In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry

[1]  Ying Ge,et al.  Top-down targeted proteomics for deep sequencing of tropomyosin isoforms. , 2013, Journal of proteome research.

[2]  Ying Ge,et al.  Purification and high-resolution top-down mass spectrometric characterization of human salivary α-amylase. , 2012, Analytical chemistry.

[3]  Ying Ge,et al.  Comprehensive Analysis of Protein Modifications by Top-Down Mass Spectrometry , 2011, Circulation. Cardiovascular genetics.

[4]  Ying Ge,et al.  Augmented Phosphorylation of Cardiac Troponin I in Hypertensive Heart Failure* , 2011, The Journal of Biological Chemistry.

[5]  Ying Ge,et al.  Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. , 2011, Journal of proteome research.

[6]  Qingge Xu,et al.  Top-down high-resolution electron capture dissociation mass spectrometry for comprehensive characterization of post-translational modifications in Rhesus monkey cardiac troponin I , 2011 .

[7]  Qingge Xu,et al.  Phosphorylation, but not alternative splicing or proteolytic degradation, is conserved in human and mouse cardiac troponin T. , 2011, Biochemistry.

[8]  G. Boivin,et al.  Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity , 2010, Journal of Muscle Research and Cell Motility.

[9]  G. Jagatheesan,et al.  Investigations into tropomyosin function using mouse models. , 2010, Journal of molecular and cellular cardiology.

[10]  J. Bowie,et al.  Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation* , 2010, Molecular & Cellular Proteomics.

[11]  G. Boivin,et al.  Molecular and Functional Characterization of a Novel Cardiac-Specific Human Tropomyosin Isoform , 2009, Circulation.

[12]  Ying Ge,et al.  In vivo phosphorylation site mapping in mouse cardiac troponin I by high resolution top-down electron capture dissociation mass spectrometry: Ser22/23 are the only sites basally phosphorylated. , 2009, Biochemistry.

[13]  Ying Ge,et al.  Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state , 2009, Proceedings of the National Academy of Sciences.

[14]  Ying Ge,et al.  Single amino acid sequence polymorphisms in rat cardiac troponin revealed by top–down tandem mass spectrometry , 2009, Journal of Muscle Research and Cell Motility.

[15]  V. Zabrouskov,et al.  Unraveling Molecular Complexity of Phosphorylated Human Cardiac Troponin I by Top Down Electron Capture Dissociation/Electron Transfer Dissociation Mass Spectrometry*S , 2008, Molecular & Cellular Proteomics.

[16]  P. Gunning Introduction and historical perspective. , 2008, Advances in experimental medicine and biology.

[17]  R. Solaro,et al.  Use of 2‐D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy , 2008, Proteomics.

[18]  G. Jagatheesan,et al.  The role of tropomyosin in heart disease. , 2008, Advances in experimental medicine and biology.

[19]  J. Huot,et al.  DAP kinase mediates the phosphorylation of tropomyosin-1 downstream of the ERK pathway, which regulates the formation of stress fibers in response to oxidative stress , 2007, Journal of Cell Science.

[20]  N. Kelleher,et al.  Decoding protein modifications using top-down mass spectrometry , 2007, Nature Methods.

[21]  P. D. de Tombe,et al.  p38-MAPK Induced Dephosphorylation of &agr;-Tropomyosin Is Associated With Depression of Myocardial Sarcomeric Tension and ATPase Activity , 2007, Circulation research.

[22]  Neil L Kelleher,et al.  Precise and Parallel Characterization of Coding Polymorphisms, Alternative Splicing, and Modifications in Human Proteins by Mass Spectrometry*S , 2005, Molecular & Cellular Proteomics.

[23]  D. Dube,et al.  Expression of a novel cardiac-specific tropomyosin isoform in humans. , 2004, Biochemical and biophysical research communications.

[24]  S. Perry Vertebrate tropomyosin: distribution, properties and function , 2004, Journal of Muscle Research & Cell Motility.

[25]  Steven B Marston,et al.  Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications. , 2003, Circulation research.

[26]  J. V. Van Eyk,et al.  Application of reversed phase high performance liquid chromatography for subproteomic analysis of cardiac muscle , 2002, Proteomics.

[27]  F. McLafferty,et al.  Electron capture dissociation for structural characterization of multiply charged protein cations. , 2000, Analytical chemistry.

[28]  G. Boivin,et al.  β-Tropomyosin Overexpression Induces Severe Cardiac Abnormalities , 1998 .

[29]  G. Boivin,et al.  Beta-tropomyosin overexpression induces severe cardiac abnormalities. , 1998, Journal of molecular and cellular cardiology.

[30]  R. Solaro,et al.  Exchange of - for -Tropomyosin in Hearts of Transgenic Mice Induces Changes in Thin Filament Response to Ca, Strong Cross-bridge Binding, and Protein Phosphorylation (*) , 1996, The Journal of Biological Chemistry.

[31]  G. Boivin,et al.  Molecular and Physiological Effects of Overexpressing Striated Muscle β-Tropomyosin in the Adult Murine Heart (*) , 1995, The Journal of Biological Chemistry.

[32]  F W McLafferty,et al.  Collisional activation of large multiply charged ions using Fourier transform mass spectrometry. , 1994, Analytical chemistry.

[33]  D. Wieczorek Regulation of alternatively spliced alpha-tropomyosin gene expression by nerve extract. , 1988, The Journal of biological chemistry.

[34]  C. W. Smith,et al.  The rat alpha-tropomyosin gene generates a minimum of six different mRNAs coding for striated, smooth, and nonmuscle isoforms by alternative splicing , 1988, Molecular and cellular biology.

[35]  M. Bárány,et al.  Specific phosphorylation at serine-283 of alpha tropomyosin from frog skeletal and rabbit skeletal and cardiac muscle. , 1978, Proceedings of the National Academy of Sciences of the United States of America.