Differential and epigenetic gene expression profiling identifies frequent disruption of the RELN pathway in pancreatic cancers.
暂无分享,去创建一个
Michael Goggins | Norihiro Sato | M. Goggins | N. Sato | N. Fukushima | R. Chang | H. Matsubayashi | Noriyoshi Fukushima | Hiroyuki Matsubayashi | Rubens Chang | Rubens Chang
[1] A. Guidotti,et al. DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[2] U. Germing,et al. Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid. , 2004, Blood.
[3] C. Iacobuzio-Donahue,et al. Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. , 2003, Cancer research.
[4] S. Minucci,et al. Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor , 2002, Science.
[5] S. Faraone,et al. Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: A preliminary report , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[6] J. Cameron,et al. The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[7] A. Guidotti,et al. DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[8] P. Laird. Early detection: The power and the promise of DNA methylation markers , 2003, Nature Reviews Cancer.
[9] R H Hruban,et al. Hypermethylation of multiple genes in pancreatic adenocarcinoma. , 2000, Cancer research.
[10] M. Paz,et al. Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. , 2003, Human molecular genetics.
[11] M. Tsao,et al. Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16. , 1996, The American journal of pathology.
[12] T. Yeatman,et al. Clusterin-Mediated Apoptosis Is Regulated by Adenomatous Polyposis Coli and Is p21 Dependent but p53 Independent , 2004, Cancer Research.
[13] M. Goggins,et al. Epigenetic Down-Regulation of CDKN1C/p57KIP2 in Pancreatic Ductal Neoplasms Identified by Gene Expression Profiling , 2005, Clinical Cancer Research.
[14] Joachim Herz,et al. Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation , 1999, Neuron.
[15] M. Toyota,et al. Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors , 2002, Oncogene.
[16] A. Guidotti,et al. Reelin promoter hypermethylation in schizophrenia. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[17] H. Bock,et al. Reelin-mediated Signaling Locally Regulates Protein Kinase B/Akt and Glycogen Synthase Kinase 3β* , 2002, The Journal of Biological Chemistry.
[18] J. Cameron,et al. Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas. , 2004, The American journal of pathology.
[19] R. Hruban,et al. SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor–stromal interactions , 2003, Oncogene.
[20] T. Curran,et al. Role of the reelin signaling pathway in central nervous system development. , 2001, Annual review of neuroscience.
[21] F. Sato,et al. Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. , 2002, Cancer cell.
[22] John Shelton,et al. Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2 , 1999, Cell.
[23] Y. Yarden,et al. Csk Homologous Kinase, a Novel Signaling Molecule, Directly Associates with the Activated ErbB-2 Receptor in Breast Cancer Cells and Inhibits Their Proliferation* , 1998, The Journal of Biological Chemistry.
[24] Ping Zhu,et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells , 2001, The EMBO journal.
[25] Victor X Jin,et al. Loss of Estrogen Receptor Signaling Triggers Epigenetic Silencing of Downstream Targets in Breast Cancer , 2004, Cancer Research.
[26] P. Marks,et al. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors , 1999, Nature.
[27] M. Goggins. Molecular markers of early pancreatic cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] P. Marks,et al. Histone deacetylase inhibitors: from target to clinical trials , 2002, Expert opinion on investigational drugs.
[29] J. Cameron,et al. Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. , 2003, Cancer research.
[30] S. Clark,et al. Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells , 2002, Oncogene.
[31] Jonathan A. Cooper,et al. Reelin-induced tryosine phosphorylation of Disabled 1 during neuronal positioning , 1999 .
[32] D. Grayson,et al. Histone deacetylase inhibitors decrease reelin promoter methylation in vitro , 2005, Journal of neurochemistry.
[33] J. Herman,et al. GATA-4 and GATA-5 Transcription Factor Genes and Potential Downstream Antitumor Target Genes Are Epigenetically Silenced in Colorectal and Gastric Cancer , 2003, Molecular and Cellular Biology.
[34] R. Blaheta,et al. Evolving anticancer drug valproic acid: Insights into the mechanism and clinical studies , 2005, Medicinal research reviews (Print).
[35] T. Curran,et al. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler , 1995, Nature.
[36] A. Guidotti,et al. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] A. Goffinet,et al. Reelin and brain development , 2003, Nature Reviews Neuroscience.
[38] Peter A. Jones,et al. The fundamental role of epigenetic events in cancer , 2002, Nature Reviews Genetics.
[39] Matty P. Weijenberg,et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer , 2002, Nature Genetics.
[40] S. Fatemi,et al. Reelin glycoprotein: structure, biology and roles in health and disease , 2005, Molecular Psychiatry.
[41] Y. Miyagi,et al. Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma , 2005, Oncogene.
[42] Ying Chen,et al. On the epigenetic regulation of the human reelin promoter , 2002, Nucleic Acids Res..
[43] R. Hruban,et al. Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma. , 2001, Cancer research.
[44] Peter A. Jones,et al. Epigenetics in human disease and prospects for epigenetic therapy , 2004, Nature.
[45] R. Hruban,et al. Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays , 2004, Oncogene.
[46] Wei Dong Chen,et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer , 2004, Nature Genetics.
[47] Jonathan A. Cooper,et al. Neuronal position in the developing brain is regulated by mouse disabled-1 , 1997, Nature.
[48] L. Schwartz,et al. Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[49] J. Herman,et al. Gene silencing in cancer in association with promoter hypermethylation. , 2003, The New England journal of medicine.
[50] M. Sheng,et al. Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2 , 2000, Nature.