Transgenic Mice Expressing Green Fluorescent Protein under the Control of the Melanocortin-4 Receptor Promoter
暂无分享,去创建一个
A. G. Roseberry | J. Friedman | J. Elmquist | Charlotte E. Lee | Hongyan Liu | T. Kishi | Joel K Elmquist | Charlotte E Lee | Hongyan Liu | Toshiro Kishi | Aaron G Roseberry | Xiaoli Cai | Jason M Montez | Jeffrey M Friedman | Xiaoli Cai | J. Montez | Toshiro Kishi
[1] G. Barsh,et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. , 1997, Science.
[2] H. Grill,et al. The Neuroanatomical Axis for Control of Energy Balance , 2002, Frontiers in Neuroendocrinology.
[3] J. Shutter,et al. Overexpression of Agrt leads to obesity in transgenic mice , 1997, Nature Genetics.
[4] T. Hökfelt,et al. Hypocretin/Orexin‐ and melanin‐concentrating hormone‐expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene‐related protein systems , 1998, The Journal of comparative neurology.
[5] M. Mortrud,et al. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[6] C. Saper,et al. From Lesions to Leptin Hypothalamic Control of Food Intake and Body Weight , 1999, Neuron.
[7] B. Pollock,et al. Leptin increases uncoupling protein expression and energy expenditure. , 1997, The American journal of physiology.
[8] C. Saper,et al. Differential expression of orexin receptors 1 and 2 in the rat brain , 2001, The Journal of comparative neurology.
[9] T. Hökfelt,et al. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[10] C. Saper,et al. The Need to Feed Homeostatic and Hedonic Control of Eating , 2002, Neuron.
[11] Michael W. Schwartz,et al. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons , 1998, Nature Neuroscience.
[12] J. B. Thomas,et al. Tau-beta-galactosidase, an axon-targeted fusion protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[13] E. Brown,et al. A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[14] Clifford B Saper,et al. Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area , 1999, Neuron.
[15] R. Cone,et al. Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice , 1997, Cell.
[16] G. Wolff,et al. Pancreatic Islet Cells in Preobese Yellow Avy/- Mice: Relation to Adult Hyperinsulinemia and Obesity , 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[17] P. Morgan,et al. Coexpression of Leptin Receptor and Preproneuropeptide Y mRNA in Arcuate Nucleus of Mouse Hypothalamus , 1996, Journal of neuroendocrinology.
[18] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1994, Nature.
[19] S. Gammeltoft,et al. A role for melanin-concentrating hormone in the central regulation of feeding behaviour , 1996, Nature.
[20] R. Seeley,et al. Melanocortin receptors in leptin effects , 1997, Nature.
[21] L. Swanson,et al. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radi , 1989 .
[22] M. Herkenham,et al. Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[23] J. Elmquist. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin , 2001, Physiology & Behavior.
[24] K. Clément,et al. A frameshift mutation in human MC4R is associated with a dominant form of obesity , 1998, Nature Genetics.
[25] J. Herman,et al. Ventral subicular interaction with the hypothalamic paraventricular nucleus: Evidence for a relay in the bed nucleus of the stria terminalis , 1993, The Journal of comparative neurology.
[26] B. Lowell,et al. Mice lacking melanin-concentrating hormone are hypophagic and lean , 1998, Nature.
[27] N. Heintz,et al. Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome , 1997, Nature Biotechnology.
[28] M. Erlander,et al. Two genes encode distinct glutamate decarboxylases , 1991, Neuron.
[29] B. Roland,et al. Local origins of some GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat , 1993, The Journal of comparative neurology.
[30] W. Rand,et al. Arcuate Nucleus Ablation Prevents Fasting-Induced Suppression of ProTRH mRNA in the Hypothalamic Paraventricular Nucleus , 1998, Neuroendocrinology.
[31] R. Steiner,et al. Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus. , 1997, Endocrinology.
[32] J. Priestley,et al. A combined in situ hybridization and immunofluorescence procedure allowing visualisation of peptide mRNA and serotonin in single sections , 1993, Journal of Neuroscience Methods.
[33] R. Cone,et al. The melanocortin receptors: Lessons from knockout models , 2002, Neuropeptides.
[34] S. Carr,et al. Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior , 1998, Cell.
[35] K. Nakao,et al. Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system , 1998, Neuroscience Letters.
