Sensing with TRP channels

[1]  A. Patapoutian,et al.  The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin , 2005, Current Biology.

[2]  I. Michailidis,et al.  PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain , 2005, Nature Neuroscience.

[3]  K. Schulten,et al.  In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats. , 2005, Structure.

[4]  A. Moqrich,et al.  Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin , 2005, Science.

[5]  A. Randall,et al.  Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) , 2005, British journal of pharmacology.

[6]  B. Kaang,et al.  Pyrexia is a new thermal transient receptor potential channel endowing tolerance to high temperatures in Drosophila melanogaster , 2005, Nature Genetics.

[7]  Craig Montell,et al.  The TRP Superfamily of Cation Channels , 2005, Science's STKE.

[8]  Beiying Liu,et al.  Functional Control of Cold- and Menthol-Sensitive TRPM8 Ion Channels by Phosphatidylinositol 4,5-Bisphosphate , 2005, The Journal of Neuroscience.

[9]  P. Garrity,et al.  The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis. , 2005, Genes & development.

[10]  M. Caterina,et al.  Altered Thermal Selection Behavior in Mice Lacking Transient Receptor Potential Vanilloid 4 , 2005, The Journal of Neuroscience.

[11]  A. Kurosky,et al.  TRPC1 forms the stretch-activated cation channel in vertebrate cells , 2005, Nature Cell Biology.

[12]  Heidi L. Rehm,et al.  TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells , 2004, Nature.

[13]  R. Penner,et al.  The TRPM ion channel subfamily: molecular, biophysical and functional features. , 2004, Trends in pharmacological sciences.

[14]  A. Patapoutian.  Faculty Opinions recommendation of Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8. , 2004 .

[15]  R. Latorre,et al.  Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[16]  B. Nilius,et al.  Invertebrate TRP proteins as functional models for mammalian channels , 2004, Pflügers Archiv.

[17]  D. Julius,et al.  The Super-Cooling Agent Icilin Reveals a Mechanism of Coincidence Detection by a Temperature-Sensitive TRP Channel , 2004, Neuron.

[18]  R. MacKinnon.  Potassium channels and the atomic basis of selective ion conduction (Nobel Lecture). , 2004 .

[19]  Bernd Nilius,et al.  The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels , 2004, Nature.

[20]  B. Nilius,et al.  Outer Pore Architecture of a Ca2+-selective TRP Channel* , 2004, Journal of Biological Chemistry.

[21]  A. Patapoutian,et al.  Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin , 2004, Neuron.

[22]  Jonathon Howard,et al.  Hypothesis: A helix of ankyrin repeats of the NOMPC-TRP ion channel is the gating spring of mechanoreceptors , 2004, Current Biology.

[23]  D. McKemy,et al.  Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 , 2004, Nature.

[24]  H. Watanabe,et al.  Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4 , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[25]  David E. Clapham,et al.  TRP channels as cellular sensors , 2003, Nature.

[26]  David M Tobin,et al.  Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Shigekawa,et al.  TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes , 2003, Circulation research.

[28]  J. Friedman,et al.  Abnormal osmotic regulation in trpv4-/- mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[29]  B. Nilius,et al.  Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels , 2003, Nature.

[30]  Rainer W Friedrich,et al.  NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction , 2003, Science.

[31]  Maurice J. Kernan,et al.  A TRPV family ion channel required for hearing in Drosophila , 2003, Nature.

[32]  A. Patapoutian,et al.  ThermoTRP channels and beyond: mechanisms of temperature sensation , 2003, Nature Reviews Neuroscience.

[33]  M. Imai,et al.  Impaired osmotic sensation in mice lacking TRPV4. , 2003, American journal of physiology. Cell physiology.

[34]  K. Kodaira,et al.  Impaired Pressure Sensation in Mice Lacking TRPV4* , 2003, Journal of Biological Chemistry.

[35]  A. Patapoutian,et al.  Ion channels: Opposite thermosensor in fruitfly and mouse , 2003, Nature.

[36]  G. Schultz,et al.  Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3* , 2003, Journal of Biological Chemistry.

[37]  D. Julius,et al.  A Modular PIP2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity , 2003, Science.

[38]  Gilles Laurent,et al.  painless, a Drosophila Gene Essential for Nociception , 2003, Cell.

[39]  Peter McIntyre,et al.  ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures , 2003, Cell.

[40]  B. Nilius,et al.  Homo‐ and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6 , 2003, The EMBO journal.

[41]  Jing Zhou,et al.  Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells , 2003, Nature Genetics.

