Efficient gene-specific expression of Cre recombinase in the mouse embryo by targeted insertion of a novel IRES-Cre cassette into endogenous loci
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[1] K. Chébli,et al. A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability , 1998, Molecular and Cellular Biology.
[2] S. O’Gorman,et al. Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[3] B. Rosen,et al. Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice. , 1997, Genome research.
[4] David J. Anderson,et al. Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain , 1996, Cell.
[5] S. Tonegawa,et al. The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory , 1996, Cell.
[6] A. Flenniken,et al. Distinct and overlapping expression patterns of ligands for Eph-related receptor tyrosine kinases during mouse embryogenesis. , 1996, Developmental biology.
[7] A. Lumsden,et al. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny. , 1996, Development.
[8] T. Pawson,et al. Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System , 1996, Cell.
[9] A. Flenniken,et al. Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis , 1996, Neuron.
[10] J. Collignon,et al. Relationship between asymmetric nodal expression and the direction of embryonic turning , 1996, Nature.
[11] A. Reith,et al. Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion. , 1996, Oncogene.
[12] D. Wilkinson,et al. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. , 1995, Development.
[13] J. Flanagan,et al. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites , 1995, Molecular and cellular biology.
[14] John G Flanagan,et al. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map , 1995, Cell.
[15] Jürgen Löschinger,et al. In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases , 1995, Cell.
[16] T Pawson,et al. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. , 1994, Science.
[17] K. Rajewsky,et al. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. , 1994, Science.
[18] D. Wilkinson,et al. Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain , 1994, Mechanisms of Development.
[19] A. Reith,et al. The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development. , 1994, Oncogene.
[20] J. Nichols,et al. Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[21] E. Robertson,et al. The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development , 1994, Mechanisms of Development.
[22] T. Pawson,et al. Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis. , 1994, Oncogene.
[23] E. Robertson,et al. Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin. , 1993, Development.
[24] K. Rajewsky,et al. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting , 1993, Cell.
[25] K. Rajewsky,et al. Shutdown of class switch recombination by deletion of a switch region control element , 1993, Science.
[26] D. Wilkinson,et al. A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm. , 1992, Development.
[27] V. Agol,et al. Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA , 1992, Cell.
[28] J. Sanes,et al. The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos , 1991, Molecular and cellular biology.
[29] A. Graham,et al. Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo. , 1991, Development.
[30] R. Pedersen,et al. Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. , 1991, Development.
[31] Philippe Soriano,et al. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. , 1991, Genes & development.
[32] J. Seidman,et al. Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[33] G. Wahl,et al. Recombinase-mediated gene activation and site-specific integration in mammalian cells. , 1991, Science.
[34] E. Myers,et al. Basic local alignment search tool. , 1990, Journal of molecular biology.
[35] E. Wimmer,et al. Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. , 1990, Genes & development.
[36] P. Tam. Regionalisation of the mouse embryonic ectoderm: allocation of prospective ectodermal tissues during gastrulation. , 1989, Development.
[37] E. Wimmer,et al. Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo , 1989, Journal of virology.
[38] R. Beddington,et al. An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo. , 1989, Development.
[39] N. Henderson,et al. Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome. , 1989, Nucleic acids research.
[40] E. Wimmer,et al. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation , 1988, Journal of virology.
[41] N. Henderson,et al. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[42] A. Bradley. Production and analysis of chimeric mice , 1987 .
[43] A. Bradley,et al. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector , 1986, Nature.
[44] C. Waddington. Mechanisms of Development , 1955, Nature.
[45] J. Mattick,et al. Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif. , 1996, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.
[46] R. Pedersen,et al. Clonal analysis of cell fate during gastrulation and early neurulation in the mouse. , 1992, Ciba Foundation symposium.
[47] T. Doetschman,et al. Gene targeting in embryonic stem cells. , 1991, Biotechnology.
[48] Ucrf Developmental,et al. An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo , 1989 .
[49] R. Beddington,et al. The formation of mesodermal tissues in the mouse embryo during gastrulation and early organogenesis. , 1987, Development.
[50] E. Robertson. Teratocarcinomas and embryonic stem cells : a practical approach , 1987 .