Structure of the C2 domain of human factor VIII at 1.5 Å resolution

[1]  Y. Nieh,et al.  A two-dimensional histogram-matching method for protein phase refinement and extension. , 1999, Acta crystallographica. Section D, Biological crystallography.

[2]  M. Shima,et al.  Mapping of the minimal domain encoding a conformational epitope by lambda phage surface display: factor VIII inhibitor antibodies from haemophilia A patients. , 1999, Journal of immunological methods.

[3]  E. Getzoff,et al.  Homology models of the C domains of blood coagulation factors V and VIII: a proposed membrane binding mode for FV and FVIII C2 domains. , 1998, Blood cells, molecules & diseases.

[4]  J. Healey,et al.  Residues Glu2181-Val2243 contain a major determinant of the inhibitory epitope in the C2 domain of human factor VIII. , 1998, Blood.

[5]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[6]  M F Hoylaerts,et al.  Mechanism and kinetics of factor VIII inactivation: study with an IgG4 monoclonal antibody derived from a hemophilia A patient with inhibitor. , 1998, Blood.

[7]  Philipp Bucher,et al.  The discoidin domain family revisited: New members from prokaryotes and a homology‐based fold prediction , 1998, Protein science : a publication of the Protein Society.

[8]  J. Baleja,et al.  Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles. , 1998, The Biochemical journal.

[9]  E. Saenko,et al.  A Mechanism for Inhibition of Factor VIII Binding to Phospholipid by von Willebrand Factor (*) , 1995, The Journal of Biological Chemistry.

[10]  J. Baleja,et al.  Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy. , 1995, Biochemistry.

[11]  Collaborative Computational,et al.  The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.

[12]  L. Hoyer,et al.  Factor VIII inhibitors: structure and function in autoantibody and hemophilia A patients. , 1994, Seminars in hematology.

[13]  J. Thornton,et al.  PROCHECK: a program to check the stereochemical quality of protein structures , 1993 .

[14]  M. Shima,et al.  A Factor VIII Neutralizing Monoclonal Antibody and a Human Inhibitor Alloantibody Recognizing Epitopes in the C2 Domain Inhibit Factor VIII Binding to von Willebrand Factor and to Phosphatidylserine , 1993, Thrombosis and Haemostasis.

[15]  P. Lollar,et al.  Binding of factor VIIIa and factor VIII to factor IXa on phospholipid vesicles. , 1992, The Journal of biological chemistry.

[16]  P. Lollar,et al.  Intrinsic pathway activation of factor X and its activation peptide-deficient derivative, factor Xdes-143-191. , 1992, The Journal of biological chemistry.

[17]  J. Zou,et al.  Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.

[18]  P. Fay,et al.  von Willebrand factor mediates protection of factor VIII from activated protein C-catalyzed inactivation. , 1991, The Journal of biological chemistry.

[19]  Kenneth G. Mann,et al.  Surface-dependent reactions of the vitamin K-dependent enzyme complexes , 1990 .

[20]  R. Houghten,et al.  Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine. , 1990, Blood.

[21]  W. Kane,et al.  Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders. , 1988, Blood.

[22]  H. Hemker,et al.  The role of phospholipid and factor VIIIa in the activation of bovine factor X. , 1981, The Journal of biological chemistry.

[23]  P M Cullis,et al.  Affinities of amino acid side chains for solvent water. , 1981, Biochemistry.

[24]  Z. Otwinowski,et al.  [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.

[25]  Axel T. Brunger,et al.  Assessment of Phase Accuracy by Cross Validation: the Free R Value. Methods and Applications , 1993 .

[26]  R. Kaufman.  Biological regulation of factor VIII activity. , 1992, Annual Review of Medicine.

[27]  K. Mann,et al.  Assembly of the prothrombinase complex. , 1982, Biophysical journal.

[28]  M. Uschold,et al.  Methods and applications , 1953 .