Immune regulation of multiple sclerosis.
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[1] R. Spang,et al. T cells become licensed in the lung to enter the central nervous system , 2012, Nature.
[2] H. Hartung,et al. Animal models of multiple sclerosis—Potentials and limitations , 2010, Progress in Neurobiology.
[3] B. Becher,et al. Cytokine networks in multiple sclerosis: lost in translation , 2010, Current opinion in neurology.
[4] S. Hallermann,et al. Cytotoxic CD8+ T Cell–Neuron Interactions: Perforin-Dependent Electrical Silencing Precedes But Is Not Causally Linked to Neuronal Cell Death , 2009, The Journal of Neuroscience.
[5] H. Wekerle,et al. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions , 2009, Nature.
[6] M. Mori,et al. Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system , 2009, Nature Medicine.
[7] G. Krishnamoorthy,et al. Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis , 2009, Nature Medicine.
[8] S. Blystone,et al. Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype , 2009, Laboratory Investigation.
[9] H. Weiner,et al. Novel therapeutic strategies for multiple sclerosis — a multifaceted adversary , 2008, Nature Reviews Drug Discovery.
[10] H. von Büdingen,et al. Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin‐specific antibodies , 2008, European journal of immunology.
[11] L. O’Neill. Primer: Toll-like receptor signaling pathways—what do rheumatologists need to know? , 2008, Nature Clinical Practice Rheumatology.
[12] O. Kämpe,et al. Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis , 2008, European journal of immunology.
[13] F. Zipp,et al. Roles of the kallikrein/kinin system in the adaptive immune system. , 2008, International immunopharmacology.
[14] Lorraine Lau,et al. MMPs in the central nervous system: where the good guys go bad. , 2008, Seminars in cell & developmental biology.
[15] S. Waxman. Mechanisms of Disease: sodium channels and neuroprotection in multiple sclerosis—current status , 2008, Nature Clinical Practice Neurology.
[16] G. Krishnamoorthy,et al. Experimental models of spontaneous autoimmune disease in the central nervous system , 2007, Journal of Molecular Medicine.
[17] R. Hohlfeld,et al. Dual role of inflammation in CNS disease , 2007, Neurology.
[18] F. Zipp,et al. The role of TRAIL/TRAIL receptors in central nervous system pathology. , 2007, Frontiers in bioscience : a journal and virtual library.
[19] F. Zipp,et al. Neuronal damage in brain inflammation. , 2007, Archives of neurology.
[20] K. Toyka,et al. Kinetics and Organ Distribution of IL-17-Producing CD4 Cells in Proteolipid Protein 139–151 Peptide-Induced Experimental Autoimmune Encephalomyelitis of SJL Mice1 , 2007, The Journal of Immunology.
[21] D. Fitzgerald,et al. Cutting Edge: TLR3 Stimulation Suppresses Experimental Autoimmune Encephalomyelitis by Inducing Endogenous IFN-β1 , 2006, The Journal of Immunology.
[22] Frauke Zipp,et al. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases , 2006, Trends in Neurosciences.
[23] F. Zipp,et al. Death Ligands and Autoimmune Demyelination , 2006, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[24] Hans Lassmann,et al. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. , 2006, Brain : a journal of neurology.
[25] R. Ransohoff. EAE: pitfalls outweigh virtues of screening potential treatments for multiple sclerosis. , 2006, Trends in immunology.
[26] E. Frohman,et al. Multiple sclerosis--the plaque and its pathogenesis. , 2006, The New England journal of medicine.
[27] R. Ransohoff,et al. The many roles of chemokines and chemokine receptors in inflammation. , 2006, The New England journal of medicine.
[28] B. Becher,et al. Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. , 2006, The Journal of clinical investigation.
[29] L. Steinman,et al. Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis. , 2005, Trends in immunology.
[30] P. Moynagh. TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway. , 2005, Trends in immunology.
[31] I. Bechmann,et al. Indolamine 2,3‐dioxygenase is expressed in the CNS and down‐regulates autoimmune inflammation , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[32] C. Hunter. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions , 2005, Nature Reviews Immunology.
[33] H. Hartung,et al. Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis , 2005 .
[34] G. Cheng,et al. The host type I interferon response to viral and bacterial infections , 2005, Cell Research.
