One-pot Syntheses of 5-Oxo-1,4,5,6,7,8-hexahydroquinolinesand Pyrimido[4,5-b]quinolines using MicrowaveIrradiation and Ultrasound
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A rapid and efficient method for the synthesis of
alkyl
4-aryl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxoquinoline-3-car
boxylates by the condensation of
5,5-dimethylcyclohexane-1,3-dione and aromatic aldehydes with
methyl 3-aminocrotonate or ethyl acetoacetate in the presence of
ammonium acetate and of pyrimido[4,5-b]quinolines by the
condensation of N-methylaniline with an aromatic
aldehyde and 1,3-diaryl-2-thiobarbituric acid using microwave-
and ultrasound-induced methods is reported.
[1] C. Marchand,et al. Synthese organique sous champ microondes : premier exemple d'activation specifique en phase homogene , 1991 .
[2] T. Takenaka,et al. Synthesis of new water-soluble dihydropyridine vasodilators. , 1979, Chemical & pharmaceutical bulletin.