Fine Needle Aspiration of Angiomatoid Malignant Fibrous Histiocytoma

BACKGROUND During recent years, reliable cytodiagnostic criteria have been proposed for a number of soft tissue lesions, both benign and malignant. However, cytomorphologic descriptions of angiomatoid malignant fibrous histiocytoma (AMFH) are lacking. We report the cytomorphologic features of this uncommon lesion. CASE A 10-year-old female presented with a swelling in the thigh that, on fine needle aspiration (FNA), was reported as a soft tissue tumor (vasoformative) of intermediate malignancy. Subsequent excision with histopathologic examination confirmed the diagnosis. CONCLUSION The differential diagnosis of AMFH based on FNA findings can be difficult and should be made in conjunction with clinical findings.