Compartmental analysis--II: ACT, a program for compartmental models of the generalized Michaelis-Menten type.

Abstract An adequate approach of biological systems requires most of the time the use of non-linear models. A general theoretical model for compartmental analysis, essentially based on the Michaelis-Menten laws, is presented here, as well as the algorithmical developments solving the classical problems of simulation and of fitting, and the problems of predetermination and of latency time. Besides the theoretical aspect, a new FORTRAN program, ACT, allowing to handle all the mentioned problems, is made available.