Depth of interocular suppression associated with continuous flash suppression, flash suppression, and binocular rivalry.

When conflicting images are presented to the corresponding regions of the two eyes, only one image may be consciously perceived. In binocular rivalry (BR), two images alternate in phenomenal visibility; even a salient image is eventually suppressed by an image of low saliency. Recently, N. Tsuchiya and C. Koch (2005) reported a technique called continuous flash suppression (CFS), extending the suppression duration more than 10-fold. Here, we investigated the depth of this prolonged form of interocular suppression as well as conventional BR and flash suppression (FS) using a probe detection task. Compared to monocular viewing condition, CFS elevated detection thresholds more than 20-fold, whereas BR did so by 3-fold. In subsequent experiments, we dissected CFS into several components. By manipulating the number and timing of flashes with respect to the probe, we found that the stronger suppression in CFS is not due to summation between BR and FS but is caused by the summation of the suppression due to multiple flashes. Our results support the view that CFS is not a stronger version of BR but is due to the accumulated suppressive effects of multiple flashes.

[1]  N. Logothetis,et al.  Neuronal correlates of subjective visual perception. , 1989, Science.

[2]  Susana Martinez-Conde,et al.  Dichoptic Visual Masking Reveals that Early Binocular Neurons Exhibit Weak Interocular Suppression: Implications for Binocular Vision and Visual Awareness , 2004, Journal of Cognitive Neuroscience.

[3]  David A. Leopold,et al.  Generalized Flash Suppression of Salient Visual Targets , 2003, Neuron.

[4]  C. Koch.  The quest for consciousness : a neurobiological approach , 2004 .

[5]  N. Logothetis,et al.  Visual competition , 2002, Nature Reviews Neuroscience.

[6]  Hugh R Wilson,et al.  Computational evidence for a rivalry hierarchy in vision , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[7]  Stephen L Macknik,et al.  Visibility, visual awareness, and visual masking of simple unattended targets are confined to areas in the occipital cortex beyond human V1/V2. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[8]  N. Logothetis,et al.  Activity changes in early visual cortex reflect monkeys' percepts during binocular rivalry , 1996, Nature.

[9]  B G Breitmeyer,et al.  Metacontrast investigations of sustained-transient channel inhibitory interactions. , 1981, Journal of experimental psychology. Human perception and performance.

[10]  Timothy J Andrews,et al.  Binocular rivalry and visual awareness , 2001, Trends in Cognitive Sciences.

[11]  Michael S. Loop,et al.  Visual suppression and its effect upon color and luminance sensitivity , 1994, Vision Research.

[12]  P. H. Schiller,et al.  MONOPTIC AND DICHOPTIC VISUAL MASKING BY PATTERNS AND FLASHES. , 1965, Journal of experimental psychology.

[13]  K. Nakayama,et al.  Binocular Rivalry and Visual Awareness in Human Extrastriate Cortex , 1998, Neuron.

[14]  F. Tong,et al.  Can attention selectively bias bistable perception? Differences between binocular rivalry and ambiguous figures. , 2004, Journal of vision.

[15]  D H Brainard,et al.  The Psychophysics Toolbox. , 1997, Spatial vision.

[16]  R. Blake,et al.  Spatial zones of binocular rivalry in central and peripheral vision , 1992, Visual Neuroscience.

[17]  David L. Sheinberg,et al.  The role of temporal cortical areas in perceptual organization. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[18]  P. Wenderoth,et al.  The depth and selectivity of suppression in binocular rivalry , 2001, Perception & psychophysics.

[19]  G. Rees,et al.  Neural correlates of perceptual rivalry in the human brain. , 1998, Science.

[20]  Sabine Kastner,et al.  Neural correlates of binocular rivalry in the human lateral geniculate nucleus , 2005, Nature Neuroscience.

[21]  D N Robinson,et al.  Disinhibition of Visually Masked Stimuli , 1966, Science.

[22]  Hideko F. Norman,et al.  The Temporal Course of Suppression during Binocular Rivalry , 2000, Perception.

[23]  G. Rees,et al.  Predicting the Stream of Consciousness from Activity in Human Visual Cortex , 2005, Current Biology.

[24]  S L Macknik,et al.  The role of spatiotemporal edges in visibility and visual masking. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[25]  R. Blake,et al.  V1 activity is reduced during binocular rivalry. , 2002, Journal of vision.

[26]  A. Sanders.  Attention and performance III : proceedings of a symposium on attention and performance, held in Soesterberg August 4-8,1969, under the auspices of the Institute for Perception RVO-TNO, Soesterberg, the Netherlands , 1970 .

