IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling

[1]  L. Bach.  What Happened to the IGF Binding Proteins? , 2018, Endocrinology.

[2]  L. Bach,et al.  40 YEARS OF IGF1: IGF-binding proteins , 2018, Journal of Molecular Endocrinology.

[3]  H. Werner,et al.  Differential expression of IGFBPs in Laron syndrome-derived lymphoblastoid cell lines: Potential correlation with reduced cancer incidence. , 2017, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[4]  A. Gozdzicka-Jozefiak,et al.  Insulin-like growth factor (IGF) axis in cancerogenesis. , 2017, Mutation research. Reviews in mutation research.

[5]  Mohsin Bashir,et al.  Insulin-like growth factor binding protein-2 regulates β-catenin signaling pathway in glioma cells and contributes to poor patient prognosis. , 2016, Neuro-oncology.

[6]  K. Gruden,et al.  Heterogeneous glioblastoma cell cross-talk promotes phenotype alterations and enhanced drug resistance , 2015, Oncotarget.

[7]  C. Decaestecker,et al.  IGF-IR: a new prognostic biomarker for human glioblastoma , 2015, British Journal of Cancer.

[8]  M. Westphal,et al.  Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms. , 2015, Neuro-oncology.

[9]  L. Degraffenried,et al.  The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link , 2015, Front. Endocrinol..

[10]  Wei Zhang,et al.  IGFBP2 potentiates nuclear EGFR-STAT3 signaling , 2015, Oncogene.

[11]  G. Gillespie,et al.  Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas , 2015, Oncotarget.

[12]  L. Bach,et al.  Differential Effects of Insulin-Like Growth Factor Binding Protein-6 (IGFBP-6) on Migration of Two Ovarian Cancer Cell Lines , 2014, Front. Endocrinol..

[13]  A. Wu,et al.  Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway , 2014, British Journal of Cancer.

[14]  P. Kondaiah,et al.  STAT-1 expression is regulated by IGFBP-3 in malignant glioma cells and is a strong predictor of poor survival in patients with glioblastoma. , 2014, Journal of neurosurgery.

[15]  J. Seoane,et al.  Glioblastoma Multiforme: A Look Inside Its Heterogeneous Nature , 2014, Cancers.

[16]  C. Livingstone.  IGF2 and cancer. , 2013, Endocrine-related cancer.

[17]  T. Jiang,et al.  A panel of four cytokines predicts the prognosis of patients with malignant gliomas , 2013, Journal of Neuro-Oncology.

[18]  H. Fathallah-Shaykh,et al.  Prognostic Relevance of Cytochrome c Oxidase in Primary Glioblastoma Multiforme , 2013, PloS one.

[19]  J. Barnholtz-Sloan,et al.  CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. , 2012, Neuro-oncology.

[20]  Zhi Li,et al.  Quorum sensing: How bacteria can coordinate activity and synchronize their response to external signals? , 2012, Protein science : a publication of the Protein Society.

[21]  K. Thennarasu,et al.  Expression Pattern and Prognostic Significance of IGFBP Isoforms in Anaplastic Astrocytoma , 2012, Pathology & Oncology Research.

[22]  Corinne E Griguer,et al.  Acquisition of Chemoresistance in Gliomas Is Associated with Increased Mitochondrial Coupling and Decreased ROS Production , 2011, PloS one.

[23]  P. Lara,et al.  BCL-2, in combination with MVP and IGF-1R expression, improves prediction of clinical outcome in complete response cervical carcinoma patients treated by radiochemotherapy. , 2011, Gynecologic oncology.

[24]  P. Lara,et al.  IGF-1R expression predicts clinical outcome in patients with locally advanced oral squamous cell carcinoma. , 2011, Oral oncology.

[25]  J. Sarkaria,et al.  Establishment, Maintenance, and In Vitro and In Vivo Applications of Primary Human Glioblastoma Multiforme (GBM) Xenograft Models for Translational Biology Studies and Drug Discovery , 2011, Current protocols in pharmacology.

[26]  G. Sauter,et al.  Insulin‐like growth factor‐1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus , 2010, International journal of cancer.

