A biosynthetic pathway for a prominent class of microbiota-derived bile acids

[1]  Philipp Stiefel,et al.  Critical aspects of using bacterial cell viability assays with the fluorophores SYTO9 and propidium iodide , 2015, BMC Microbiology.

[2]  M. Fischbach,et al.  The Prevalence of Species and Strains in the Human Microbiome: A Resource for Experimental Efforts , 2014, PloS one.

[3]  S. Fukiya,et al.  Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon[S] , 2013, Journal of Lipid Research.

[4]  Masahira Hattori,et al.  Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome , 2013, Nature.

[5]  P. Turnbaugh,et al.  Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome , 2013, Cell.

[6]  Peer Bork,et al.  Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy , 2011, Nucleic Acids Res..

[7]  R. Schmid,et al.  Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens , 2011, Applied Microbiology and Biotechnology.

[8]  P. Hylemon,et al.  Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. , 2010, Anaerobe.

[9]  O. Gascuel,et al.  New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. , 2010, Systematic biology.

[10]  Johan Auwerx,et al.  Targeting bile-acid signalling for metabolic diseases , 2008, Nature Reviews Drug Discovery.

[11]  V..  New Genus , Coprococcus , Twelve New Species , and Emended Descriptions of Four Previously Described Species of Bacteria from Human Feces , 2008 .

[12]  S. Dridi,et al.  Chenodeoxycholic acid suppresses the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317 Published, JLR Papers in Press, September 6, 2007. , 2007, Journal of Lipid Research.

[13]  J. Steinbach,et al.  Human cecal bile acids: concentration and spectrum. , 2007, American journal of physiology. Gastrointestinal and liver physiology.

[14]  Dae-Joong Kang,et al.  Bile salt biotransformations by human intestinal bacteria Published, JLR Papers in Press, November 18, 2005. , 2006, Journal of Lipid Research.

[15]  C. Hill,et al.  The interaction between bacteria and bile. , 2005, FEMS microbiology reviews.

[16]  A. Hofmann,et al.  Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis part II , 1982, Digestive Diseases and Sciences.

[17]  A. Hofmann,et al.  Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis , 2005, Digestive Diseases and Sciences.

[18]  Robert C. Edgar,et al.  MUSCLE: multiple sequence alignment with high accuracy and high throughput. , 2004, Nucleic acids research.

[19]  Jesse D. Martinez,et al.  Ursodeoxycholic acid (UDCA) can inhibit deoxycholic acid (DCA)-induced apoptosis via modulation of EGFR/Raf-1/ERK signaling in human colon cancer cells. , 2004, The Journal of nutrition.

[20]  P. Hylemon,et al.  Expression in Escherichia coli and characterization of a bile acid-inducible 3α-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 , 1995, Current Microbiology.

[21]  S. McKnight,et al.  Cloning and Characterization of the NAD-Dependent 7α-Hydroxysteroid Dehydrogenase from Bacteroides fragilis , 2003, Current Microbiology.

[22]  G. Kociubinski,et al.  Effect of bile on the lipid composition and surface properties of bifidobacteria , 2002, Journal of applied microbiology.

[23]  M. Haussler,et al.  Vitamin D Receptor As an Intestinal Bile Acid Sensor , 2002, Science.

[24]  Keisuke Matsuoka,et al.  Micelle formation of sodium deoxycholate and sodium ursodeoxycholate (part 1). , 2002, Biochimica et biophysica acta.

[25]  P. Hylemon,et al.  Identification and Characterization of a Bile Acid 7α-Dehydroxylation Operon in Clostridium sp. Strain TO-931, a Highly Active 7α-Dehydroxylating Strain Isolated from Human Feces , 2000, Applied and Environmental Microbiology.

[26]  L. Hudson,et al.  Characterization and regulation of the NADP-linked 7 alpha-hydroxysteroid dehydrogenase gene from Clostridium sordellii , 1994, Journal of bacteriology.

[27]  D. Noh,et al.  Influence of bile on cellular integrity and beta-galactosidase activity of Lactobacillus acidophilus. , 1993, Journal of dairy science.

[28]  A. Hofmann,et al.  A proposed nomenclature for bile acids. , 1992, Journal of lipid research.

[29]  S. F. Baron,et al.  Cloning, sequencing, and expression of the gene coding for bile acid 7 alpha-hydroxysteroid dehydrogenase from Eubacterium sp. strain VPI 12708 , 1991, Journal of bacteriology.

[30]  R. Edenharder,et al.  Characterization of NAD-dependent 3α- and 3β-hydroxysteroid dehydrogenase and of NADP-dependent 7β-hydroxysteroid dehydrogenase from Peptostreptococcus productus , 1989 .

[31]  R. Edenharder,et al.  NADP-dependent 3β-, 7α- and 7β-hydroxysteroid dehydrogenase activities from a lecithinase-lipase-negative Clostridium species 25.11.c , 1989 .

[32]  D. Kritchevsky,et al.  The Bile Acids: Chemistry, Physiology, and Metabolism , 1988, Springer US.

[33]  W. R. Bruce,et al.  Cellular toxicity of fecal water depends on diet. , 1987, The American journal of clinical nutrition.

[34]  K. Kobashi,et al.  3 beta-Hydroxysteroid dehydrogenase of Ruminococcus sp. from human intestinal bacteria. , 1986, Journal of biochemistry.

[35]  J. Sjövall,et al.  Mass spectrometry of bile acids. , 1985, Methods in enzymology.

[36]  K. Setchell,et al.  General methods for the analysis of metabolic profiles of bile acids and related compounds in feces. , 1983, Journal of lipid research.

[37]  E. Mosbach,et al.  Degradation of steroids in the human gut. , 1983, Journal of lipid research.

[38]  T. P. Forrest,et al.  Metabolism of primary bile acids by Clostridium perfringens. , 1983, Journal of steroid biochemistry.

[39]  S. Hirano,et al.  Transformation of bile acids by Eubacterium lentum , 1981, Applied and environmental microbiology.

[40]  H. Oda,et al.  Transformation of bile acids by Clostridium perfringens , 1981, Applied and environmental microbiology.

[41]  L. Holdeman,et al.  Bile Salt 3α- and 12α-Hydroxysteroid Dehydrogenases from Eubacterium lentum and Related Organisms , 1979 .

[42]  I. Macdonald,et al.  Nad-dependent 3α- and 12α-hydroxysteroid dehydrogenase activities from eubacterwm lentum atcc no. 25559 , 1977 .

[43]  I. Macdonald,et al.  3α-, 7α- And 12α-hydroxysteroid dehydrogenase activities from Clostridium perfringens , 1976 .

[44]  E. Wynder,et al.  Promoting effect of sodium deoxycholate on colon adenocarcinomas in germfree rats. , 1976, Journal of the National Cancer Institute.

[45]  E. Wynder,et al.  Effects of high risk and low risk diets for colon carcinogenesis on fecal microflora and steroids in man. , 1975, The Journal of nutrition.

[46]  E. Wynder,et al.  Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats. , 1974, Journal of the National Cancer Institute.

[47]  W. Moore,et al.  New Genus, Coprococcus, Twelve New Species, and Emended Descriptions of Four Previously Described Species of Bacteria from Human Feces , 1974 .

[48]  S. Hayakawa.  Microbiological transformation of bile acids. , 1973, Advances in lipid research.