Migration of mesenchymal stem cells towards glioblastoma cells depends on hepatocyte-growth factor and is enhanced by aminolaevulinic acid-mediated photodynamic treatment.

[1]  G. Finocchiaro,et al.  The MET oncogene is a functional marker of a glioblastoma stem cell subtype. , 2012, Cancer research.

[2]  J. Selbig,et al.  Mesenchymal stem cells and glioma cells form a structural as well as a functional syncytium in vitro , 2012, Experimental Neurology.

[3]  I. Germano,et al.  Stem cells as therapeutic vehicles for the treatment of high-grade gliomas. , 2012, Neuro-oncology.

[4]  F. Marincola,et al.  Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma , 2011, Proceedings of the National Academy of Sciences.

[5]  H. Steiger,et al.  Heat-shock protein 70-dependent dendritic cell activation by 5-aminolevulinic acid-mediated photodynamic treatment of human glioblastoma spheroids in vitro , 2011, British Journal of Cancer.

[6]  H. Steiger,et al.  Modulation of migratory activity and invasiveness of human glioma spheroids following 5-aminolevulinic acid-based photodynamic treatment. Laboratory investigation. , 2011, Journal of neurosurgery.

[7]  P. Wen,et al.  A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma. , 2011, Neuro-oncology.

[8]  J. Chang,et al.  Irradiation Enhances the Tumor Tropism and Therapeutic Potential of Tumor Necrosis Factor‐Related Apoptosis‐Inducing Ligand‐Secreting Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells in Glioma Therapy , 2010, Stem cells.

[9]  Bin Yu,et al.  Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro. , 2010, Oncology reports.

[10]  C. Gondi,et al.  Human umbilical cord blood stem cells show PDGF-D-dependent glioma cell tropism in vitro and in vivo. , 2010, Neuro-Oncology.

[11]  L. Zitvogel,et al.  Decoding Cell Death Signals in Inflammation and Immunity , 2010, Cell.

[12]  D. Feng,et al.  Stabilization of hepatocyte growth factor mRNA by hypoxia-inducible factor 1 , 2009, Molecular Biology Reports.

[13]  Hui Wang,et al.  CXCR4 and SDF-1 Production Are Stimulated by Hepatocyte Growth Factor and Promote Glioma Cell Invasion , 2009, Oncology Research and Treatment.

[14]  R. Mirimanoff,et al.  Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. , 2009, The Lancet. Oncology.

[15]  Yunhui Liu,et al.  Platelet-derived growth factor BB promotes the migration of bone marrow-derived mesenchymal stem cells towards C6 glioma and up-regulates the expression of intracellular adhesion molecule-1 , 2009, Neuroscience Letters.

[16]  C. Glackin,et al.  Neural Stem Cell Tropism to Glioma: Critical Role of Tumor Hypoxia , 2008, Molecular Cancer Research.

[17]  P. Wernet,et al.  Hepatocyte Growth Factor/c-MET Axis-mediated Tropism of Cord Blood-derived Unrestricted Somatic Stem Cells for Neuronal Injury* , 2008, Journal of Biological Chemistry.

[18]  M. Sam Eljamel,et al.  ALA and Photofrin® Fluorescence-guided resection and repetitive PDT in glioblastoma multiforme: a single centre Phase III randomised controlled trial , 2008, Lasers in Medical Science.

[19]  A. Uccelli,et al.  Mesenchymal stem cells in health and disease , 2008, Nature Reviews Immunology.

[20]  M. Andreeff,et al.  Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells , 2008, Gene Therapy.

[21]  Kristjan Plaetzer,et al.  ALA and its clinical impact, from bench to bedside , 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[22]  Jochen Herms,et al.  Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report , 2008, Journal of Neuro-Oncology.

[23]  Y. Mao,et al.  In vivo tracking of superparamagnetic iron oxide nanoparticle-labeled mesenchymal stem cell tropism to malignant gliomas using magnetic resonance imaging. Laboratory investigation. , 2008, Journal of neurosurgery.

[24]  Chu Sheng-hua,et al.  Radiation-enhanced hepatocyte growth factor secretion in malignant glioma cell lines. , 2007, Surgical neurology.

[25]  Qian Peng,et al.  Milestones in the development of photodynamic therapy and fluorescence diagnosis , 2007, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[26]  Margaret Wrensch,et al.  Epidemiology of brain tumors. , 2007, Neurologic clinics.

[27]  Christian Schichor,et al.  Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines , 2007, Journal of Neuro-Oncology.

[28]  Y. Kajimoto,et al.  Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy , 2007, Journal of Neuro-Oncology.

[29]  Henry Hirschberg,et al.  Effects of ALA‐mediated photodynamic therapy on the invasiveness of human glioma cells , 2006, Lasers in surgery and medicine.

[30]  M. Weller,et al.  Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-β-dependent HIF-1α-mediated induction of CXCL12 , 2006 .

[31]  Michael R Hamblin,et al.  Photodynamic therapy and anti-tumour immunity , 2006, Nature Reviews Cancer.

[32]  F. Zanella,et al.  Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. , 2006, The Lancet. Oncology.

[33]  G. Forte,et al.  Hepatocyte Growth Factor Effects on Mesenchymal Stem Cells: Proliferation, Migration, and Differentiation , 2006, Stem cells.

[34]  J. Miyazaki,et al.  A Novel Role of Hepatocyte Growth Factor as an Immune Regulator through Suppressing Dendritic Cell Function1 , 2005, The Journal of Immunology.

[35]  M. Westphal,et al.  Neural stem cell migration toward gliomas in vitro. , 2005, Neuro-oncology.

[36]  J. Laterra,et al.  Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. , 2005, Neuro-oncology.

[37]  E. Bonifacio,et al.  Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. , 2005, Blood.

[38]  M. Andreeff,et al.  Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. , 2005, Cancer research.

[39]  Sabine Neuss,et al.  Functional Expression of HGF and HGF Receptor/c‐met in Adult Human Mesenchymal Stem Cells Suggests a Role in Cell Mobilization, Tissue Repair, and Wound Healing , 2004, Stem cells.

[40]  J. Williams,et al.  Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways. , 2000, Cancer research.

[41]  B. Badie,et al.  In vitro modulation of microglia motility by glioma cells is mediated by hepatocyte growth factor/scatter factor. , 1999, Neurosurgery.

[42]  H. Kataoka,et al.  Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. , 1998, Biochemical and biophysical research communications.

[43]  E. Hudson,et al.  Met and hepatocyte growth factor/scatter factor expression in human gliomas. , 1997, Cancer research.

[44]  M. Weinand,et al.  Scatter factor expression and regulation in human glial tumors , 1996, International journal of cancer.

[45]  H. Tsubouchi,et al.  Effects of hepatocyte growth factor (HGF) on human glioma cells in vitro: HGF acts as a motility factor in glioma cells , 1996, International journal of cancer.

[46]  R. Sutherland Cell and environment interactions in tumor microregions: the multicell spheroid model. , 1988, Science.

[47]  D. Dilloo,et al.  Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cells , 2009, Cellular and Molecular Life Sciences.

[48]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.