The dysregulation of tRNAs and tRNA derivatives in cancer

[1]  R. Maraia.  Faculty of 1000 evaluation for A transfer-RNA-derived small RNA regulates ribosome biogenesis. , 2018 .

[2]  Yongmei Yin,et al.  Roles of tRNA-derived fragments in human cancers. , 2018, Cancer letters.

[3]  Sunghoon Kim,et al.  Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation , 2018, RNA biology.

[4]  N. Savage.  New tricks from old dogs join the fight against ageing , 2017, Nature.

[5]  Zhiming He,et al.  Role of Brf1 interaction with ERα, and significance of its overexpression, in human breast cancer , 2017, Molecular oncology.

[6]  Paolo Visca,et al.  tsRNA signatures in cancer , 2017, Proceedings of the National Academy of Sciences.

[7]  R. Martienssen,et al.  LTR-Retrotransposon Control by tRNA-Derived Small RNAs , 2017, Cell.

[8]  ping wang,et al.  tRF‐Leu‐CAG promotes cell proliferation and cell cycle in non‐small cell lung cancer , 2017, Chemical biology & drug design.

[9]  Megumi Shigematsu,et al.  5′-Terminal nucleotide variations in human cytoplasmic tRNAHisGUG and its 5′-halves , 2017, RNA.

[10]  J. Zhao,et al.  Mutational Analysis of Mitochondrial tRNA Genes in Patients with Lung Cancer , 2016, Balkan journal of medical genetics : BJMG.

[11]  Sebastian A. Leidel,et al.  Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer , 2016, The Journal of experimental medicine.

[12]  Y. Loh,et al.  Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression. , 2016, The Journal of clinical investigation.

[13]  O. Kovalchuk,et al.  Genome-wide profiling of transfer RNAs and their role as novel prognostic markers for breast cancer , 2016, Scientific Reports.

[14]  Yu-hua Qin,et al.  The role of mitochondrial tRNA variants in female breast cancer , 2016, Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis.

[15]  Matthew P. Neilson,et al.  The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma , 2016, Biology Open.

[16]  T. Pan,et al.  Interaction of tRNA with MEK2 in pancreatic cancer cells , 2016, Scientific Reports.

[17]  Henrik Molina,et al.  Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression , 2016, Cell.

[18]  Giovanni Nigita,et al.  Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer , 2016, Proceedings of the National Academy of Sciences.

[19]  J. Norman,et al.  The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis , 2016, Current Biology.

[20]  Gyorgy Hutvagner,et al.  tRNA-Derived Fragments (tRFs): Emerging New Roles for an Ancient RNA in the Regulation of Gene Expression , 2015, Life.

[21]  M. Hatzoglou,et al.  The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health* , 2015, The Journal of Biological Chemistry.

[22]  D. Wallace.  Mitochondrial DNA Variation in Human Radiation and Disease , 2015, Cell.

[23]  Yongkui Zhang,et al.  The role of mitochondrial tRNA mutations in lung cancer. , 2015, International journal of clinical and experimental medicine.

[24]  S. Grewal.  Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth. , 2015, Biochimica et biophysica acta.

[25]  Phillipe Loher,et al.  Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers , 2015, Proceedings of the National Academy of Sciences.

[26]  Lisa Fish,et al.  Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement , 2015, Cell.

[27]  Lianbo Yu,et al.  Breast Cancer–Specific miR Signature Unique to Extracellular Vesicles Includes “microRNA-like” tRNA Fragments , 2015, Molecular Cancer Research.

[28]  J. Byrd,et al.  TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia , 2015, Proceedings of the National Academy of Sciences.

[29]  Z. Ignatova,et al.  Emerging roles of tRNA in adaptive translation, signalling dynamics and disease , 2014, Nature Reviews Genetics.

[30]  Michaela Frye,et al.  Role of RNA methyltransferases in tissue renewal and pathology , 2014, Current opinion in cell biology.

[31]  Pavel Ivanov,et al.  tRNA fragments in human health and disease , 2014, FEBS letters.

[32]  Suresh B. Mudunuri,et al.  Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets , 2014, BMC Biology.

[33]  Sebastian M. Waszak,et al.  A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation , 2014, Cell.