[27]  M. Hollins,et al.  Rivalry target luminance does not affect suppression depth , 1981, Perception & psychophysics.

[28]  P. Walker.  Stochastic properties of binocular rivalry alternations , 1975 .

[29]  H. Helmholtz.  Helmholtz's Treatise on Physiological Optics , 1963 .

[30]  Adam P. Morris,et al.  Amygdala Responses to Fearful and Happy Facial Expressions under Conditions of Binocular Suppression , 2004, The Journal of Neuroscience.

[31]  Christopher D. Frith.  The Quest for Consciousness: A Neurobiological Approach , 2005 .

[32]  C. Koch,et al.  Continuous flash suppression reduces negative afterimages , 2005, Nature Neuroscience.

[33]  R. Fox,et al.  Binocular rivalry and reciprocal inhibition , 1969 .

[34]  R. Blake,et al.  On the inhibitory nature of binocular rivalry suppression. , 1979, Journal of experimental psychology. Human perception and performance.

[35]  D. Heeger,et al.  Neuronal activity in human primary visual cortex correlates with perception during binocular rivalry , 2000, Nature Neuroscience.

[36]  R. Fox,et al.  Independence between binocular rivalry suppression duration and magnitude of suppression. , 1972, Journal of experimental psychology.

[37]  Stephen A. Engel,et al.  Interocular rivalry revealed in the human cortical blind-spot representation , 2001, Nature.

[38]  Carson C. Chow,et al.  A Spiking Neuron Model for Binocular Rivalry , 2004, Journal of Computational Neuroscience.

[39]  R. Deichmann,et al.  Eye-specific effects of binocular rivalry in the human lateral geniculate nucleus , 2005, Nature.

[40]  Jeremy M. Wolfe,et al.  Reversing ocular dominance and suppression in a single flash , 1984, Vision Research.

[41]  Randolph Blake,et al.  Traveling waves of activity in primary visual cortex during binocular rivalry , 2005, Nature Neuroscience.

[42]  W N Dember,et al.  Recovery of Masked Visual Targets by Inhibition of the Masking Stimulus , 1967, Science.

[43]  R. Blake,et al.  Preserved gain control for luminance contrast during binocular rivalry suppression , 2004, Vision Research.

[44]  Randolph Blake,et al.  Psychophysical magic: rendering the visible ‘invisible’ , 2005, Trends in Cognitive Sciences.

[45]  H. Levitt.  Transformed up-down methods in psychoacoustics. , 1971, The Journal of the Acoustical Society of America.

[46]  Brian N. Pasley,et al.  Subcortical Discrimination of Unperceived Objects during Binocular Rivalry , 2004, Neuron.

[47]  R. Fox,et al.  Increment detection thresholds during binocular rivalry suppression , 1970 .

[48]  Jiro Gyoba,et al.  Selective Attention to Stimulus Features Modulates Interocular Suppression , 2002, Perception.

[49]  F. Fang,et al.  Cortical responses to invisible objects in the human dorsal and ventral pathways , 2005, Nature Neuroscience.

[50]  M. Lankheet,et al.  Unraveling adaptation and mutual inhibition in perceptual rivalry. , 2006, Journal of vision.

[51]  Bruno G. Breitmeyer,et al.  Visual masking : an integrative approach , 1984 .

[52]  David Alais,et al.  Increasing depth of binocular rivalry suppression along two visual pathways , 2003, Vision Research.

[53]  Zijiang J. He,et al.  Binocular Rivalry and Visual Awareness: The Role of Attention , 1999, Perception.

[54]  R. Blake,et al.  The Interaction between Binocular Rivalry and Negative Afterimages , 2005, Current Biology.

[55]  C W Tyler,et al.  Colour bit-stealing to enhance the luminance resolution of digital displays on a single pixel basis. , 1997, Spatial vision.

[56]  R. Blake,et al.  Temporal perturbations of binocular rivalry , 1990, Perception & psychophysics.

[57]  G. Rees,et al.  Covariation of activity in visual and prefrontal cortex associated with subjective visual perception. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[58]  Randolph Blake,et al.  Exogenous attention and endogenous attention influence initial dominance in binocular rivalry , 2006, Vision Research.

[59]  M. Livingstone,et al.  Neuronal correlates of visibility and invisibility in the primate visual system , 1998, Nature Neuroscience.

[60]  Jude F. Mitchell,et al.  Object-based attention determines dominance in binocular rivalry , 2004, Nature.

[61]  Christof Koch,et al.  Face Adaptation Depends on Seeing the Face , 2005, Neuron.