Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

[1]  S. Ghaffari,et al.  Transcription factors FOXO in the regulation of homeostatic hematopoiesis , 2018, Current opinion in hematology.

[2]  Yi-xuan Yang,et al.  Inhibition of CD9 expression reduces the metastatic capacity of human hepatocellular carcinoma cell line MHCC97-H. , 2018, International journal of oncology.

[3]  S. Levy,et al.  Immune Targeting of Tetraspanins Involved in Cell Invasion and Metastasis , 2018, Front. Immunol..

[4]  Alissa M. Weaver,et al.  Extracellular vesicles: important collaborators in cancer progression. , 2018, Essays in biochemistry.

[5]  Noritada Kaji,et al.  Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells , 2018, Scientific Reports.

[6]  D. Guidolin,et al.  G protein-coupled receptor-receptor interactions give integrative dynamics to intercellular communication , 2018, Reviews in the neurosciences.

[7]  M. Zöller.  Janus-Faced Myeloid-Derived Suppressor Cell Exosomes for the Good and the Bad in Cancer and Autoimmune Disease , 2018, Front. Immunol..

[8]  M. Zöller,et al.  Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51. , 2018, Biochimica et biophysica acta. Molecular cell research.

[9]  M. Zöller,et al.  Corrigendum to "Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51" [Biochim. Biophys. Acta 1865(2) (2018) 379-391]. , 2018, Biochimica et biophysica acta. Molecular cell research.

[10]  J. Neefjes,et al.  Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling , 2018, The Journal of cell biology.

[11]  S. Turunen,et al.  Membrane-type matrix metalloproteases as diverse effectors of cancer progression. , 2017, Biochimica et biophysica acta. Molecular cell research.

[12]  Hua-Chuan Zheng.  The molecular mechanisms of chemoresistance in cancers , 2017, Oncotarget.

[13]  R. Cerione,et al.  Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake. , 2017, Seminars in cell & developmental biology.

[14]  S. Ghaffari,et al.  Mitochondria and FOXO3 in stem cell homeostasis, a window into hematopoietic stem cell fate determination , 2017, Journal of Bioenergetics and Biomembranes.

[15]  C. Weston,et al.  CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma , 2017, American journal of physiology. Gastrointestinal and liver physiology.

[16]  M. Zöller,et al.  Joint features and complementarities of Tspan8 and CD151 revealed in knockdown and knockout models. , 2017, Biochemical Society transactions.

[17]  T. Whiteside,et al.  The emerging roles of tumor-derived exosomes in hematological malignancies , 2017, Leukemia.

[18]  Marcel Mettlen,et al.  Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis. , 2017, Developmental cell.

[19]  Guoqiang Chen,et al.  Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. , 2016, The Journal of clinical investigation.

[20]  Yuan-yi Wei,et al.  Pathway-related molecules of VEGFC/D-VEGFR3/NRP2 axis in tumor lymphangiogenesis and lymphatic metastasis. , 2016, Clinica chimica acta; international journal of clinical chemistry.

[21]  W. Lee,et al.  Therapeutic targeting of tetraspanin8 in epithelial ovarian cancer invasion and metastasis , 2016, Oncogene.

[22]  J. Dudka,et al.  An outline of main factors of drug resistance influencing cancer therapy , 2016, Journal of chemotherapy.

[23]  E. Odintsova,et al.  ErbB receptors and tetraspanins: Casting the net wider. , 2016, The international journal of biochemistry & cell biology.

[24]  P. Fisher,et al.  Tetraspanin 8 mediates AEG‐1‐induced invasion and metastasis in hepatocellular carcinoma cells , 2016, FEBS letters.

[25]  M. Zöller,et al.  CD44v6-competent tumor exosomes promote motility, invasion and cancer-initiating cell marker expression in pancreatic and colorectal cancer cells , 2016, Oncotarget.

[26]  Weiwei Qi,et al.  Tspan9 inhibits the proliferation, migration and invasion of human gastric cancer SGC7901 cells via the ERK1/2 pathway. , 2016, Oncology reports.

