Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor.
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M. Oka | Masahiro Yoshida | T. Murase | Noriyasu Kato | M. Sakairi | S. Yamashita | Yoshika Yasuda | Aya Yoshikawa | Yuuji Hayashi | M. Makino | M. Takeda | Y. Mirensha | T. Kakigami | Y. Hayashi