[36] A. Levine,et al. Neural site of leptin influence on neuropeptide Y signaling pathways altering feeding and uncoupling protein. , 1998, American journal of physiology. Regulatory, integrative and comparative physiology.
[37] Akil,et al. The Effect of Stressor Controllability on Stress‐Induced Neuropeptide mRNA Expression within the Paraventricular Nucleus of the Hypothalamus , 1999, Journal of neuroendocrinology.
[38] G. Barsh,et al. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area , 1998, The Journal of comparative neurology.
[39] C. Saper,et al. Neurochemical organization of the hypothalamic projection to the spinal cord in the rat , 1988, The Journal of comparative neurology.
[40] J. Flier,et al. Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. , 2001, The Journal of clinical investigation.
[41] J. Halaas,et al. Leptin and the regulation of body weight in mammals , 1998, Nature.
[42] G. Paxinos. The Rat nervous system , 1985 .
[43] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1995, Nature.
[44] R. Steiner,et al. Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. , 1997, Endocrinology.
[45] P. Sawchenko,et al. Toward a new neurobiology of energy balance, appetite, and obesity: The anatomists weigh in , 1998, The Journal of comparative neurology.
[46] L. Yaswen,et al. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin , 1999, Nature Medicine.
[47] D. Drucker,et al. Glucagon-Like Peptide-1-Responsive Catecholamine Neurons in the Area Postrema Link Peripheral Glucagon-Like Peptide-1 with Central Autonomic Control Sites , 2003, The Journal of Neuroscience.
[48] W. Rand,et al. a-Melanocyte-Stimulating Hormone Is Contained in Nerve Terminals Innervating Thyrotropin-Releasing Hormone-Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Prevents Fasting-Induced Suppression of Prothyrotropin-Releasing Hormone Gene Expression , 2000 .
[49] M. Mortrud,et al. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. , 1994, Molecular endocrinology.
[50] C. Saper,et al. Distributions of leptin receptor mRNA isoforms in the rat brain , 1998, The Journal of comparative neurology.
[51] J. Tasker,et al. Physiological Mapping of Local Inhibitory Inputs to the Hypothalamic Paraventricular Nucleus , 1996, The Journal of Neuroscience.
[52] A. Grüters,et al. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans , 1998, Nature Genetics.
[53] V. Rivera,et al. Transcriptional squelching re-examined , 1997, Nature.
[54] C. Priest,et al. Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin , 1998, Diabetes.
[55] J. Vaughan,et al. The melanin‐concentrating hormone system of the rat brain: An immuno‐ and hybridization histochemical characterization , 1992, The Journal of comparative neurology.
[56] C. Saper. The central autonomic system , 1995 .
[57] S. Woods,et al. Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus , 1997, Diabetes.
[58] S. O’Rahilly,et al. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. , 2000, The Journal of clinical investigation.
[59] S. Carr,et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. , 1998, Cell.
[60] R. Cone,et al. Integration of NPY, AGRP, and Melanocortin Signals in the Hypothalamic Paraventricular Nucleus Evidence of a Cellular Basis for the Adipostat , 1999, Neuron.
[61] C. Saper,et al. Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat , 2003, The Journal of comparative neurology.
[62] R. Cone,et al. Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat , 2001, Nature Neuroscience.
[63] P. Sawchenko,et al. Type 1 interleukin‐1 receptor in the rat brain: Distribution, regulation, and relationship to sites of IL‐1–induced cellular activation , 1995, The Journal of comparative neurology.
[64] Victor J. Hruby,et al. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome , 1997, Nature.
[65] George Paxinos,et al. The Mouse Brain in Stereotaxic Coordinates , 2001 .
[66] B. Spiegelman,et al. Adipogenesis and Obesity: Rounding Out the Big Picture , 1996, Cell.
[67] T. Kishi,et al. Topographical organization of projections from the subiculum to the hypothalamus in the rat , 2000, The Journal of comparative neurology.
[68] T. Robinson,et al. A 6-Hydroxydopamine lesion of the mesostriatal dopamine system decreases the expression of corticotropin releasing hormone and neurotensin mRNAs in the amygdala and bed nucleus of the stria terminalis , 2002, Brain Research.
[69] C. Saper,et al. Activation of neurons projecting to the paraventricular hypothalamic nucleus by intravenous lipopolysaccharide , 1996, The Journal of comparative neurology.
[70] R. Cone,et al. Independent and additive effects of central POMC and leptin pathways on murine obesity. , 1997, Science.