A Pragmatic Definition of Therapeutic Synergy Suitable for Clinically Relevant In Vitro Multicompound Analyses
暂无分享,去创建一个
Ulf Hammerling | Magnus Åberg | Muhammad Kashif | Rolf Larsson | Mats G Gustafsson | Peter Nygren | Claes Andersson | Tobias Sjöblom | T. Sjöblom | M. Kashif | C. Andersson | M. Gustafsson | R. Larsson | P. Nygren | U. Hammerling | Magnus Åberg
[1] W H Carter,et al. Combination chemotherapy: arriving at optimal treatment levels by incorporating side effect constraints. , 1978, Cancer treatment reports.
[2] N. Mantel,et al. The employment of combinations of drugs in the chemotherapy of neoplasia: a review. , 1957, Cancer research.
[3] John A. Nelder,et al. A Simplex Method for Function Minimization , 1965, Comput. J..
[4] S. Loewe. The problem of synergism and antagonism of combined drugs. , 1953, Arzneimittel-Forschung.
[5] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[6] P. Lee,et al. Regression Analysis of Survival Data in Cancer Chemotherapy , 1984 .
[7] Elin Lindhagen,et al. The fluorometric microculture cytotoxicity assay , 2008, Nature Protocols.
[8] Michael Dick,et al. “The whole is greater than the sum of the parts“ , 2010 .
[9] D I Tang,et al. Classification of the effectiveness of combination treatments. , 1997, Statistics in medicine.
[10] S N Steen. Therapeutic synergism. , 1978, Chest.
[11] M. Berenbaum. What is synergy? , 1989, Pharmacological reviews.
[12] S R HUMPHREYS,et al. Combined treatment of advanced leukemia (L1210) in mice with amethopterin and 6-mercaptopurine. , 1956, Journal of the National Cancer Institute.
[13] W R Greco,et al. The search for cytotoxic synergy between anticancer agents: a case of Dorothy and the ruby slippers? , 1996, Journal of the National Cancer Institute.
[14] S. Loewe,et al. Über Kombinationswirkungen , 1926, Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie.
[15] M. Morari,et al. A New Model for Drug Interactions and Optimal Drug Dosing , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.
[16] B. Stockwell,et al. Multicomponent therapeutics for networked systems , 2005, Nature Reviews Drug Discovery.
[17] P. Sorger,et al. Systems biology and combination therapy in the quest for clinical efficacy , 2006, Nature chemical biology.
[18] Ross L. Prentice,et al. Regression Analysis of Survival Data in Cancer Chemotherapy. , 1984 .
[19] G. Box. The Exploration and Exploitation of Response Surfaces: Some General Considerations and Examples , 1954 .
[20] Manfred Morari,et al. The Well-being Model: A New Drug Interaction Model for Positive and Negative Effects , 2006, Anesthesiology.
[21] W. H. Carter,et al. An improved method for analyzing survival data from combination chemotherapy experiments. , 1979, Cancer research.
[22] N Mantel,et al. Evaluation of combination chemotherapy with three drugs. , 1968, Cancer research.
[23] W. Greco,et al. The search for synergy: a critical review from a response surface perspective. , 1995, Pharmacological reviews.
[24] Wampler Gl,et al. Combination chemotherapy: arriving at optimal treatment levels by incorporating side effect constraints. , 1978 .
[25] J. Lehár,et al. Systematic discovery of multicomponent therapeutics , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[26] Ting-Chao Chou,et al. Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies , 2006, Pharmacological Reviews.
[27] J. Lehár,et al. Multi-target therapeutics: when the whole is greater than the sum of the parts. , 2007, Drug discovery today.
[28] W. H. Carter,et al. Titrating and evaluating multi‐drug regimens within subjects , 2003, Statistics in medicine.
[29] W H Carter,et al. On determining the levels of treatment to optimize the probability of a favorable response. , 1977, Cancer treatment reports.
[30] Berenbaum Mc. What is synergy? , 1989, Pharmacological reviews.
[31] E D Campbell,et al. Drug activity and therapeutic synergism in cancer treatment. , 1982, Cancer research.
[32] M C Berenbaum. Synergy and antagonism are not synonymous with therapeutic advantage and disadvantage. , 1988, The Journal of antimicrobial chemotherapy.
[33] J. Dancey,et al. Strategies for optimizing combinations of molecularly targeted anticancer agents , 2006, Nature Reviews Drug Discovery.
[34] W. H. Carter,et al. Confidence regions for constrained optima in response-surface experiments. , 1983, Biometrics.
[35] C. I. Bliss. THE TOXICITY OF POISONS APPLIED JOINTLY1 , 1939 .
[36] H. Sugerman,et al. Association between Incident Cancer and Subsequent Stroke , 2015, Annals of neurology.