[34]  Eduard Batlle,et al.  Role of tRNA modifications in human diseases. , 2014, Trends in molecular medicine.

[35]  J. Steitz,et al.  The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones , 2014, Cell.

[36]  David I. K. Martin,et al.  Deep Sequencing of Serum Small RNAs Identifies Patterns of 5′ tRNA Half and YRNA Fragment Expression Associated with Breast Cancer , 2014, Biomarkers in cancer.

[37]  C. Print,et al.  Links between the Oncoprotein YB-1 and Small Non-Coding RNAs in Breast Cancer , 2013, PloS one.

[38]  T. Pan,et al.  Reversible and Rapid Transfer-RNA Deactivation as a Mechanism of Translational Repression in Stress , 2013, PLoS genetics.

[39]  G. Hutvagner,et al.  Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells , 2013, RNA biology.

[40]  T. Pan,et al.  Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. , 2013, RNA.

[41]  Peng Yao,et al.  Aminoacyl-tRNA synthetases in medicine and disease , 2013, EMBO molecular medicine.

[42]  Andrea Califano,et al.  tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma , 2013, Proceedings of the National Academy of Sciences.

[43]  Eva Maria Novoa,et al.  Speeding with control: codon usage, tRNAs, and ribosomes. , 2012, Trends in genetics : TIG.

[44]  T. Begley,et al.  Transfer RNA methytransferases and their corresponding modifications in budding yeast and humans: activities, predications, and potential roles in human health. , 2012, DNA and cell biology.

[45]  B. Ślaska,et al.  Polymorphisms in genes encoding mt-tRNA in female breast cancer in Poland , 2012, Mitochondrial DNA.

[46]  Michal Linial,et al.  Conservation of the relative tRNA composition in healthy and cancerous tissues. , 2012, RNA.

[47]  T. Pan,et al.  A Role for tRNA Modifications in Genome Structure and Codon Usage , 2012, Cell.

[48]  E. Marcotte,et al.  Insights into the regulation of protein abundance from proteomic and transcriptomic analyses , 2012, Nature Reviews Genetics.

[49]  Patrick Cramer,et al.  Review Conservation between the Rna Polymerase I, Ii, and Iii Transcription Initiation Machineries , 2022 .

[50]  Takeo Suzuki,et al.  Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases. , 2011, Annual review of genetics.

[51]  Steven P Gygi,et al.  Angiogenin-induced tRNA fragments inhibit translation initiation. , 2011, Molecular cell.

[52]  M. Selbach,et al.  Global quantification of mammalian gene expression control , 2011, Nature.

[53]  Wolfgang Wintermeyer,et al.  The ribosome as a molecular machine: the mechanism of tRNA-mRNA movement in translocation. , 2011, Biochemical Society transactions.

[54]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[55]  Robert A. Weinberg,et al.  Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts , 2010, Proceedings of the National Academy of Sciences.

[56]  A. Hopper,et al.  tRNA biology charges to the front. , 2010, Genes & development.

[57]  D. Haussecker,et al.  Human tRNA-derived small RNAs in the global regulation of RNA silencing. , 2010, RNA.

[58]  J. Yong,et al.  tRNA binds to cytochrome c and inhibits caspase activation. , 2010, Molecular cell.

[59]  G. Barton,et al.  Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. , 2009, RNA.

[60]  A. Malhotra,et al.  A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). , 2009, Genes & development.

[61]  T. Pan,et al.  tRNA over-expression in breast cancer and functional consequences , 2009, Nucleic acids research.

[62]  T. Pan,et al.  High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma. , 2009, Biochemical and biophysical research communications.

[63]  R. Parker,et al.  Stressing Out over tRNA Cleavage , 2009, Cell.

[64]  Yidong Bai,et al.  Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis , 2009, Cell Research.

[65]  Masayuki Nashimoto,et al.  Modulation of Gene Expression by Human Cytosolic tRNase ZL through 5′-Half-tRNA , 2009, PloS one.

[66]  S. Yamasaki,et al.  Angiogenin cleaves tRNA and promotes stress-induced translational repression , 2009, The Journal of cell biology.

[67]  P. Zamore,et al.  Small silencing RNAs: an expanding universe , 2009, Nature Reviews Genetics.

