] Qimin He,et al. 3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. , 2003, Cancer research.
[34] Z. Chang,et al. Degradation of human thymidine kinase is dependent on serine-13 phosphorylation: involvement of the SCF-mediated pathway. , 2003, The Biochemical journal.
[35] Mark Muzi,et al. In vivo validation of 3'deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[36] H. Dittmann,et al. Early changes in [18F]FLT uptake after chemotherapy: an experimental study , 2002, European Journal of Nuclear Medicine and Molecular Imaging.
[37] L. Wiens,et al. Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[38] G. Glatting,et al. Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) in pancreatic cancer cell lines , 2002, European Journal of Nuclear Medicine and Molecular Imaging.
[39] Y. Yonekura,et al. Basis of FLT as a cell proliferation marker: comparative uptake studies with [3H]thymidine and [3H]arabinothymidine, and cell-analysis in 22 asynchronously growing tumor cell lines. , 2002, Nuclear medicine and biology.
[40] Otto Muzik,et al. Imaging proliferation in vivo with [F-18]FLT and positron emission tomography , 1998, Nature Medicine.
[41] Duen-Yi Huang,et al. Serine 13 Is the Site of Mitotic Phosphorylation of Human Thymidine Kinase* , 1998, The Journal of Biological Chemistry.
[42] G. Pfeifer,et al. Constitutive Protection of E2F Recognition Sequences in the Human Thymidine Kinase Promoter during Cell Cycle Progression* , 1997, The Journal of Biological Chemistry.
[43] Z. Chang,et al. Differential phosphorylation of human thymidine kinase in proliferating and M phase-arrested human cells. , 1994, The Journal of biological chemistry.
[44] W. Plunkett,et al. Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells. , 1993, The Journal of biological chemistry.
[45] B. Munch‐Petersen,et al. Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties. , 1993, The Journal of biological chemistry.
[46] Duen-Yi Huang,et al. The regulation of thymidine kinase in HL-60 human promyeloleukemia cells. , 1993, The Journal of biological chemistry.
[47] S. Eriksson,et al. Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. , 1991, The Journal of biological chemistry.
[48] T. Kelly,et al. Cell cycle regulation of thymidine kinase: residues near the carboxyl terminus are essential for the specific degradation of the enzyme at mitosis , 1991, Molecular and cellular biology.
[49] J. Sherley,et al. Regulation of human thymidine kinase during the cell cycle. , 1988, The Journal of biological chemistry.
[50] I. Scheffler,et al. Cell cycle-dependent regulation of thymidine kinase activity introduced into mouse LMTK- cells by DNA and chromatin-mediated gene transfer. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[51] J. Steinkamp,et al. RAPID, SIMULTANEOUS MEASUREMENT OF DNA, PROTEIN, AND CELL VOLUME IN SINGLE CELLS FROM LARGE MAMMALIAN CELL POPULATIONS , 1973, The Journal of cell biology.
[52] E. Kinoshita,et al. Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE , 2009, Nature Protocols.
[53] D O Morgan,et al. Cyclin-dependent kinases: engines, clocks, and microprocessors. , 1997, Annual review of cell and developmental biology.
[54] Elias S. J. Arnér,et al. Mammalian deoxyribonucleoside kinases. , 1995, Pharmacology & therapeutics.