Solid freeform fabrication technology applied to tissue engineering with various biomaterials

An important component in tissue engineering is the three-dimensional (3D) scaffold, which guides cells to form target tissue, maintains tissue volume, and provides sufficient structural support during tissue regeneration. However, until recently, conventional scaffold fabrication methods have not satisfied the requirements for tissue regeneration. The development of additive fabrication technologies, known as solid freeform fabrication (SFF), has made it possible to fabricate scaffolds with very fine structures and complex geometries using computer-aided design (CAD) data acquired from medical images of patients. Due to the advantages of SFF technology, it is rapidly becoming the technique of choice for scaffold fabrication. Moreover, recent research has demonstrated that a variety of biomaterials are suitable for use in various SFF systems. This paper reviews the application, advancement, and potential of SFF technologies in the fabrication of scaffolds for tissue regeneration.

[1]  Il Keun Kwon,et al.  Photo-polymerized microarchitectural constructs prepared by microstereolithography (muSL) using liquid acrylate-end-capped trimethylene carbonate-based prepolymers. , 2005, Biomaterials.

[2]  Dong-Woo Cho,et al.  Fabrication and characteristic analysis of a poly(propylene fumarate) scaffold using micro-stereolithography technology. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.

[3]  Colleen L Flanagan,et al.  Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. , 2005, Biomaterials.

[4]  Joel W. Barlow,et al.  Materials for biomedical applications , 1999 .

[5]  Margam Chandrasekaran,et al.  Rapid prototyping in tissue engineering: challenges and potential. , 2004, Trends in biotechnology.

[6]  K. Leong,et al.  Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. , 2003, Biomaterials.

[7]  Wei Sun,et al.  Multi‐nozzle deposition for construction of 3D biopolymer tissue scaffolds , 2005 .

[8]  Dong-Woo Cho,et al.  Application of microstereolithography in the development of three-dimensional cartilage regeneration scaffolds , 2008, Biomedical microdevices.

[9]  Geoffrey R. Mitchell,et al.  Stereo‐thermal‐lithography: a new principle for rapid prototyping , 2003 .

[10]  G. Vunjak‐Novakovic,et al.  Culture of organized cell communities. , 1998, Advanced drug delivery reviews.

[11]  Dong-Woo Cho,et al.  Solid Free‐Form Fabrication of Tissue‐Engineering Scaffolds with a Poly(lactic‐co‐glycolic acid) Grafted Hyaluronic Acid Conjugate Encapsulating an Intact Bone Morphogenetic Protein–2/Poly(ethylene glycol) Complex , 2011 .

[12]  F. E. Wiria,et al.  Poly-ε-caprolactone/hydroxyapatite for tissue engineering scaffold fabrication via selective laser sintering , 2007 .

[13]  Wei Sun,et al.  Fabrication of three-dimensional polycaprolactone/hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro. , 2007, Biomaterials.

[14]  D. Cho,et al.  Bone regeneration using a microstereolithography-produced customized poly(propylene fumarate)/diethyl fumarate photopolymer 3D scaffold incorporating BMP-2 loaded PLGA microspheres. , 2011, Biomaterials.

[15]  S. Badylak,et al.  Oxygen diffusivity of biologic and synthetic scaffold materials for tissue engineering. , 2009, Journal of biomedical materials research. Part A.

[16]  K. Kataoka,et al.  Immobilization of laminin peptide in molecularly aligned chitosan by covalent bonding. , 2005, Biomaterials.

[17]  Dong-Woo Cho,et al.  Development of a bi-pore scaffold using indirect solid freeform fabrication based on microstereolithography technology , 2009 .

[18]  C. V. van Blitterswijk,et al.  Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique. , 2004, Biomaterials.

[19]  K. Leong,et al.  The design of scaffolds for use in tissue engineering. Part I. Traditional factors. , 2001, Tissue engineering.

[20]  Stephen J. Haines,et al.  Repairing Holes in the Head: A History of Cranioplasty , 1997 .

[21]  R Langer,et al.  Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents. , 1996, Biomaterials.

[22]  J. Gatica,et al.  Oxygen diffusion through natural extracellular matrices: implications for estimating "critical thickness" values in tendon tissue engineering. , 2008, Tissue engineering. Part A.

[23]  Vladimir Mironov,et al.  Organ printing: computer-aided jet-based 3D tissue engineering. , 2003, Trends in biotechnology.

