Luteolin exerts anti-tumor activity through the suppression of epidermal growth factor receptor-mediated pathway in MDA-MB-231 ER-negative breast cancer cells.
暂无分享,去创建一个
[1] X. Ronot,et al. Flavones inhibit the proliferation of human tumor cancer cell lines by inducing apoptosis , 2012, Drug and chemical toxicology.
[2] F. Wang,et al. Suppression of Polo like kinase 1 (PLK1) by p21(Waf1) mediates the p53-dependent prevention of caspase-independent mitotic death. , 2011, Cellular signalling.
[3] L. Pusztai,et al. Gene expression profiling in breast cancer: classification, prognostication, and prediction , 2011, The Lancet.
[4] Min Wang,et al. Luteolin induced G2 phase cell cycle arrest and apoptosis on non-small cell lung cancer cells. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.
[5] W. Krol,et al. The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells. , 2011, International journal of oncology.
[6] A. Saluja,et al. Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. , 2011, Cancer letters.
[7] Haitao Luo,et al. Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway. , 2011, Food chemistry.
[8] Xi-hai Li,et al. Quercetin-mediated apoptosis via activation of the mitochondrial-dependent pathway in MG-63 osteosarcoma cells. , 2011, Molecular medicine reports.
[9] A. Ellington,et al. Inhibition of Cell Proliferation by an Anti-EGFR Aptamer , 2011, PloS one.
[10] Jen-kun Lin,et al. 1,2,3,4,6-penta-O-galloyl-β-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of Skp2 protein. , 2011, Journal of agricultural and food chemistry.
[11] N. Lu,et al. Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. , 2011, Toxicology.
[12] R. Copeland,et al. Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. , 2011, Biochemical and biophysical research communications.
[13] W. Ling,et al. Anticancer Activities of an Anthocyanin-Rich Extract From Black Rice Against Breast Cancer Cells In Vitro and In Vivo , 2010, Nutrition and cancer.
[14] N. Lu,et al. Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells. , 2010, Cancer letters.
[15] M. Vijjeswarapu,et al. Luteolin and gefitinib regulation of EGF signaling pathway and cell cycle pathway genes in PC-3 human prostate cancer cells , 2010, The Journal of Steroid Biochemistry and Molecular Biology.
[16] J. Schlessinger,et al. Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.
[17] K. Strebhardt,et al. Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21WAF1/CIP1 , 2009, Cell cycle.
[18] Yuquan Wei,et al. Cell Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis Induced by Chloroquine in Human Breast Cancer Cell Line Bcap-37 , 2008, Cellular Physiology and Biochemistry.
[19] I. Merfort,et al. Anti-carcinogenic Effects of the Flavonoid Luteolin , 2008, Molecules.
[20] S. Zeng,et al. Intestinal absorption of luteolin from peanut hull extract is more efficient than that from individual pure luteolin. , 2008, Journal of agricultural and food chemistry.
[21] A. Ullrich,et al. Targeting polo-like kinase 1 for cancer therapy , 2006, Nature Reviews Cancer.
[22] S. Lakhani,et al. Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis , 2005, Breast Cancer Research.
[23] Sven Kappel,et al. Conditional inhibition of cancer cell proliferation by tetracycline-responsive, H1 promoter-driven silencing of PLK1 , 2005, Oncogene.
[24] Ching-Shu Lai,et al. Induction of apoptosis by luteolin through cleavage of Bcl-2 family in human leukemia HL-60 cells. , 2005, European journal of pharmacology.
[25] H. Derendorf,et al. Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans. , 2005, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[26] K. Strebhardt,et al. Polo-like kinases and oncogenesis , 2005, Oncogene.
[27] W. Dai. Polo-like kinases, an introduction , 2005, Oncogene.
[28] I. Ellis,et al. Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma , 2004, British Journal of Cancer.
[29] Debajit K. Biswas,et al. NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis , 2004 .
[30] A. Lee,et al. Transinactivation of the epidermal growth factor receptor tyrosine kinase and focal adhesion kinase phosphorylation by dietary flavonoids: effect on invasive potential of human carcinoma cells. , 2004, Biochemical pharmacology.
[31] U. Rodeck,et al. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. , 2003, Cancer research.
[32] Jürgen Bereiter-Hahn,et al. Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells. , 2002, Journal of the National Cancer Institute.
[33] H. Ueda,et al. Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens. , 2002, Biological & pharmaceutical bulletin.
[34] F. Casagrande,et al. Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1. , 2001, Biochemical pharmacology.
[35] Debajit K. Biswas,et al. Epidermal growth factor-induced nuclear factor κB activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells , 2000 .
[36] E. Middleton,et al. Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis‐associated properties in A431 cells overexpressing epidermal growth factor receptor , 1999, British journal of pharmacology.
[37] K. Shimoi,et al. Radioprotective effect of antioxidative flavonoids in γ-ray irradiated mice , 1994 .
[38] T. Karn,et al. Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[39] D. Fabbro,et al. Correlation between hormone dependency and the regulation of epidermal growth factor receptor by tumor promoters in human mammary carcinoma cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.