[42]  B. Nilius,et al.  Heat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial Cells* , 2002, The Journal of Biological Chemistry.

[43]  Sunghoon Kim,et al.  Agonist Recognition Sites in the Cytosolic Tails of Vanilloid Receptor 1* , 2002, The Journal of Biological Chemistry.

[44]  G. Yellen.  The voltage-gated potassium channels and their relatives , 2002, Nature.

[45]  Boris Martinac,et al.  Open channel structure of MscL and the gating mechanism of mechanosensitive channels , 2002, Nature.

[46]  Makoto Tominaga,et al.  Heat-Evoked Activation of the Ion Channel, TRPV4 , 2002, The Journal of Neuroscience.

[47]  P. Anand,et al.  TRPV3 is a temperature-sensitive vanilloid receptor-like protein , 2002, Nature.

[48]  David E. Clapham,et al.  TRPV3 is a calcium-permeable temperature-sensitive cation channel , 2002, Nature.

[49]  John B. Hogenesch,et al.  A Heat-Sensitive TRP Channel Expressed in Keratinocytes , 2002, Science.

[50]  V. Flockerzi,et al.  Activation of TRPV4 Channels (hVRL-2/mTRP12) by Phorbol Derivatives* , 2002, The Journal of Biological Chemistry.

[51]  P. McIntyre,et al.  A TRP Channel that Senses Cold Stimuli and Menthol , 2002, Cell.

[52]  D. McKemy,et al.  Identification of a cold receptor reveals a general role for TRP channels in thermosensation , 2002, Nature.

[53]  S. Somlo,et al.  Polycystin-2 is an intracellular calcium release channel , 2002, Nature Cell Biology.

[54]  David Julius,et al.  Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers , 2002, Cell.

[55]  Craig Montell,et al.  A unified nomenclature for the superfamily of TRP cation channels. , 2002, Molecular cell.

[56]  Roger C. Hardie,et al.  Visual transduction in Drosophila , 2001, Nature.

[57]  A. Basbaum,et al.  Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition , 2001, Nature.

[58]  E. Neher,et al.  Molecular biology meets microelectronics , 2001, Nature Biotechnology.

[59]  M. Freichel,et al.  Trp12, a novel Trp related protein from kidney , 2000, FEBS letters.

[60]  A. Hudspeth,et al.  Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor , 2000, Cell.

[61]  G. Schultz,et al.  OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity , 2000, Nature Cell Biology.

[62]  L. Salkoff,et al.  TRPγ, a Drosophila TRP–Related Subunit, Forms a Regulated Cation Channel with TRPL , 2000, Neuron.

[63]  S. Hwang,et al.  Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[64]  S. Bingham,et al.  Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia , 2000, Nature.

[65]  A I Basbaum,et al.  Impaired nociception and pain sensation in mice lacking the capsaicin receptor. , 2000, Science.

[66]  C. Zuker,et al.  A Drosophila mechanosensory transduction channel. , 2000, Science.

[67]  P. Blumberg,et al.  The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons. , 1999, Molecular pharmacology.

[68]  D. Julius,et al.  Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide , 1999, Nature.

[69]  D. Julius,et al.  A capsaicin-receptor homologue with a high threshold for noxious heat , 1999, Nature.

[70]  Roger C. Hardie,et al.  Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL , 1999, Nature.

[71]  R. Hardie,et al.  In Vivo Analysis of the Drosophila Light-Sensitive Channels, TRP and TRPL , 1997, Neuron.

[72]  Cori Bargmann,et al.  OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans , 1997, The Journal of Neuroscience.

[73]  D. Julius,et al.  The capsaicin receptor: a heat-activated ion channel in the pain pathway , 1997, Nature.

[74]  M. Peyton,et al.  On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[75]  D. Clapham.  TRP Is Cracked but Is CRAC TRP? , 1996, Neuron.

[76]  G. Schultz,et al.  Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion , 1996, Neuron.

[77]  R. Hurst,et al.  trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry , 1996, Cell.

[78]  A. Jeromin,et al.  TRPC1, a human homolog of a Drosophila store-operated channel. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[79]  M. Berridge,et al.  Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues. , 1995, The Biochemical journal.

[80]  R. Hardie,et al.  The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors , 1992, Neuron.

[81]  L. Kelly,et al.  Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene , 1992, Neuron.

[82]  G. Rubin,et al.  Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction , 1989, Neuron.

[83]  B. Hille,et al.  Ionic channels of excitable membranes , 2001 .

[84]  A. Manning,et al.  Abnormal Electroretinogram from a Drosophila Mutant , 1969, Nature.