Multifaceted Function of MicroRNA-299-3p Fosters an Antitumor Environment Through Modulation of Androgen Receptor and VEGFA Signaling Pathways in Prostate Cancer

[1]  M. Li,et al.  LncRNA CADM1-AS1 serves as a new prognostic biomarker for gastric cancer. , 2019, European review for medical and pharmacological sciences.

[2]  W. Fan,et al.  The role and mechanisms of action of microRNAs in cancer drug resistance , 2019, Clinical Epigenetics.

[3]  X. Chen,et al.  MiR-299-3p functions as a tumor suppressor in thyroid cancer by regulating SHOC2. , 2019, European review for medical and pharmacological sciences.

[4]  Xinghua Jiang,et al.  Knockdown of miR-299-5p inhibits the progression of hepatocellular carcinoma by targeting SIAH1. , 2018, Bulletin du cancer.

[5]  Kunning Wang,et al.  MiR-299-3p functions as a tumor suppressor via targeting Sirtuin 5 in hepatocellular carcinoma. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[6]  Ruiyang Zhao,et al.  MicroRNA-299-3p regulates proliferation, migration and invasion of human ovarian cancer cells by modulating the expression of OCT4. , 2018, Archives of biochemistry and biophysics.

[7]  Jiachang Hu,et al.  Inhibition of microRNA-299-5p sensitizes glioblastoma cells to temozolomide via the MAPK/ERK signaling pathway , 2018, Bioscience reports.

[8]  Yong Dai,et al.  MicroRNA-299-3p suppresses proliferation and invasion by targeting VEGFA in human colon carcinoma. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[9]  N. Seki,et al.  Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer , 2017, British Journal of Cancer.

[10]  Yiqun Shao,et al.  MicroRNA‐218 inhibits tumor growth and increases chemosensitivity to CDDP treatment by targeting BCAT1 in prostate cancer , 2017, Molecular carcinogenesis.

[11]  S. Wölfl,et al.  Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis , 2017, PloS one.

[12]  A. Joshua,et al.  AR Signaling and the PI3K Pathway in Prostate Cancer , 2017, Cancers.

[13]  G. Fraizer,et al.  The Androgen Receptor and VEGF: Mechanisms of Androgen-Regulated Angiogenesis in Prostate Cancer , 2017, Cancers.

[14]  H. Beltran,et al.  Emerging Variants of Castration-Resistant Prostate Cancer , 2017, Current Oncology Reports.

[15]  R. Chakrabarti,et al.  The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer , 2016, Oncotarget.

[16]  Yong Peng,et al.  The role of MicroRNAs in human cancer , 2016, Signal Transduction and Targeted Therapy.

[17]  Steven J. M. Jones,et al.  The Molecular Taxonomy of Primary Prostate Cancer , 2015, Cell.

[18]  Yan Dai,et al.  MicroRNA-299-3p promotes the sensibility of lung cancer to doxorubicin through directly targeting ABCE1. , 2015, International journal of clinical and experimental pathology.

[19]  N. Lu,et al.  A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition , 2015, Cell adhesion & migration.

[20]  A. Zoubeidi,et al.  Targeting the PI3K/Akt pathway in prostate cancer: challenges and opportunities (review). , 2014, International journal of oncology.

[21]  J. Li,et al.  A functional variant in miR-143 promoter contributes to prostate cancer risk , 2014, Archives of Toxicology.

[22]  A. Levine,et al.  MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells , 2014, Oncogene.

[23]  G. Quan,et al.  The Role of Vascular Endothelial Growth Factor in Metastatic Prostate Cancer to the Skeleton , 2013, Prostate cancer.

[24]  Yan Huang,et al.  Identification of Novel AR-Targeted MicroRNAs Mediating Androgen Signalling through Critical Pathways to Regulate Cell Viability in Prostate Cancer , 2013, PloS one.

[25]  G. Fraizer,et al.  Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site , 2013, Molecular Cancer.

[26]  V. Odero-Marah,et al.  The role of Snail in prostate cancer , 2012, Cell adhesion & migration.

[27]  M. Gleave,et al.  Slug, a unique androgen-regulated transcription factor, coordinates androgen receptor to facilitate castration resistance in prostate cancer. , 2012, Molecular endocrinology.

[28]  Shafiq A. Khan,et al.  Vascular endothelial growth factor A, secreted in response to transforming growth factor-β1 under hypoxic conditions, induces autocrine effects on migration of prostate cancer cells. , 2012, Asian journal of andrology.

[29]  K. Jennbacken,et al.  Castration resistant prostate cancer is associated with increased blood vessel stabilization and elevated levels of VEGF and Ang‐2 , 2012, The Prostate.

[30]  Jun Luo,et al.  MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth , 2012, PloS one.

[31]  D. Tindall,et al.  Androgen receptor signaling in prostate cancer development and progression , 2011, Journal of carcinogenesis.

[32]  K. Fizazi,et al.  Targeting Continued Androgen Receptor Signaling in Prostate Cancer , 2011, Clinical Cancer Research.

[33]  Majid I. Alsagabi,et al.  Molecular and Cellular Pathobiology Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression , 2011 .

[34]  S. Leivonen,et al.  Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells. , 2011, Cancer research.

[35]  M. Saegusa,et al.  Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug. , 2009, The American journal of pathology.

[36]  Yutaka Kawakami,et al.  Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. , 2009, Cancer cell.

[37]  D. Bartel MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[38]  R. Vessella,et al.  Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. , 2009, Cancer research.

[39]  B. Olsen,et al.  Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. , 2008, Molecular biology of the cell.

[40]  M. Waltham,et al.  Vimentin and Epithelial-Mesenchymal Transition in Human Breast Cancer – Observations in vitro and in vivo , 2007, Cells Tissues Organs.

[41]  H. Osada,et al.  MicroRNAs in biological processes and carcinogenesis. , 2007, Carcinogenesis.

[42]  Kenneth J. Pienta,et al.  Mechanisms Underlying the Development of Androgen-Independent Prostate Cancer , 2006, Clinical Cancer Research.

[43]  B. Gumbiner,et al.  Regulation of cadherin-mediated adhesion in morphogenesis , 2005, Nature Reviews Molecular Cell Biology.

[44]  T. Byzova,et al.  Metastatic Properties of Prostate Cancer Cells are Controlled by VEGF , 2004, Cell communication & adhesion.

[45]  M. Gleave,et al.  Derivation of androgen‐independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells , 1994, International journal of cancer.