[35] I. Bechmann,et al. Neuronal Damage in Autoimmune Neuroinflammation Mediated by the Death Ligand TRAIL , 2005, Neuron.
[36] L. Platanias. Mechanisms of type-I- and type-II-interferon-mediated signalling , 2005, Nature Reviews Immunology.
[37] Roland Martin,et al. Immunology of multiple sclerosis. , 2005, Annual review of immunology.
[38] S. Miller,et al. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis , 2005, Nature Medicine.
[39] B. Becher,et al. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis , 2005, Nature Medicine.
[40] B. Segal. CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination , 2005, Journal of the Neurological Sciences.
[41] B. Becher,et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis , 2005, Nature Medicine.
[42] T. Mcclanahan,et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation , 2005, The Journal of experimental medicine.
[43] A. Rosenwald,et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma , 2005, The Journal of experimental medicine.
[44] S. Wahl,et al. Regulatory T cells and transcription factors: gatekeepers in allergic inflammation. , 2004, Current opinion in immunology.
[45] Y. Kooyk,et al. Modelling of multiple sclerosis: lessons learned in a non-human primate , 2004, The Lancet Neurology.
[46] A. Uccelli,et al. Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[47] Roland Martin,et al. Development of biomarkers in multiple sclerosis. , 2004, Brain : a journal of neurology.
[48] B. Serafini,et al. Detection of Ectopic B‐cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis , 2004, Brain pathology.
[49] M. Duddy,et al. Distinct Profiles of Human B Cell Effector Cytokines: A Role in Immune Regulation?1 , 2004, The Journal of Immunology.
[50] F. Zipp,et al. Direct Impact of T Cells on Neurons Revealed by Two-Photon Microscopy in Living Brain Tissue , 2004, The Journal of Neuroscience.
[51] Chulhee Choi,et al. Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses , 2004, Brain Research Reviews.
[52] J. Antel,et al. Vulnerability of Human Neurons to T Cell-Mediated Cytotoxicity1 , 2003, The Journal of Immunology.
[53] W. Shearer,et al. Basic and clinical immunology. , 2003, The Journal of allergy and clinical immunology.
[54] R. Kastelein,et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain , 2003, Nature.
[55] H. Hartung,et al. New concepts in the immunopathogenesis of multiple sclerosis , 2002, Nature Reviews Neuroscience.
[56] B. Weinshenker,et al. Plasma exchange for severe attacks of CNS demyelination: Predictors of response , 2002, Neurology.
[57] B. Trapp,et al. Axon Loss in the Spinal Cord Determines Permanent Neurological Disability in an Animal Model of Multiple Sclerosis , 2002, Journal of neuropathology and experimental neurology.
[58] R. Ransohoff,et al. Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges. , 2001, Archives of neurology.
[59] B. Trapp,et al. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions , 2001, Annals of neurology.
[60] Lawrence Steinman,et al. Multiple sclerosis: a two-stage disease , 2001, Nature Immunology.
[61] R. Gold,et al. Mechanism of action of glucocorticosteroid hormones: possible implications for therapy of neuroimmunological disorders , 2001, Journal of Neuroimmunology.
[62] P. Villoslada,et al. Immune Responses Against the Myelin/Oligodendrocyte Glycoprotein in Experimental Autoimmune Demyelination , 2001, Journal of Clinical Immunology.
[63] R. Egan,et al. Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease , 2001, Respiratory research.
[64] L. Fugger. Human autoimmunity genes in mice. , 2000, Current opinion in immunology.
[65] R B Banati,et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. , 2000, Brain : a journal of neurology.
[66] P. Krammer,et al. CD95's deadly mission in the immune system , 2000, Nature.
[67] M. Hengartner. The biochemistry of apoptosis , 2000, Nature.
[68] J. Frank,et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand , 2000, Nature Medicine.
[69] H. Lassmann,et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. , 2000, The American journal of pathology.
[70] J. Parisi,et al. Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination , 2000, Annals of neurology.
[71] D. Kolson,et al. Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis , 2000, Multiple sclerosis.
[72] A. Zlotnik,et al. Chemokines: a new classification system and their role in immunity. , 2000, Immunity.
[73] J. Cyster,et al. Leukocyte migration: Scent of the T zone , 2000, Current Biology.
