CRYOPRESERVED PRIMARY HEPATOCYTES AS A CONSTANTLY AVAILABLE IN VITRO MODEL FOR THE EVALUATION OF HUMAN AND ANIMAL DRUG METABOLISM AND ENZYME INDUCTION*
暂无分享,去创建一个
F. Oesch | J. Hengstler | P. Steinberg | D. Utesch | M. Ringel | J G Hengstler | T. Böttger | P Steinberg | F Oesch | K L Platt | N Swales | D Utesch | B Diener | M Ringel | T Fischer | K Biefang | M Gerl | T Böttger | B. Diener | K. Platt | T. Fischer | N. Swales | M. Gerl | K. Biefang | Pablo Steinberg | Karl L. Platt | Thomas Fischer | Th. Böttger | Franz Oesch
[1] G. Siest,et al. UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. , 1983, Biochemical pharmacology.
[2] Walter A. Korfmacher,et al. Metabolism of methapyrilene by Fischer-344 rat and B6C3F1 mouse hepatocytes. , 1992, Xenobiotica; the fate of foreign compounds in biological systems.
[3] B J Blaauboer,et al. Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. , 1991, Biochemical pharmacology.
[4] F. Oesch,et al. A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics. , 1993, Cryobiology.
[5] F. Oesch,et al. Cultures with cryopreserved hepatocytes: applicability for studies of enzyme induction. , 2000, Chemico-biological interactions.
[6] G. L. Kedderis,et al. Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel. , 1999, Chemico-biological interactions.
[7] F. Oesch,et al. Cryopreserved and hypothermically stored rat liver parenchymal cells as metabolizing system in the Salmonella mutagenicity assay. , 1995, Mutation research.
[8] B. Lacarelle,et al. Thawed human hepatocytes in primary culture. , 1992, Cryobiology.
[9] J. Caldwell,et al. Cryopreservation of rat and mouse hepatocytes. I. Comparative viability studies. , 1996, Drug metabolism and disposition: the biological fate of chemicals.
[10] A. Guillouzo,et al. Long-term maintenance of drug-metabolizing enzyme activities in rat hepatocytes after cryopreservation. , 1997, Toxicology and applied pharmacology.
[11] D. Utesch,et al. Metabolic activity of fresh and cryopreserved dog hepatocyte suspensions. , 1998, Xenobiotica; the fate of foreign compounds in biological systems.
[12] F. Oesch,et al. Functional heterogeneity of UDP-glucuronyltransferase in rat tissues. , 1980, Biochemical pharmacology.
[13] K. Carroll,et al. Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes. , 1999, Drug metabolism and disposition: the biological fate of chemicals.
[14] F. Oesch,et al. Drug metabolizing capacity of cryopreserved human, rat, and mouse liver parenchymal cells in suspension. , 1999, Drug Metabolism And Disposition.
[15] F. Oesch,et al. Direct Analysis of Phase I Metabolites, Phenol Sulfates, Glucuronides and Glutathione Conjugates of Benzo[a]pyrene in Freshly Isolated, Hypothermically Stored and Cryopreserved Hepatocytes , 1996 .
[16] A. Guillouzo,et al. Influence of alginate gel entrapment and cryopreservation on survival and xenobiotic metabolism capacity of rat hepatocytes. , 1996, Toxicology and applied pharmacology.
[17] P. Seglen. Preparation of isolated rat liver cells. , 1976, Methods in cell biology.
[18] H. Glatt,et al. Rat hepatocyte-mediated bacterial mutagenicity in relation to the carcinogenic potency of benz(a)anthracene, benzo(a)pyrene, and twenty-five methylated derivatives. , 1987, Cancer research.
[19] F. Schildberg,et al. Cryopreservation of porcine hepatocyte cultures. , 1996, Cryobiology.
[20] Mehmet Toner,et al. A Stable Long‐Term Hepatocyte Culture System for Studies of Physiologic Processes: Cytokine Stimulation of the Acute Phase Response in Rat and Human Hepatocytes , 1992, Biotechnology progress.
[21] M K Bayliss,et al. 7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions. , 1994, Xenobiotica; the fate of foreign compounds in biological systems.
[22] F. Oesch,et al. Characterization of cryopreserved rat liver parenchymal cells by metabolism of diagnostic substrates and activities of related enzymes. , 1992, Biochemical pharmacology.
[23] F. Oesch,et al. Improved sample preparation for the testosterone hydroxylation assay using disposable extraction columns. , 1992, Journal of chromatography.
[24] G Smith,et al. A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. , 1994, Biochemical pharmacology.
[25] M. Grant,et al. Cryopreservation of rat hepatocyte monolayer cultures , 1996, Human & experimental toxicology.
[26] H. Sohn,et al. Modulation of cytochrome P-450 induction by long-term food restriction in male rats. , 1994, Biochemistry and molecular biology international.
[27] J. Caldwell,et al. Cryopreservation of rat and mouse hepatocytes. II. Assessment of metabolic capacity using testosterone metabolism. , 1996, Drug metabolism and disposition: the biological fate of chemicals.
[28] A. Li,et al. Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction. , 1997, Chemico-biological interactions.
[29] H. Roh,et al. Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns. , 1998, Chemico-biological interactions.
[30] M. Cayen,et al. Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice. , 1992, Biochemical pharmacology.
[31] V. Rogiers,et al. Maintenance and induction in co-cultured rat hepatocytes of components of the cytochrome P450-mediated mono-oxygenase. , 1993, Biochemical pharmacology.
[32] J. Silva,et al. Induction of cytochrome-P450 in cryopreserved rat and human hepatocytes. , 1999, Chemico-biological interactions.
[33] A. Li,et al. Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions. , 1997, Advances in pharmacology.