[27]  Yan Zhao,et al.  Tetraspanin-8 promotes hepatocellular carcinoma metastasis by increasing ADAM12m expression , 2016, Oncotarget.

[28]  Jenna L. Dziki,et al.  Matrix-bound nanovesicles within ECM bioscaffolds , 2016, Science Advances.

[29]  S. Iwata,et al.  Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains. , 2016, Biochemical and biophysical research communications.

[30]  Hong-Jian Zhu,et al.  Extracellular vesicle isolation and characterization: toward clinical application. , 2016, The Journal of clinical investigation.

[31]  Raghu Kalluri,et al.  The biology and function of exosomes in cancer. , 2016, The Journal of clinical investigation.

[32]  C. Théry,et al.  Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes , 2016, Proceedings of the National Academy of Sciences.

[33]  I. Bednarek,et al.  The role of NANOG transcriptional factor in the development of malignant phenotype of cancer cells , 2016, Cancer biology & therapy.

[34]  M. Amiji,et al.  Exosome mediated communication within the tumor microenvironment. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[35]  P. Carmeliet,et al.  The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis , 2015, Science Signaling.

[36]  K. Vanderkerken,et al.  The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells , 2015, Oncotarget.

[37]  C. Antonescu,et al.  Charming neighborhoods on the cell surface: plasma membrane microdomains regulate receptor tyrosine kinase signaling. , 2015, Cellular signalling.

[38]  R. Segal,et al.  CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion , 2015, Oncotarget.

[39]  F. André,et al.  Targeting FGFR Signaling in Cancer , 2015, Clinical Cancer Research.

[40]  M. Zöller,et al.  The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities , 2015, Cell Communication and Signaling.

[41]  C. Bogani,et al.  Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis , 2015, Haematologica.

[42]  Fei Li,et al.  Integrin α6β1 Expressed in ESCs Instructs the Differentiation to Endothelial Cells , 2015, Stem cells.

[43]  J. Joseph,et al.  The CXCR4/CXCR7/CXCL12 Axis Is Involved in a Secondary but Complex Control of Neuroblastoma Metastatic Cell Homing , 2015, PloS one.

[44]  Xuetao Cao,et al.  The exosomes in tumor immunity , 2015, Oncoimmunology.

[45]  G. Weber,et al.  Interactions between osteopontin and vascular endothelial growth factor: Implications for cancer. , 2015, Biochimica et biophysica acta.

[46]  Hong-Jian Zhu,et al.  Emerging roles of exosomes during epithelial-mesenchymal transition and cancer progression. , 2015, Seminars in cell & developmental biology.

[47]  W. Liu,et al.  Over-expression of tetraspanin 8 in malignant glioma regulates tumor cell progression. , 2015, Biochemical and biophysical research communications.

[48]  Sijian Pan,et al.  Tetraspanin 8-Rictor-Integrin α3 Complex Is Required for Glioma Cell Migration , 2015, International journal of molecular sciences.

[49]  Zheng-xiang Liu,et al.  Involvement of activation of C-met signaling pathway in CD151-induced HUVECs angiogenesis , 2015, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

[50]  M. Zöller,et al.  The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding , 2014, Oncotarget.

[51]  J. Medema,et al.  Cancer stem cells – important players in tumor therapy resistance , 2014, The FEBS journal.

[52]  C. Théry,et al.  Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. , 2014, Annual review of cell and developmental biology.

[53]  M. Zöller,et al.  Outsmart tumor exosomes to steal the cancer initiating cell its niche. , 2014, Seminars in cancer biology.

[54]  D. Medici,et al.  Signaling mechanisms of the epithelial-mesenchymal transition , 2014, Science Signaling.

[55]  M. Yáñez-Mó,et al.  Tetraspanins in Extracellular Vesicle Formation and Function , 2014, Front. Immunol..

[56]  Clotilde Théry,et al.  Biogenesis and secretion of exosomes. , 2014, Current opinion in cell biology.

[57]  R. Weinberg,et al.  The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis , 2014, Nature Cell Biology.

[58]  R. Adams,et al.  Regulation of signaling interactions and receptor endocytosis in growing blood vessels , 2014, Cell adhesion & migration.