[27]  J. Sarkaria,et al.  Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain* , 2010, The Journal of Biological Chemistry.

[28]  K. Thennarasu,et al.  Grade-Specific Expression of Insulin-like Growth Factor–Binding Proteins-2, -3, and -5 in Astrocytomas: IGFBP-3 Emerges as a Strong Predictor of Survival in Patients with Newly Diagnosed Glioblastoma , 2010, Cancer Epidemiology, Biomarkers & Prevention.

[29]  C. Turnbough,et al.  CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages , 2009, Proceedings of the National Academy of Sciences.

[30]  Ken Kato,et al.  Impact of Insulin-Like Growth Factor Type 1 Receptor, Epidermal Growth Factor Receptor, and HER2 Expressions on Outcomes of Patients with Gastric Cancer , 2008, Clinical Cancer Research.

[31]  Hiroaki Kataoka,et al.  Roles of insulin-like growth factor binding protein-2 (IGFBP-2) in glioblastoma. , 2007, Anticancer research.

[32]  P. Fu,et al.  Promotion of Cancer Cell Migration , 2007, Journal of Biological Chemistry.

[33]  S. Horvath,et al.  Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer , 2007, Proceedings of the National Academy of Sciences.

[34]  Zora Modrusan,et al.  Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma , 2007, Proceedings of the National Academy of Sciences.

[35]  D. Carbone,et al.  Insulin-like growth factor-I receptor as a marker for prognosis and a therapeutic target in human esophageal squamous cell carcinoma. , 2006, Carcinogenesis.

[36]  C. James,et al.  Use of an Orthotopic Xenograft Model for Assessing the Effect of Epidermal Growth Factor Receptor Amplification on Glioblastoma Radiation Response , 2006, Clinical Cancer Research.

[37]  Thomas D. Wu,et al.  Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. , 2006, Cancer cell.

[38]  L. Bach.  IGFBP-6 five years on; not so 'forgotten'? , 2005, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[39]  T. Oyama,et al.  Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer , 2005, British Journal of Cancer.

[40]  U. Schüller,et al.  Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. , 2005, The American journal of pathology.

[41]  S. Horvath,et al.  Gene Expression Profiling of Gliomas Strongly Predicts Survival , 2004, Cancer Research.

[42]  S. Hankinson,et al.  Insulin-like growth factors and neoplasia , 2004, Nature Reviews Cancer.

[43]  Matthias Egger,et al.  Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis , 2004, The Lancet.

[44]  C. Lassarre,et al.  Insulin-like growth factor binding protein-6 inhibits neuroblastoma cell proliferation and tumour development. , 2002, European journal of cancer.

[45]  A. Scott,et al.  Overexpression of insulin‐like growth factor binding protein‐6 inhibits rhabdomyosarcoma growth in vivo , 2001, International journal of cancer.

[46]  Jian Li,et al.  Growth hormone and insulin-like growth factor-I: effects on the growth of glioma cell lines. , 2001, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[47]  R. Whitehead,et al.  Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells , 2001, Molecular and Cellular Endocrinology.

[48]  V. Hwa,et al.  The Insulin-like Growth Factor-binding Protein (igfbp) Superfamily* , 2022 .

[49]  H. Antoniades,et al.  Expression of insulin‐like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry , 1992, International journal of cancer.

[50]  H. Holst,et al.  The expression of insulin-like growth factor I and insulin-like growth factor II genes in the human fetal and adult brain and in glioma , 1988, Neuroscience Letters.

[51]  R. Verhaak,et al.  GlioVis data portal for visualization and analysis of brain tumor expression datasets. , 2017, Neuro-oncology.

[52]  J. Sarkaria,et al.  Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation. , 2016, Neuro-oncology.

[53]  J. Barnholtz-Sloan,et al.  CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009-2013. , 2016, Neuro-oncology.

[54]  P. Fu,et al.  PROMOTION OF CANCER CELL MIGRATION: AN INSULIN-LIKE GROWTH FACTOR (IGF)-INDEPENDENT ACTION OF IGF-BINDING PROTEIN-6 , 2007 .

[55]  L. Bach.  Insulin-Like Growth Factor Binding Protein-6: The “Forgotten” Binding Protein? , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.