Disease-specific transcriptional programs govern airway goblet cell metaplasia
暂无分享,去创建一个
Kuan Li | Qing Yue | Qi Wang | Zhaoyu Song | Yu Li | Yu Zhu | Huaiyong Chen
[1] K. Kuwano,et al. Anomalous Epithelial Variations and Ectopic Inflammatory Response in Chronic Obstructive Pulmonary Disease. , 2022, American journal of respiratory cell and molecular biology.
[2] G. Parisi,et al. Cystic Fibrosis and Oxidative Stress: The Role of CFTR , 2022, Molecules.
[3] J. Qu,et al. A single-cell transcriptomic landscape of the lungs of patients with COVID-19 , 2021, Nature Cell Biology.
[4] Praveer P Sharma,et al. Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development , 2021, Cell reports.
[5] I. Adcock,et al. Molecular mechanisms of oxidative stress in asthma. , 2021, Molecular aspects of medicine.
[6] A. Molino,et al. MAPK15-ULK1 signaling regulates mitophagy of airway epithelial cell in chronic obstructive pulmonary disease. , 2021, Free radical biology & medicine.
[7] M. Welsh,et al. Inflammatory cytokines TNFα and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators. , 2021, The Journal of clinical investigation.
[8] Dave Singh,et al. Type‐2 airway inflammation in mild asthma patients with high blood eosinophils and high fractional exhaled nitric oxide , 2021, Clinical and translational science.
[9] J. Whitsett,et al. VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. , 2021, Developmental cell.
[10] Jianhai Wang,et al. Inhibition of Gabrp reduces the differentiation of airway epithelial progenitor cells into goblet cells , 2021, Experimental and therapeutic medicine.
[11] J. Ernst,et al. Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition , 2021, Nature Medicine.
[12] André F. Rendeiro,et al. A molecular single-cell lung atlas of lethal COVID-19 , 2021, Nature.
[13] Yunpeng Liu,et al. Interferon regulatory factor 6 correlates with the progression of non-small cell lung cancer and can be regulated by miR-320. , 2021, The Journal of pharmacy and pharmacology.
[14] Ariel J. Levine,et al. Confronting false discoveries in single-cell differential expression , 2021, Nature Communications.
[15] R. Hewitt,et al. Regulation of immune responses by the airway epithelial cell landscape , 2021, Nature Reviews Immunology.
[16] X. Nie,et al. Inflammation accelerates copper‐mediated cytotoxicity through induction of six‐transmembrane epithelial antigens of prostate 4 expression , 2020, Immunology and cell biology.
[17] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[18] L. Fairclough,et al. The role of CD8 + T lymphocytes in chronic obstructive pulmonary disease: a systematic review , 2020, Inflammation research : official journal of the European Histamine Research Society ... [et al.].
[19] J. Nawroth,et al. Stem Cells and Lung Regeneration. , 2020, American journal of physiology. Cell physiology.
[20] G. Washko,et al. Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis , 2020, Science Advances.
[21] P. Hellings,et al. Epithelial barriers in allergy and asthma , 2020, Journal of Allergy and Clinical Immunology.
[22] G. Tearney,et al. Novel Therapy of Bicarbonate, Glutathione and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport. , 2020, American journal of respiratory cell and molecular biology.
[23] P. Barnes. Oxidative stress-based therapeutics in COPD , 2020, Redox biology.
[24] Shawn Choe,et al. Inactivation of FOXA2 by Respiratory Bacterial Pathogens and Dysregulation of Pulmonary Mucus Homeostasis , 2020, Frontiers in Immunology.
[25] Min Hong,et al. EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice , 2020, Mucosal Immunology.
[26] Kamil Slowikowski,et al. Fast, sensitive, and accurate integration of single cell data with Harmony , 2019, Nature Methods.
[27] Irving L. Weissman,et al. A molecular cell atlas of the human lung from single cell RNA sequencing , 2019, Nature.
[28] L. Ulloa,et al. Transgelin-2: Biochemical and Clinical Implications in Cancer and Asthma. , 2019, Trends in biochemical sciences.
