Hippocampal volume and antidepressant response in geriatric depression

Biological markers of treatment response may include structural brain changes seen on neuroimaging. While most imaging studies have focused on cerebrovascular disease, evidence is growing that the hippocampus may play a role in depression, particularly geriatric depression.

[1]  G. Burrows,et al.  Sustained Response to Open-Label Venlafaxine in Drug-Resistant Major Depression , 2001, Journal of clinical psychopharmacology.

[2]  H. Wagner,et al.  Severity of Subcortical Gray Matter Hyperintensity Predicts ECT Response in Geriatric Depression , 2001, The journal of ECT.

[3]  O. Forlenza,et al.  Antidepressant Efficacy and Safety of Low-Dose Sertraline and Standard-Dose Imipramine for the Treatment of Depression in Older Adults: Results From a Double-Blind, Randomized, Controlled Clinical Trial , 2001, International Psychogeriatrics.

[4]  D. Kupfer,et al.  Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression , 2000, Neuropsychopharmacology.

[5]  P. Jerabek,et al.  Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response , 2000, Biological Psychiatry.

[6]  James R MacFall,et al.  Hippocampal volume in geriatric depression , 2000, Biological Psychiatry.

[7]  S. Southwick,et al.  Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. , 2000, The American journal of psychiatry.

[8]  Deborah A Yurgelun-Todd,et al.  Hippocampal volume in primary unipolar major depression: a magnetic resonance imaging study , 2000, Biological Psychiatry.

[9]  E Mervaala,et al.  Quantitative MRI of the hippocampus and amygdala in severe depression , 2000, Psychological Medicine.

[10]  C. Mehringer,et al.  Clinical and neuroradiologic features associated with chronicity in late-life depression. , 1999, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[11]  Yvette I. Sheline,et al.  Depression Duration But Not Age Predicts Hippocampal Volume Loss in Medically Healthy Women with Recurrent Major Depression , 1999, The Journal of Neuroscience.

[12]  B. Tress,et al.  Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study , 1998, BMJ.

[13]  A. Burns,et al.  Is subcortical disease associated with a poor response to antidepressants? Neurological, neuropsychological and neuroradiological findings in late-life depression , 1998, Psychological Medicine.

[14]  A. Convit,et al.  Cortisol levels during human aging predict hippocampal atrophy and memory deficits , 1998, Nature Neuroscience.

[15]  R. Baldwin,et al.  Subcortical Hyperintensities in Late-Life Depression: Acute Response to Treatment and Neuropsychological Impairment , 1997, International Psychogeriatrics.

[16]  Henry Brodaty,et al.  Subcortical hyperintensities on magnetic resonance imaging in patients with severe depression—A longitudinal evaluation , 1997, Biological Psychiatry.

[17]  C. Montigny,et al.  The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments , 1997, Brain Research Reviews.

[18]  J. Csernansky,et al.  Hippocampal atrophy in recurrent major depression. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[19]  K. Ranga R. Krishnan,et al.  Relative accuracy and reproducibility of regional MRI brain volumes for point-counting methods , 1994, Psychiatry Research: Neuroimaging.

[20]  James C. Ehrhardt,et al.  Subcortical and temporal structures in affective disorder and schizophrenia: A magnetic resonance imaging study , 1992, Biological Psychiatry.

[21]  D. Blazer,et al.  Alternative models of the stress buffering hypothesis , 1989, American journal of community psychology.

[22]  B. McEwen,et al.  The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. , 1986, Endocrine reviews.

[23]  L. Robins,et al.  National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. , 1981, Archives of general psychiatry.

[24]  M. Åsberg,et al.  A New Depression Scale Designed to be Sensitive to Change , 1979, British Journal of Psychiatry.

[25]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[26]  L. Staib,et al.  Hippocampal volume reduction in major depression. , 2000, The American journal of psychiatry.

[27]  S. Yamawaki,et al.  The 3-year course and outcome of patients with major depression and silent cerebral infarction. , 1998, Journal of affective disorders.

[28]  B. Carroll,et al.  A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility. , 1981, Archives of general psychiatry.