[68]  Richard Giegé,et al.  Toward a more complete view of tRNA biology , 2008, Nature Structural &Molecular Biology.

[69]  Pamela J Green,et al.  tRNA cleavage is a conserved response to oxidative stress in eukaryotes. , 2008, RNA.

[70]  Deborah L. Johnson,et al.  Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation*♦ , 2008, Journal of Biological Chemistry.

[71]  A. Sandelin,et al.  Hidden layers of human small RNAs , 2008, BMC Genomics.

[72]  J. Rollins,et al.  Human Maf1 negatively regulates RNA Polymerase III transcription via the TFIIB family members Brf1 and Brf2 , 2007, International journal of biological sciences.

[73]  Paul F Agris,et al.  tRNA's wobble decoding of the genome: 40 years of modification. , 2007, Journal of molecular biology.

[74]  F. Watt,et al.  The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregulated in Tumors , 2006, Current Biology.

[75]  A. Tinker,et al.  The challenges of gene expression microarrays for the study of human cancer. , 2006, Cancer cell.

[76]  Laurent Lestrade,et al.  snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs , 2005, Nucleic Acids Res..

[77]  D. Spandidos,et al.  Deregulation of RNA polymerase III transcription in cervical epithelium in response to high-risk human papillomavirus , 2005, Oncogene.

[78]  S. Govindarajan,et al.  Codon bias and heterologous protein expression. , 2004, Trends in biotechnology.

[79]  C. Florentz,et al.  Human mitochondrial tRNAs in health and disease , 2003, Cellular and Molecular Life Sciences CMLS.

[80]  J. Milner,et al.  p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB , 2003, The EMBO journal.

[81]  R. Eisenman,et al.  Direct activation of RNA polymerase III transcription by c-Myc , 2003, Nature.

[82]  A. Hopper,et al.  tRNA transfers to the limelight. , 2003, Genes & development.

[83]  G. Amuthan,et al.  Mitochondria‐to‐nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion , 2001, The EMBO journal.

[84]  W. Keller,et al.  An adenosine deaminase that generates inosine at the wobble position of tRNAs. , 1999, Science.

[85]  J. Steitz,et al.  Modification of U6 spliceosomal RNA is guided by other small RNAs. , 1998, Molecular cell.

[86]  A. Berk,et al.  Polymerase (Pol) III TATA Box-Binding Protein (TBP)-Associated Factor Brf Binds to a Surface on TBP Also Required for Activated Pol II Transcription , 1998, Molecular and Cellular Biology.

[87]  D. Johnson,et al.  Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway , 1997, Molecular and cellular biology.

[88]  S. Jackson,et al.  Repression of RNA polymerase III transcription by the retinoblastoma protein , 1996, Nature.

[89]  R. Cardiff,et al.  Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease , 1992, Molecular and cellular biology.

[90]  R. Levitz,et al.  The optional E. coli prr locus encodes a latent form of phage T4‐induced anticodon nuclease. , 1990, The EMBO journal.

[91]  K. Kuo,et al.  tRNA breakdown products as markers for cancer , 1979, Cancer.

[92]  S. Belman,et al.  High turnover rate of transfer RNA in tumor tissue. , 1977, Cancer research.

[93]  A. Jemal,et al.  Cancer statistics, 2017 , 2017, CA: a cancer journal for clinicians.

[94]  Tharun,et al.  Elp 3 links tRNA modification to IRES-dependent translation of LEF 1 to sustain metastasis in breast cancer , 2016 .

[95]  Charles M. Perou,et al.  Practical implications of gene-expression-based assays for breast oncologists , 2012, Nature Reviews Clinical Oncology.

[96]  P. Fumoleau,et al.  The Paradox of Triple Negative Breast Cancer: Novel Approaches to Treatment , 2012, The breast journal.

[97]  M. Nashimoto,et al.  A novel 4-base-recognizing RNA cutter that can remove the single 3' terminal nucleotides from RNA molecules. , 2004, Nucleic acids research.

[98]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.

[99]  C. Florentz,et al.  Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern. , 1998, Nucleic acids research.

[100]  N. Dubrawsky.  Cancer statistics , 1989, CA: a cancer journal for clinicians.