Identification of eIF6 as a prognostic factor that drives tumor progression and predicts arsenic trioxide efficacy in lung adenocarcinoma

[1]  Song Gao,et al.  BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α Phosphorylation. , 2021, Gastroenterology.

[2]  Linzhi Han,et al.  Tumor stemness and immune infiltration synergistically predict response of radiotherapy or immunotherapy and relapse in lung adenocarcinoma , 2021, Cancer medicine.

[3]  Qifeng Yang,et al.  Circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating Wnt/beta-catenin pathway. , 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

[4]  S. Biffo,et al.  Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma , 2021, Nature Communications.

[5]  Yung-An Tsou,et al.  Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model , 2021, Frontiers in Cell and Developmental Biology.

[6]  F. Aqil,et al.  Exosome-mediated delivery of RNA and DNA for gene therapy. , 2021, Cancer letters.

[7]  H. Ji,et al.  Nanog maintains stemness of Lkb1‐deficient lung adenocarcinoma and prevents gastric differentiation , 2021, EMBO molecular medicine.

[8]  B. Xiao,et al.  tRNA-derived fragments: Mechanisms underlying their regulation of gene expression and potential applications as therapeutic targets in cancers and virus infections , 2021, Theranostics.

[9]  Yanjing Li,et al.  Systematic Analysis of Expression Profiles and Prognostic Significance for FAM83 Family in Non-small-Cell Lung Cancer , 2020, Frontiers in Molecular Biosciences.

[10]  C. Rudin,et al.  Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer , 2020, Cell reports.

[11]  Tianrui Xu,et al.  Eukaryotic translation initiation factors as promising targets in cancer therapy , 2020, Cell Communication and Signaling.

[12]  M. Sos,et al.  The next tier of EGFR resistance mutations in lung cancer , 2020, Oncogene.

[13]  Shiming Yang,et al.  Translation of noncoding RNAs and cancer. , 2020, Cancer letters.

[14]  Hong Shen,et al.  eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway , 2020, Journal of Translational Medicine.

[15]  E. Feuer,et al.  The Effect of Advances in Lung-Cancer Treatment on Population Mortality. , 2020, The New England journal of medicine.

[16]  Junming Xu,et al.  Integrative Proteomic Characterization of Human Lung Adenocarcinoma , 2020, Cell.

[17]  W. Weichert,et al.  New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma , 2020, AntiCancer Research.

[18]  W. Xue,et al.  Hypoxia-induced GBE1 expression promotes tumor progression through metabolic reprogramming in lung adenocarcinoma , 2020, Signal Transduction and Targeted Therapy.

[19]  Yiyan Lei,et al.  HIF-1ɑ-regulated miR-1275 maintains stem cell-like phenotypes and promotes the progression of LUAD by simultaneously activating Wnt/β-catenin and Notch signaling , 2020, Theranostics.

[20]  Kwok-Kin Wong,et al.  Notch inhibition overcomes resistance to Tyrosine Kinase Inhibitors in EGFR-driven lung adenocarcinoma. , 2019, The Journal of clinical investigation.

[21]  G. Freeman,et al.  In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma. , 2019, Cancer discovery.

[22]  Gregory Riely,et al.  Systemic Therapy for Locally Advanced and Metastatic Non-Small Cell Lung Cancer: A Review. , 2019, JAMA.

[23]  Meijin Huang,et al.  eIF6 Promotes Colorectal Cancer Proliferation and Invasion by Regulating AKT-Related Signaling Pathways. , 2019, Journal of biomedical nanotechnology.

[24]  Bradley P. Coe,et al.  Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR‐Mediated Lung Tumorigenesis , 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[25]  Guanming Lu,et al.  Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis , 2018, Journal of experimental & clinical cancer research : CR.

[26]  N. Sonenberg,et al.  Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma , 2018, Nature Medicine.

[27]  G. J. Yoshida.  Emerging roles of Myc in stem cell biology and novel tumor therapies , 2018, Journal of experimental & clinical cancer research : CR.

[28]  L. Mutti,et al.  Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo , 2015, Oncotarget.

[29]  Michael Kahn,et al.  Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update , 2015, Nature Reviews Clinical Oncology.

[30]  P. Londei,et al.  eIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteins , 2015, BMC Cancer.

[31]  Michael L. Gatza,et al.  An integrated genomics approach identifies drivers of proliferation in luminal subtype human breast cancer , 2014, Nature Genetics.

[32]  Konstantinos J. Mavrakis,et al.  RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer , 2014, Nature.

[33]  Y. Fernández,et al.  Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1 , 2014, Oncogene.

[34]  S. Biffo,et al.  Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation , 2009, EMBO reports.

[35]  S. Biffo,et al.  Expression of a highly conserved protein, p27BBP, during the progression of human colorectal cancer. , 2000, Cancer research.

[36]  Xiangying Meng,et al.  Boosting visible-light hydrogen evolution of covalent-organic frameworks by introducing Ni-based noble metal-free co-catalyst , 2020 .

[37]  David M Jablons,et al.  Lung Cancer Staging and Prognosis. , 2016, Cancer treatment and research.