25 Tissue engineering: the multidisciplinary epitome of hope and despair

Publisher Summary The processes of tissue regeneration in adult humans are biologically feasible. The development of tissue engineering as a viable industry has to take into account the infrastructure surrounding the new concepts that are involved. There will be a number of critical pragmatic factors that control success. One of the most significant is the situation of unmet clinical need. It is highly unlikely that tissue engineering will succeed, at least initially, if it concentrates on the areas that are already well served with both clinical success and acceptable costs by alternative therapies. With the current models, it has been found that the development of tissue-engineering products requires investments that approach the astronomical amounts normally associated with the pharmaceutical industry but with financial returns more equivalent to those of the lower cost-based medical-device industry. This gap is unsustainable. The problem that this technology has faced is the separation of the tissue-engineering process into discrete phases.

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