Augmentation of DHCR24 expression by hepatitis C virus infection facilitates viral replication in hepatocytes.
暂无分享,去创建一个
Y. Hirata | N. Funata | M. Kohara | T. Hishima | T. Takano | K. Tsukiyama-Kohara | C. Tateno | M. Sudoh | Y. Hayashi | Yuko Tokunaga | Masaaki Satoh | M. Hayashi
[1] A. Siddiqui,et al. Hepatitis C virus hijacks host lipid metabolism , 2010, Trends in Endocrinology & Metabolism.
[2] Y. Hirata,et al. Hepatitis C Virus Impairs p53 via Persistent Overexpression of 3β-Hydroxysterol Δ24-Reductase* , 2009, The Journal of Biological Chemistry.
[3] R. Cenedella. Cholesterol Synthesis Inhibitor U18666A and the Role of Sterol Metabolism and Trafficking in Numerous Pathophysiological Processes , 2009, Lipids.
[4] A. Lonardo,et al. Statins in liver disease: A molehill, an iceberg, or neither? , 2008, Hepatology.
[5] C. Aston,et al. Fluvastatin Inhibits Hepatitis C Replication in Humans , 2008, The American Journal of Gastroenterology.
[6] Y. Hirata,et al. Serine Palmitoyltransferase Inhibitor Suppresses HCV Replication in a Mouse Model , 2008 .
[7] Y. Inoue,et al. Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection , 2008, Journal of Virology.
[8] M. Kohara,et al. Evaluation of a cyclophilin inhibitor in hepatitis C virus–infected chimeric mice in vivo , 2007, Hepatology.
[9] S. Kuge,et al. Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice. , 2007, Biochemical and biophysical research communications.
[10] M. Honda,et al. Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C , 2006, Hepatology.
[11] K. Naka,et al. Different anti‐HCV profiles of statins and their potential for combination therapy with interferon , 2006, Hepatology.
[12] M. Kohara,et al. Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype , 2006, Gene Therapy.
[13] R. Nitsch,et al. The role of seladin‐1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo , 2006, The EMBO journal.
[14] M. Aoki,et al. Host sphingolipid biosynthesis as a target for hepatitis C virus therapy , 2005, Nature chemical biology.
[15] R. Bartenschlager,et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome , 2005, Nature Medicine.
[16] M. Pierotti,et al. DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress‐induced apoptosis , 2005, International journal of cancer.
[17] F. Chisari,et al. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[18] Chaowei Wu,et al. Regulation of cellular response to oncogenic and oxidative stress by Seladin-1 , 2004, Nature.
[19] T. Asahara,et al. Near completely humanized liver in mice shows human-type metabolic responses to drugs. , 2004, The American journal of pathology.
[20] M. Oulad-Abdelghani,et al. Molecular Characterization of the Microsomal Tamoxifen Binding Site* , 2004, Journal of Biological Chemistry.
[21] M. Lai,et al. Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. , 2004, Virology.
[22] Yutaka Hoshikawa,et al. Activation of the CKI-CDK-Rb-E2F Pathway in Full Genome Hepatitis C Virus-expressing Cells* , 2004, Journal of Biological Chemistry.
[23] P. Einat,et al. Generation of Viable Cholesterol-Free Mice , 2003, Science.
[24] M. Gale,et al. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[25] A. Burroughs,et al. Hepatocellular carcinoma , 2003, The Lancet.
[26] L. Wodicka,et al. Genomic analysis of the host response to hepatitis C virus infection , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[27] Hans R. Waterham,et al. Mutations in the 3β-Hydroxysterol Δ24-Reductase Gene Cause Desmosterolosis, an Autosomal Recessive Disorder of Cholesterol Biosynthesis , 2001 .
[28] D. Tyrrell,et al. Hepatitis C virus replication in mice with chimeric human livers , 2001, Nature Medicine.
[29] R. Nitsch,et al. The Human DIMINUTO/DWARF1 Homolog Seladin-1 Confers Resistance to Alzheimer's Disease-Associated Neurodegeneration and Oxidative Stress , 2000, The Journal of Neuroscience.
[30] R. Kawaguchi,et al. Real-time detection system for quantification of hepatitis C virus genome. , 1999, Gastroenterology.
[31] W. Bowen,et al. 99mTc-labeled sigma-receptor-binding complex: synthesis, characterization, and specific binding to human ductal breast carcinoma (T47D) cells. , 1997, Bioconjugate chemistry.
[32] M. Kohara,et al. Hepatitis C Virus Genotypes 1 and 2 Respond to Interferon-a with Different , 1995 .
[33] H. Tsukuma,et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. , 1993, The New England journal of medicine.
[34] T. Yamane,et al. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. , 1982, Cancer research.
[35] C C Howe,et al. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. , 1980, Science.
[36] R. Cenedella,et al. Induction of chronic epileptiform activity in the rat by an inhibitor of cholesterol synthesis, U18666A , 1978, Brain Research.
[37] P. Vreken,et al. Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis. , 2001, American journal of human genetics.
[38] M. Alter,et al. Epidemiology of Hepatitis C: Geographic Differences and Temporal Trends , 2000, Seminars in liver disease.
[39] A. Shevchenko,et al. Sample preparation methods for mass spectrometric peptide mapping directly from 2-DE gels. , 1999, Methods in molecular biology.
[40] M. Kohara,et al. Hepatitis C virus genotypes 1 and 2 respond to interferon-alpha with different virologic kinetics. , 1995, The Journal of infectious diseases.