[59]  M. Parsons,et al.  Integrin α3β1–CD151 complex regulates dimerization of ErbB2 via RhoA , 2014, Oncogene.

[60]  N. Kosaka,et al.  Dark side of the exosome: the role of the exosome in cancer metastasis and targeting the exosome as a strategy for cancer therapy. , 2014, Future oncology.

[61]  M. Egger,et al.  Effects of erythropoiesis-stimulating agents on fatigue- and anaemia-related symptoms in cancer patients: systematic review and meta-analyses of published and unpublished data , 2014, British Journal of Cancer.

[62]  P. Zhao,et al.  How hepatitis C virus invades hepatocytes: the mystery of viral entry. , 2014, World journal of gastroenterology.

[63]  A. Ranjan,et al.  Glycosylation of the laminin receptor (α3β1) regulates its association with tetraspanin CD151: Impact on cell spreading, motility, degradation and invasion of basement membrane by tumor cells. , 2014, Experimental cell research.

[64]  R. V. van Etten,et al.  Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche. , 2014, Blood.

[65]  Samy Lamouille,et al.  Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.

[66]  P. Insel,et al.  Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling. , 2014, Biochimica et biophysica acta.

[67]  B. Teicher.  Targets in small cell lung cancer. , 2014, Biochemical pharmacology.

[68]  M. Hemler.  Tetraspanin proteins promote multiple cancer stages , 2013, Nature Reviews Cancer.

[69]  Paola Chiarugi,et al.  Anoikis molecular pathways and its role in cancer progression. , 2013, Biochimica et biophysica acta.

[70]  R. Meshram,et al.  Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth. , 2013, Progress in biophysics and molecular biology.

[71]  Blake R. C. Smith,et al.  Tetraspanin CD9 Promotes the Invasive Phenotype of Human Fibrosarcoma Cells via Upregulation of Matrix Metalloproteinase-9 , 2013, PloS one.

[72]  A. Sonnenberg,et al.  Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of Cd151 , 2013, The Journal of investigative dermatology.

[73]  T. Ludwig,et al.  The tetraspanin network modulates MT1-MMP cell surface trafficking. , 2013, The international journal of biochemistry & cell biology.

[74]  D. Anstee,et al.  Tetraspanins CD81 and CD82 Facilitate α4β1-Mediated Adhesion of Human Erythroblasts to Vascular Cell Adhesion Molecule-1 , 2013, PloS one.

[75]  S. Rose-John.  ADAM17, shedding, TACE as therapeutic targets. , 2013, Pharmacological research.

[76]  A. Möller,et al.  The pre-metastatic niche: finding common ground , 2013, Cancer and Metastasis Reviews.

[77]  A. Griffioen,et al.  Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-β1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo* , 2013, The Journal of Biological Chemistry.

[78]  R. Adams,et al.  Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor–specific angiogenic signaling , 2013, Molecular biology of the cell.

[79]  S. Rome,et al.  Endometrial Exosomes/Microvesicles in the Uterine Microenvironment: A New Paradigm for Embryo-Endometrial Cross Talk at Implantation , 2013, PloS one.

[80]  D. Mazurov,et al.  Tetraspanin protein CD9 interacts with metalloprotease CD10 and enhances its release via exosomes , 2013, The FEBS journal.

[81]  C. Figdor,et al.  ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9 , 2013, Cellular and Molecular Life Sciences.

[82]  Daowen Wang,et al.  The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence , 2012, Molecular medicine reports.

[83]  K. Maruyama,et al.  Deletion of Tetraspanin CD9 Diminishes Lymphangiogenesis in Vivo and in Vitro* , 2012, The Journal of Biological Chemistry.

[84]  J. Izbicki,et al.  Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer , 2012, PloS one.

[85]  M. Zöller,et al.  Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection. , 2012, The international journal of biochemistry & cell biology.

[86]  A. Sonnenberg,et al.  Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis. , 2012, Neoplasia.

[87]  Gema Moreno-Bueno,et al.  Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET , 2012, Nature Medicine.

