Oxidative, inflammatory and immunologic status in children with undescended testes

Background:  In order to better understand the pathogenesis of risk of future sub‐/infertility in children with undescended testes (UDT), we designed this prospective study to examine the oxidative stress, inflammatory response and autoimmunity in children with UDT. We examined the concentrations of malondialdehyde (MDA), interleukin‐6 (IL‐6) and antisperm antibodies (ASA) in children with UDT and healthy controls.

[1]  P. Lainas,et al.  Effect of testis nondescent or orchidopexy on antisperm antibodies and testis histology in rats. , 2010, Fertility and sterility.

[2]  K. Shiraishi,et al.  Elevated scrotal temperature, but not varicocele grade, reflects testicular oxidative stress-mediated apoptosis , 2010, World Journal of Urology.

[3]  S. Seshadri,et al.  ORIGINAL ARTICLE: The Role of Cytokine Expression in Different Subgroups of Subfertile Men , 2009, American journal of reproductive immunology.

[4]  J. Lysiak,et al.  Oxidative stress: a common factor in testicular dysfunction. , 2008, Journal of andrology.

[5]  J. Morrow,et al.  Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease , 2008, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[6]  A. Agarwal,et al.  REVIEW ARTICLE: Clinical Relevance of Oxidative Stress in Male Factor Infertility: An Update , 2007, American journal of reproductive immunology.

[7]  P. Puri,et al.  Orchidopexy and its impact on fertility , 2007, Pediatric Surgery International.

[8]  P. Reddanna,et al.  Bacterial lipopolysaccharide-induced oxidative stress in the impairment of steroidogenesis and spermatogenesis in rats. , 2006, Reproductive toxicology.

[9]  A. Agarwal,et al.  Reactive oxygen species as an independent marker of male factor infertility. , 2006, Fertility and sterility.

[10]  M. Kurpisz,et al.  ANTISPERM ANTIBODIES IN PREPUBERTAL BOYS WITH CRYPTORCHIDISM , 2006, Archives of andrology.

[11]  E. Nieschlag,et al.  Interleukin-6 expression during normal maturation of the mouse testis. , 2005, European cytokine network.

[12]  Michael E. Chen,et al.  Antisperm antibodies in cryptorchid boys , 2005, European Journal of Pediatrics.

[13]  A. Agarwal,et al.  Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele. , 2004, Urology.

[14]  K. Schnakenburg,et al.  Adult height of patients treated in childhood for undescended testes , 1977, European Journal of Pediatrics.

[15]  R. Lala,et al.  Testicular function in men treated in childhood for undescended testes. , 2001, Journal of pediatric surgery.

[16]  Fisch,et al.  The undescended testis: considerations and impact on fertility , 1999, BJU international.

[17]  F. Orio,et al.  Antisperm antibodies in cryptorchidism before and after surgery. , 1998, The Journal of urology.

[18]  I. Huhtaniemi,et al.  Abdominal position of the rat testis is associated with high level of lipid peroxidation. , 1995, Biology of reproduction.

[19]  K. Yagi Lipid peroxides and related radicals in clinical medicine. , 1994, Advances in experimental medicine and biology.