Primary Osteosarcoma of the Breast: A Case Report

Introduction. Primary osteosarcoma of the breast is a rare soft-tissue form of osteosarcoma without involvement of the skeletal system. Due to the rarity of the disease, its clinical features and optimal treatment remain unclear. Case Presentation. This case report deals with a 62-year-old woman with pure osteosarcoma of the breast. Conclusions. The prognosis of primary osteosarcoma of the breast is poor. Recurrence is frequent, and it is often associated with haematogenous spread of the disease to the lung. Treatment follows the model of sarcomas affecting other locations and must be planned in a multidisciplinary fashion. Adjuvant chemotherapy should be considered for patients with tumors showing aggressive features.

[1]  M. Szajewski,et al.  Primary osteosarcoma of the breast: A case report , 2014, Oncology letters.

[2]  Chintamani,et al.  Osteogenic sarcoma of the breast arising in a cystosarcoma phyllodes: a case report and review of the literature , 2011, Journal of medical case reports.

[3]  K. Zaman,et al.  Breast sarcomas: current and future perspectives. , 2011, Breast.

[4]  C. Adebamowo,et al.  Primary osteogenic sarcoma of the breast , 2006, World journal of surgical oncology.

[5]  B. Asselain,et al.  Radiation‐induced sarcomas after radiotherapy for breast carcinoma , 2005, Cancer.

[6]  C. Reynolds,et al.  Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature , 2004, British Journal of Cancer.

[7]  H. Gutman,et al.  Role of radiotherapy in sarcoma of the breast--a retrospective review of the M.D. Anderson experience. , 1999, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[8]  F. Tavassoli,et al.  Osteosarcomatous differentiation in phyllodes tumors. , 1999, The American journal of surgical pathology.

[9]  S. Shrikhande,et al.  Primary osteogenic sarcoma of the breast. (A case report). , 1971, Indian journal of cancer.