Comparative evaluation of lignocaine and lignocainebupivacaine for lumbo-sacral epidural block in diazepam sedated West African dwarf goats

This study compared the onset of neural blockade, onset and duration of analgesia and duration of recumbency produced in five healthy West African Dwarf (WAD) goats by the lumbo-sacral epidural injections of a mixture of 2mg/kg lignocaine 2% solution and 0.95mg/kg bupivacaine 0.5% solution (LBM) and 4mg/kg lignocaine 2% solution. Associated changes in heart rate (HR), respiratory rate (RR) and rectal temperature (RT) were recorded at 10-min intervals in the initial 1 hour. The onset of neural blockade with LBM (9.6±2.7 min) was significantly (p 0.05) in the physiological parameters between the two groups. It was concluded that epidurally administered LBM had a slower onset of neural blockade but longer onset of analgesia, duration of analgesia and duration of recumbency than with LIG in diazepam-sedated goats. The epidural blockade also produced insignificant changes in the mean HR, RR, and RT responses of the experiment to both drug protocols. Keywords : Bupivacaine, Epidural, Goats, Lignocaine; Loco-regional, Sedation

[1]  A. Adetunji,et al.  Evaluation of lignocaine/bupivacaine mixture for central neural blockade in goats. , 2009 .

[2]  Ruben A. Lee,et al.  Factors Affecting the Distribution of Neural Blockade by Local Anesthetics in Epidural Anesthesia and a Comparison of Lumbar Versus Thoracic Epidural Anesthesia , 2008, Anesthesia and analgesia.

[3]  O. Hodgkinson,et al.  Practical anaesthesia and analgesia in sheep, goats and calves , 2007, In Practice.

[4]  E. Hofmeister,et al.  Effect of body position on cranial migration of epidurally injected methylene blue in recumbent dogs. , 2006, American journal of veterinary research.

[5]  S. Fubini,et al.  Farm animal surgery. , 2004 .

[6]  O. Idowu,et al.  Distribution of surgical cases at the university of Nigeria veterinary teaching hospital (1985 — 1995) , 2002 .

[7]  S. Luna,et al.  Epidural anaesthesia using lignocaine, bupivacaine or a mixture of lignocaine and bupivacaine in dogs , 1997 .

[8]  P. Taylor.  Anaesthesia in sheep and goats , 1991, In Practice.

[9]  C. Trim.  Epidural analgesia with 0.75% bupivacaine for laparotomy in goats. , 1989, Journal of the American Veterinary Medical Association.

[10]  B. Finucane,et al.  Influence of Age on Vascular Absorption of Lidocaine from the Epidural Space , 1987, Anesthesia and analgesia.

[11]  B. Covino,et al.  Pharmacology of local anaesthetic agents. , 1986, British journal of anaesthesia.

[12]  L. Mather,et al.  Lidocaine and Bupivacaine Mixtures for Epidural Blockade , 1982, Anesthesiology.

[13]  R. Hodgkinson,et al.  Obesity, gravity, and spread of epidural anesthesia. , 1981 .

[14]  S. I. Kim,et al.  Age and the Spread of Local Anesthetic Solutions in the Epidural Space , 1980, Anesthesia and analgesia.

[15]  C. Devendra.  Potential of Sheep and Goats in Less Developed Countries , 1980 .

[16]  J. Thurmon,et al.  Spinal analgesia and sedation of goats with lignocaine and xylazine , 1979, Veterinary Record.

[17]  J. Shilkin.  Diseases of goats , 1960 .