[88]  T. Brabletz.  To differentiate or not — routes towards metastasis , 2012, Nature Reviews Cancer.

[89]  L. Cingolani,et al.  Tetraspanins: Interactions and interplay with integrins. , 2012, The international journal of biochemistry & cell biology.

[90]  S. Granter,et al.  Tetraspanin CD151 plays a key role in skin squamous cell carcinoma , 2012, Oncogene.

[91]  C. Gondi,et al.  Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin‐mediated cell adhesion and invasion in glioma , 2012, Molecular carcinogenesis.

[92]  A. Eichmann,et al.  VEGF signaling inside vascular endothelial cells and beyond. , 2012, Current opinion in cell biology.

[93]  D. Golan,et al.  CD151 restricts the α6 integrin diffusion mode , 2012, Journal of Cell Science.

[94]  Charles P. Lin,et al.  P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment. , 2012, Blood.

[95]  M. Tomlinson,et al.  The emerging role of tetraspanin microdomains on endothelial cells. , 2011, Biochemical Society transactions.

[96]  J. Vannier,et al.  A truncated form of CD9-partner 1 (CD9P-1), GS-168AT2, potently inhibits in vivo tumour-induced angiogenesis and tumour growth , 2011, British Journal of Cancer.

[97]  Kutlu G. Elpek,et al.  Diminished metastasis in tetraspanin CD151-knockout mice. , 2011, Blood.

[98]  M. Yáñez-Mó,et al.  Functional interplay between tetraspanins and proteases , 2011, Cellular and Molecular Life Sciences.

[99]  Jia Fan,et al.  CD151 amplifies signaling by integrin α6β1 to PI3K and induces the epithelial-mesenchymal transition in HCC cells. , 2011, Gastroenterology.

[100]  M. Hemler,et al.  Tetraspanin protein contributions to cancer. , 2011, Biochemical Society transactions.

[101]  M. Yáñez-Mó,et al.  The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9 , 2011, Cellular and Molecular Life Sciences.

[102]  F. Berditchevski,et al.  Tetraspanins in human epithelial malignancies , 2011, The Journal of pathology.

[103]  F. Berditchevski,et al.  Tetraspanin CD151 regulates growth of mammary epithelial cells in three-dimensional extracellular matrix: implication for mammary ductal carcinoma in situ. , 2010, Cancer research.

[104]  K. Preissner,et al.  Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. , 2010, Cancer research.

[105]  C. Stipp.  Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets , 2010, Expert Reviews in Molecular Medicine.

[106]  M. Hemler,et al.  Tetraspanin12 regulates ADAM10‐dependent cleavage of amyloid precursor protein , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[107]  J. Gu,et al.  Roles of Laminin-332 and α6β4 Integrin in Tumor Progression , 2009 .

[108]  L. Jennings,et al.  Tetraspanins and vascular functions. , 2009, Cardiovascular research.

[109]  Eric Rubinstein,et al.  Lateral organization of membrane proteins: tetraspanins spin their web. , 2009, The Biochemical journal.

[110]  K. Cortese,et al.  Clathrin and LRP-1-Independent Constitutive Endocytosis and Recycling of uPAR , 2008, PloS one.

[111]  E. Gratton,et al.  Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms , 2008, The Journal of cell biology.

[112]  Yuetsu Tanaka,et al.  A CD63 Mutant Inhibits T‐cell Tropic Human Immunodeficiency Virus Type 1 Entry by Disrupting CXCR4 Trafficking to the Plasma Membrane , 2008, Traffic.

[113]  P. Comoglio,et al.  The MET receptor tyrosine kinase in invasion and metastasis , 2007, Journal of cellular physiology.

[114]  S. Kimura,et al.  CD151 dynamics in carcinoma–stroma interaction: integrin expression, adhesion strength and proteolytic activity , 2007, Laboratory Investigation.

[115]  C. Butterfield,et al.  Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. , 2007, Blood.

[116]  E. Odintsova,et al.  Tetraspanins as Regulators of Protein Trafficking , 2007, Traffic.