[29] P. Berger,et al. Chemokines in COPD: From Implication to Therapeutic Use , 2019, International journal of molecular sciences.
[30] Fabian J Theis,et al. A cellular census of human lungs identifies novel cell states in health and in asthma , 2019, Nature Medicine.
[31] J. Whitsett. Airway Epithelial Differentiation and Mucociliary Clearance. , 2018, Annals of the American Thoracic Society.
[32] R. Shaykhiev,et al. Emerging biology of persistent mucous cell hyperplasia in COPD , 2018, Thorax.
[33] D. Veale,et al. Hypoxia, oxidative stress and inflammation. , 2018, Free radical biology & medicine.
[34] Aviv Regev,et al. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes , 2018, Nature.
[35] J. Lee,et al. Single-cell RNA sequencing technologies and bioinformatics pipelines , 2018, Experimental & Molecular Medicine.
[36] C. Xu,et al. High expression of sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia , 2018, Mucosal Immunology.
[37] C. Emala,et al. The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium , 2018, Respiratory Research.
[38] P. Howarth,et al. Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma , 2017, American journal of respiratory cell and molecular biology.
[39] Hannah A. Pliner,et al. Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.
[40] D. Meyerholz,et al. Gel-forming mucins form distinct morphologic structures in airways , 2017, Proceedings of the National Academy of Sciences.
[41] J. Aerts,et al. SCENIC: Single-cell regulatory network inference and clustering , 2017, Nature Methods.
[42] J. Whitsett,et al. The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice , 2017, Science Signaling.
[43] P. Barnes,et al. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. , 2016, The Journal of allergy and clinical immunology.
[44] J. Mims. Asthma: definitions and pathophysiology , 2015, International forum of allergy & rhinology.
[45] Géraldine Guasch,et al. Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia. , 2015, Trends in molecular medicine.
[46] M. Konstan,et al. Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy. , 2015, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
[47] H. Kerstjens,et al. Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells , 2015, Thorax.
[48] Amy Y. Chen,et al. Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung. , 2015, Cell reports.
[49] C. Delacourt,et al. Cellular and molecular mechanisms of goblet cell metaplasia in the respiratory airways , 2013, Experimental lung research.
[50] Justin Guinney,et al. GSVA: gene set variation analysis for microarray and RNA-Seq data , 2013, BMC Bioinformatics.
[51] S. Plafker,et al. Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells. , 2012, American journal of physiology. Lung cellular and molecular physiology.
[52] V. Kaartinen,et al. Notch Signaling Prevents Mucous Metaplasia in Mouse Conducting Airways during Postnatal Development , 2011, Pediatric Research.
[53] Carla M. T. Bauer,et al. Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke. , 2011, American journal of respiratory and critical care medicine.
[54] J. Fahy,et al. Airway mucus function and dysfunction. , 2010, The New England journal of medicine.
[55] D. Harrison,et al. Faculty Opinions recommendation of CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. , 2010 .
[56] H. Schulz,et al. Effects of ultrafine particles-induced oxidative stress on Clara cells in allergic lung inflammation , 2010, Particle and Fibre Toxicology.
[57] Davis J. McCarthy,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[58] M. Holtzman,et al. Involvement of the p38 MAPK pathway in IL‐13‐induced mucous cell metaplasia in mouse tracheal epithelial cells , 2008, Respirology.
[59] S. Randell,et al. Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. , 2008, American journal of respiratory cell and molecular biology.
[60] A. M. Houghton,et al. CD8+ T Cells Are Required for Inflammation and Destruction in Cigarette Smoke-Induced Emphysema in Mice1 , 2007, The Journal of Immunology.
[61] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[62] Marc A. Thomas,et al. Defective Activation of c-Src in Cystic Fibrosis Airway Epithelial Cells Results in Loss of Tumor Necrosis Factor-α-induced Gap Junction Regulation* , 2003, The Journal of Biological Chemistry.
[63] R. Katoh,et al. TGF-beta signaling may play a role in the development of goblet cell hyperplasia in a mouse model of allergic rhinitis. , 2010, Allergology international : official journal of the Japanese Society of Allergology.