Ontology Based Metadata Management in Medical Domains

139 In medical research, one of major challenges is to archive, access, and analyse various heterogeneous databases containing patient information gathered from a large volume of data over a long period of time. The main objective of this paper is (1) to examine how the use of metadata and ontologies can support the management and integration of clinical research databases and (2) to present our ontology-based metadata management system developed for the Cardiovascular Research Department at MAHI. Using the concept of web services, our system is globally accessible. The system is currently deployed on the existing medical information system at Mid America Heart Institute (MAHI) and used for clinical research.

[1]  Dieter Fensel,et al.  Ontologies: A silver bullet for knowledge management and electronic commerce , 2002 .

[2]  Vipul Kashyap,et al.  Information Brokering Across Heterogeneous Digital Data , 2000, Advances in Database Systems.

[3]  A. Bouguettaya,et al.  Healthcare data warehousing and quality assurance , 2001 .

[4]  Anca Vaduva,et al.  Metadata Management for Data Warehousing: An Overview , 2001, Int. J. Cooperative Inf. Syst..

[5]  Jerry Fowler,et al.  The Healthcare Administrator's Associate: an experiment in distributed healthcare information systems , 1997, AMIA.

[6]  Diego Calvanese,et al.  Description Logic Framework for Information Integration , 1998, KR.

[7]  Catriel Beeri,et al.  Ontology-Based Integration of XML Web Resources , 2002, SEMWEB.

[8]  Paul O'Brien,et al.  Issues in Ontology-based Information Integration , 2001, OIS@IJCAI.

[9]  Antonio Badia,et al.  Ontologies , 2001, Springer Berlin Heidelberg.

[10]  D. Lindberg,et al.  The Unified Medical Language System , 1993, Methods of Information in Medicine.

[11]  Bob J. Wielinga,et al.  Using explicit ontologies in KBS development , 1997, Int. J. Hum. Comput. Stud..

[12]  Stéphane Bressan,et al.  Integration of Disparate Information Sources: A Short Survey , 1999 .

[13]  Tova Milo,et al.  Views in a large-scale XML repository , 2002, The VLDB Journal.

[14]  Dennis Gannon,et al.  A component based services architecture for building distributed applications , 2000, Proceedings the Ninth International Symposium on High-Performance Distributed Computing.

[15]  Jules J. Berman.  A tool for sharing annotated research data: the "Category 0" UMLS (Unified Medical Language System) vocabularies , 2003, BMC Medical Informatics Decis. Mak..

[16]  Alan R. Hevner,et al.  Healthcare Data Warehousing and Quality Assurance , 2001, Computer.

[17]  Thomas R. Gruber,et al.  Toward principles for the design of ontologies used for knowledge sharing? , 1995, Int. J. Hum. Comput. Stud..

[18]  Torben Bach Pedersen,et al.  Research issues in clinical data warehousing , 1998, Proceedings. Tenth International Conference on Scientific and Statistical Database Management (Cat. No.98TB100243).

[19]  Jane Grimson,et al.  Sharing Health-Care Records over the Internet , 2001, IEEE Internet Comput..

[20]  Diego Calvanese,et al.  A Framework for Ontology Integration , 2001, The Emerging Semantic Web.

[21]  Terence Critchlow,et al.  Meta-data based mediator generation , 1998, Proceedings. 3rd IFCIS International Conference on Cooperative Information Systems (Cat. No.98EX122).