[117]  M. Zöller,et al.  Systemic induction of the angiogenesis switch by the tetraspanin D6.1A/CO-029. , 2006, Cancer research.

[118]  K. Nakashiro,et al.  CD151 forms a functional complex with c-Met in human salivary gland cancer cells. , 2005, Biochemical and biophysical research communications.

[119]  M. Hemler.  Tetraspanin functions and associated microdomains , 2005, Nature Reviews Molecular Cell Biology.

[120]  P. Han,et al.  Role of beta(1)-integrins and their associated tetraspanin molecules in fibronectin-enhanced megakaryopoiesis. , 2004, Cytotherapy.

[121]  M. Wright,et al.  Characterization of Mice Lacking the Tetraspanin Superfamily Member CD151 , 2004, Molecular and Cellular Biology.

[122]  T. V. Kolesnikova,et al.  Functional domains in tetraspanin proteins. , 2003, Trends in biochemical sciences.

[123]  B. Hoffman,et al.  Assembly Cho Cell Adhesion to Fibronectin and Fibronectin Pericellular Matrix Identification of Cd9 Extracellular Domains Important in Regulation Of , 2022 .

[124]  Jin Chen,et al.  The ephrins and Eph receptors in angiogenesis. , 2002, Cytokine & growth factor reviews.

[125]  M. Yáñez-Mó,et al.  Regulatory role of tetraspanin CD9 in tumor-endothelial cell interaction during transendothelial invasion of melanoma cells. , 2001, Blood.

[126]  F. Berditchevski.  Complexes of tetraspanins with integrins: more than meets the eye. , 2001, Journal of cell science.

[127]  M. Le Bousse-Kerdilès,et al.  CD9 and megakaryocyte differentiation. , 2001, Blood.

[128]  D. Azorsa,et al.  CD9 participates in endothelial cell migration during in vitro wound repair. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[129]  M. Schwab,et al.  Association Between the Rat Homologue of CO-029, a Metastasis-associated Tetraspanin Molecule and Consumption Coagulopathy , 1998, The Journal of cell biology.

[130]  S. Levy,et al.  The tetraspanin superfamily: molecular facilitators , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[131]  J. Gimble,et al.  Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures. , 1996, Blood.

[132]  S. K. Boey,et al.  Plasma Membrane , 2005 .

[133]  A. Sonnenberg,et al.  The opposing roles of laminin-binding integrins in cancer. , 2017, Matrix biology : journal of the International Society for Matrix Biology.

[134]  T. Whiteside.  Tumor-Derived Exosomes and Their Role in Cancer Progression. , 2016, Advances in clinical chemistry.

[135]  Y. Joo,et al.  Impact of KITENIN on tumor angiogenesis and lymphangiogenesis in colorectal cancer. , 2016, Oncology reports.

[136]  N. Varin‐Blank,et al.  CD9, a key actor in the dissemination of lymphoblastic leukemia, modulating CXCR4-mediated migration via RAC1 signaling. , 2015, Blood.

[137]  E. Williams,et al.  CD151 is associated with prostate cancer cell invasion and lymphangiogenesis in vivo. , 2014, Oncology reports.

[138]  R. Kordek,et al.  CD151 in cancer progression and metastasis: a complex scenario , 2014, Laboratory Investigation.

[139]  A. Abdel‐Mageed,et al.  Tumor-derived exosomes in oncogenic reprogramming and cancer progression , 2014, Cellular and Molecular Life Sciences.

[140]  M. Record,et al.  Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. , 2014, Biochimica et biophysica acta.

[141]  M. Shibuya,et al.  Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases. , 2013, Journal of biochemistry.

[142]  I. Nazarenko,et al.  Activation-induced internalization differs for the tetraspanins CD9 and Tspan8: Impact on tumor cell motility. , 2011, The international journal of biochemistry & cell biology.

[143]  J. Gu,et al.  Roles of laminin-332 and alpha6beta4 integrin in tumor progression. , 2009, Mini reviews in medicinal chemistry.

[144]  M. Zöller.  Tetraspanins: push and pull in suppressing and promoting metastasis , 2009, Nature Reviews Cancer.