[24]  David Sedmera,et al.  The oldest, toughest cells in the heart. , 2003, Novartis Foundation symposium.

[25]  Dong-Woo Cho,et al.  Development of an indirect solid freeform fabrication process based on microstereolithography for 3D porous scaffolds , 2008 .

[26]  P. Calvert.  Printing Cells , 2007, Science.

[27]  Mattie S. M. Timmer,et al.  Fabrication of three-dimensional scaffolds using precision extrusion deposition with an assisted cooling device , 2011, Biofabrication.

[28]  L. Niklason,et al.  Scaffold-free vascular tissue engineering using bioprinting. , 2009, Biomaterials.

[29]  Jaesung Park,et al.  Development of a hybrid scaffold with synthetic biomaterials and hydrogel using solid freeform fabrication technology , 2011, Biofabrication.

[30]  Vladimir Mironov,et al.  Organ printing: tissue spheroids as building blocks. , 2009, Biomaterials.

[31]  E. Sachlos,et al.  Making tissue engineering scaffolds work. Review: the application of solid freeform fabrication technology to the production of tissue engineering scaffolds. , 2003, European cells & materials.

[32]  Dietmar W. Hutmacher,et al.  Scaffold design and fabrication technologies for engineering tissues — state of the art and future perspectives , 2001, Journal of biomaterials science. Polymer edition.

[33]  T. Boland,et al.  Inkjet printing of viable mammalian cells. , 2005, Biomaterials.

[34]  Dong-Woo Cho,et al.  Development of 3D PPF/DEF scaffolds using micro-stereolithography and surface modification , 2009, Journal of materials science. Materials in medicine.

[35]  I Zein,et al.  Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. , 2001, Journal of biomedical materials research.

[36]  Toshiki Niino,et al.  Avidin-biotin binding-based cell seeding and perfusion culture of liver-derived cells in a porous scaffold with a three-dimensional interconnected flow-channel network. , 2007, Biomaterials.

[37]  Nuno Carpinteiro André,et al.  Virtual and Rapid Manufacturing: Advanced Research in Virtual and Rapid Prototyping , 2007 .

[38]  K. Leong,et al.  Scaffold development using selective laser sintering of polyetheretherketone-hydroxyapatite biocomposite blends. , 2003, Biomaterials.

[39]  Dietmar W Hutmacher,et al.  Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. , 2004, Trends in biotechnology.

[40]  Malcolm N. Cooke,et al.  Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth. , 2003, Journal of biomedical materials research. Part B, Applied biomaterials.

[41]  Dong-Woo Cho,et al.  Fabrication of a SFF-based three-dimensional scaffold using a precision deposition system in tissue engineering , 2008 .

[42]  Patrice L. Baldeck,et al.  Two-photon absorption: from optical power limiting to 3D microfabrication , 2005 .

[43]  James J. Yoo,et al.  The realistic prediction of oxygen transport in a tissue-engineered scaffold by introducing time-varying effective diffusion coefficients. , 2011, Acta biomaterialia.

[44]  K. Leong,et al.  Fabrication of controlled release biodegradable foams by phase separation. , 1995, Tissue engineering.

[45]  D. Cho,et al.  Evaluation of solid free-form fabrication-based scaffolds seeded with osteoblasts and human umbilical vein endothelial cells for use in vivo osteogenesis. , 2010, Tissue engineering. Part A.

[46]  R. Liska,et al.  Photopolymers for Rapid Prototyping of Soluble Mold Materials and Molding of Cellular Biomaterials , 2006 .

[47]  S. Hollister.  Porous scaffold design for tissue engineering , 2005, Nature materials.

[48]  Minna Kellomäki,et al.  A review of rapid prototyping techniques for tissue engineering purposes , 2008, Annals of medicine.

[49]  Tao Xu,et al.  Advances in tissue engineering: cell printing. , 2005, The Journal of thoracic and cardiovascular surgery.

[50]  Ivan Martin,et al.  In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bone‐like tissues , 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[51]  J. Vacanti,et al.  Tissue engineering : Frontiers in biotechnology , 1993 .

[52]  Wei Sun,et al.  Recent development on computer aided tissue engineering - a review , 2002, Comput. Methods Programs Biomed..

[53]  Satoshi Kawata,et al.  Two-photon photopolymerization as a tool for making micro-devices , 2003 .