[74] M. Weller,et al. Immune (dys)regulation in multiple sclerosis: role of the CD95-CD95 ligand system. , 1999, Immunology today.
[75] S. Hauser,et al. Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: A case for antigen‐specific antibody mediation , 1999, Annals of neurology.
[76] M. Shlomchik,et al. A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus , 1999, The Journal of experimental medicine.
[77] H. Reiber,et al. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis , 1998, Multiple sclerosis.
[78] M. Baggiolini. Chemokines and leukocyte traffic , 1998, Nature.
[79] A. O’Garra,et al. Cytokines induce the development of functionally heterogeneous T helper cell subsets. , 1998, Immunity.
[80] A. Luster,et al. Chemokines--chemotactic cytokines that mediate inflammation. , 1998, The New England journal of medicine.
[81] Voon Wee Yong,et al. Matrix metalloproteinases and diseases of the CNS , 1998, Trends in Neurosciences.
[82] D. Gilden,et al. Restricted use of VH4 Germline segments in an acute multiple sclerosis brain , 1998, Annals of neurology.
[83] Hans Lassmann,et al. T-cell apoptosis in autoimmune diseases: termination of inf lammation in the nervous system and other sites with specialized immune-defense mechanisms , 1997, Trends in Neurosciences.
[84] M. Lambert,et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α , 1997, Nature.
[85] Nicole Nelson,et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells , 1997, Nature.
[86] S. Chandler,et al. Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview , 1997, Journal of Neuroimmunology.
[87] C. Brosnan,et al. Mechanisms of Immune Injury in Multiple Sclerosis , 1996, Brain pathology.
[88] L. Steinman. A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[89] H. Neumann,et al. Induction of MHC class I genes in neurons. , 1995, Science.
[90] B. Durand,et al. Regulation of MHC class II gene expression. , 1995, Immunobiology.
[91] J. Strominger,et al. Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein , 1995, Cell.
[92] J. Antel,et al. Oligodendrocyte lysis by CD4+ T cells independent of tumor necrosis factor , 1994, Annals of neurology.
[93] H. Lassmann,et al. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. , 1988, The American journal of pathology.
[94] C. Froelich. Modulation of the autologous mixed lymphocyte reaction by β-endorphin , 1987, Journal of Neuroimmunology.
[95] H. Lassmann,et al. Cellular immune reactivity within the CNS , 1986, Trends in Neurosciences.
[96] E. Anderson. Hudson et al. , 1977 .
[97] A. Pestronk,et al. Myasthenia gravis: passive transfer from man to mouse , 1975, Science.
[98] P. Y. Paterson. TRANSFER OF ALLERGIC ENCEPHALOMYELITIS IN RATS BY MEANS OF LYMPH NODE CELLS , 1960, The Journal of experimental medicine.
[99] E. Kabat,et al. THE RAPID PRODUCTION OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN RHESUS MONKEYS BY INJECTION OF HETEROLOGOUS AND HOMOLOGOUS BRAIN TISSUE WITH ADJUVANTS , 1946, The Journal of experimental medicine.
[100] S. Khoury,et al. Immunopathogenesis of multiple sclerosis. , 2012, Clinical immunology.
[101] M. Racke,et al. Toll-like receptors in multiple sclerosis. , 2009, Current topics in microbiology and immunology.
[102] J. Newcombe,et al. Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. , 2006, Brain : a journal of neurology.
[103] R. Medzhitov,et al. Toll-like receptors: linking innate and adaptive immunity. , 2004, Microbes and infection.
[104] U. Utz,et al. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. , 2003, Brain : a journal of neurology.
[105] C. Mackay,et al. Chemoattractant receptors and immune responses , 1999 .
[106] D. Chao,et al. BCL-2 family: regulators of cell death. , 1998, Annual review of immunology.
[107] B. Trapp,et al. Chemokines and chemokine receptors in model neurological pathologies: molecular and immunocytochemical approaches. , 1997, Methods in enzymology.
[108] H. Birkedal‐Hansen. Proteolytic remodeling of extracellular matrix. , 1995, Current opinion in cell biology.
[109] A. Lanzavecchia,et al. Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. , 1990, Annual review of immunology.
[110] I. Cohen,et al. The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis , 1981, European journal of immunology.