A comparison of three imaging algorithms on reconstructing tumor target in acoustic heterogeneous tissue with realistic numerical breast phantoms in microwave induced thermo-acoustic tomography

Accurately reconstruct the tumor target in an acoustic heterogeneous tissue is a hot research issue in thermo-acoustic tomography (TAT). In this paper, we present three imaging algorithms for microwave induced thermo-acoustic tomography (MITAT): time reversal mirror (TRM), active adjoint modeling (AAM) method and iterative reconstruction method (IRM). The performance of the three imaging methods for reconstructing tumor target in heterogeneous breast tissue are verified and compared by using the anatomically realistic numerical breast phantoms derived from T1-weighted MRIs of prone patients. Through the simulation results, the IRM proves to have better imaging results than TRM and consume much less computing time than AAM. The IRM is a promising approach for imaging tumor target in heterogeneous breast tissue in TAT.

[1]  J. D. Shea,et al.  Contrast-enhanced microwave imaging of breast tumors: a computational study using 3D realistic numerical phantoms , 2010, Inverse problems.

[2]  Guust Nolet,et al.  Three-dimensional sensitivity kernels for finite-frequency traveltimes: the banana–doughnut paradox , 1999 .

[3]  Plamen Stefanov,et al.  Thermoacoustic tomography arising in brain imaging , 2010, 1009.1687.

[4]  Qing Huo Liu,et al.  RECONSTRUCTION OF MICROWAVE ABSORPTION PROPERTIES IN HETEROGENEOUS TISSUE FOR MICROWAVE-INDUCED THERMO-ACOUSTIC TOMOGRAPHY , 2012 .

[5]  Mohammed Ghanbari,et al.  Scope of validity of PSNR in image/video quality assessment , 2008 .

[6]  Barry D. Van Veen,et al.  Development of Anatomically Realistic Numerical Breast Phantoms With Accurate Dielectric Properties for Modeling Microwave Interactions With the Human Breast , 2008, IEEE Transactions on Biomedical Engineering.

[7]  Mark A. Anastasio,et al.  3D laser optoacoustic ultrasonic imaging system for research in mice (LOUIS-3DM) , 2014, Photonics West - Biomedical Optics.

[8]  Lihong V. Wang,et al.  Thermoacoustic tomography with correction for acoustic speed variations , 2006, Physics in medicine and biology.

[9]  Guust Nolet,et al.  Fréchet kernels for finite-frequency traveltimes—I. Theory , 2000 .

[10]  D. Xing,et al.  The feasibility of using microwave-induced thermoacoustic tomography for detection and evaluation of renal calculi , 2010, Physics in Medicine and Biology.

[11]  Hao Xin,et al.  Microwave-Induced Thermoacoustic Imaging Model for Potential Breast Cancer Detection , 2012, IEEE Transactions on Biomedical Engineering.

[12]  D. Xing,et al.  Ultrashort microwave-induced thermoacoustic imaging: a breakthrough in excitation efficiency and spatial resolution. , 2012, Physical review letters.

[13]  Lorenzo Crocco,et al.  An Effective Procedure for MNP-Enhanced Breast Cancer Microwave Imaging , 2014, IEEE Transactions on Biomedical Engineering.

[14]  Yulia Hristova,et al.  Time reversal in thermoacoustic tomography—an error estimate , 2008, 0812.0606.

[15]  Yuan Xu,et al.  Transcranial Thermoacoustic Tomography: A Comparison of Two Imaging Algorithms , 2013, IEEE Transactions on Medical Imaging.

[16]  Yuan Xu,et al.  Effects of acoustic heterogeneity in breast thermoacoustic tomography , 2003, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[17]  Qing Huo Liu,et al.  Microwave-Induced Thermal Acoustic Tomography for Breast Tumor Based on Compressive Sensing , 2013, IEEE Transactions on Biomedical Engineering.

[18]  Wiendelt Steenbergen,et al.  Speed-of-sound compensated photoacoustic tomography for accurate imaging. , 2012, Medical physics.

[19]  Zaiping Nie,et al.  System Development of Microwave Induced Thermo-Acoustic Tomography and Experiments on Breast Tumor , 2013 .

[20]  Klaus Mueller,et al.  Refraction corrected transmission ultrasound computed tomography for application in breast imaging. , 2010, Medical physics.

[21]  Linh V. Nguyen,et al.  Reconstruction and time reversal in thermoacoustic tomography in acoustically homogeneous and inhomogeneous media , 2008 .

[22]  S. Hagness,et al.  Toward contrast-enhanced microwave-induced thermoacoustic imaging of breast cancer: an experimental study of the effects of microbubbles on simple thermoacoustic targets , 2009, Physics in medicine and biology.

[23]  Qinya Liu,et al.  Tomography, Adjoint Methods, Time-Reversal, and Banana-Doughnut Kernels , 2004 .

[24]  Jian Li,et al.  Adaptive and Robust Methods of Reconstruction (ARMOR) for Thermoacoustic Tomography , 2008, IEEE Transactions on Biomedical Engineering.

[25]  Bradley E. Treeby,et al.  Artifact Trapping During Time Reversal Photoacoustic Imaging for Acoustically Heterogeneous Media , 2010, IEEE Transactions on Medical Imaging.

[26]  Da Xing,et al.  Microwave-induced thermoacoustic computed tomography with a clinical contrast agent of NMG2[Gd(DTPA)] , 2012 .

[27]  Qing Huo Liu,et al.  Active Adjoint Modeling Method in Microwave Induced Thermoacoustic Tomography for Breast Tumor , 2014, IEEE Transactions on Biomedical Engineering.

[28]  Lihong V. Wang,et al.  Enhancement of photoacoustic tomography by ultrasonic computed tomography based on optical excitation of elements of a full-ring transducer array. , 2013, Optics letters.

[29]  A. Kak,et al.  Simultaneous Algebraic Reconstruction Technique (SART): A Superior Implementation of the Art Algorithm , 1984, Ultrasonic imaging.

[30]  S. Sanei Characterisation of fat and malignancy in transmissive ultrasound breast tomographs applying fuzzy logic , 1998, Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286).

[31]  D. Xing,et al.  Three-dimensional thermoacoustic imaging for early breast cancer detection. , 2012, Medical physics.

[32]  Gerard T. Schuster,et al.  Wave-equation traveltime inversion , 1991 .

[33]  Andreas Fichtner,et al.  The adjoint method in seismology – I. Theory , 2006 .

[34]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries , 2007, Physics in medicine and biology.

[35]  Da Xing,et al.  Thermoacoustic molecular tomography with magnetic nanoparticle contrast agents for targeted tumor detection. , 2010, Medical physics.

[36]  Qing Huo Liu The pseudospectral time-domain (PSTD) algorithm for acoustic waves in absorptive media , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[37]  Z. Nie,et al.  Computational Study of Time Reversal Mirror Technique for Microwave-Induced Thermo-Acoustic Tomography , 2008 .

[38]  Qing Huo Liu,et al.  AN INTEGRATED SIMULATION APPROACH AND EXPERIMENTAL RESEARCH ON MICROWAVE INDUCED THERMO-ACOUSTIC TOMOGRAPHY SYSTEM , 2013 .