A Protocol for the Diagnosis of Autism Spectrum Disorder Structured in Machine Learning and Verbal Decision Analysis

Autism Spectrum Disorder is a mental disorder that afflicts millions of people worldwide. It is estimated that one in 160 children has traces of autism, with five times the higher prevalence in boys. The protocols for detecting symptoms are diverse. However, the following are among the most used: the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5), of the American Psychiatric Association; the Revised Autistic Diagnostic Observation Schedule (ADOS-R); the Autistic Diagnostic Interview (ADI); and the International Classification of Diseases, 10th edition (ICD-10), published by the World Health Organization (WHO) and adopted in Brazil by the Unified Health System (SUS). The application of machine learning models helps make the diagnostic process of Autism Spectrum Disorder more precise, reducing, in many cases, the number of criteria necessary for evaluation, denoting a form of attribute engineering (feature engineering) efficiency. This work proposes a hybrid approach based on machine learning algorithms' composition to discover knowledge and concepts associated with the multicriteria method of decision support based on Verbal Decision Analysis to refine the results. Therefore, the study has the general objective of evaluating how the mentioned hybrid methodology proposal can make the protocol derived from ICD-10 more efficient, providing agility to diagnosing Autism Spectrum Disorder by observing a minor symptom. The study database covers thousands of cases of people who, once diagnosed, obtained government assistance in Brazil.

[1]  Plácido Rogério Pinheiro,et al.  A Hybrid Model to Guide the Consultation of Children with Autism Spectrum Disorder , 2019, RIIFORUM.

[2]  Plácido Rogério Pinheiro,et al.  Evaluation of the Alzheimer's disease clinical stages under the optics of hybrid approaches in Verbal Decision Analysis , 2017, Telematics Informatics.

[3]  Plácido Rogério Pinheiro,et al.  Project management aided by verbal decision analysis approaches: a case study for the selection of the best SCRUM practices , 2015, Int. Trans. Oper. Res..

[4]  Jean-Philippe Vert,et al.  Consistency of Random Forests , 2014, 1405.2881.

[5]  Z. Warren,et al.  Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016 , 2020, Morbidity and mortality weekly report. Surveillance summaries.

[6]  Fadi Thabtah,et al.  A new machine learning model based on induction of rules for autism detection , 2020, Health Informatics J..

[7]  Wei-Yin Loh,et al.  Classification and regression trees , 2011, WIREs Data Mining Knowl. Discov..

[8]  A. Brereton,et al.  Providing an Independent Second Opinion for the Diagnosis of Autism Using Artificial Intelligence over the Internet , 2009 .

[9]  Ira L. Cohen,et al.  An artificial neural network analogue of learning in autism , 1994, Biological Psychiatry.

[10]  Yi Lin,et al.  AN EFFECTIVE METHOD FOR HIGH-DIMENSIONAL LOG-DENSITY ANOVA ESTIMATION, WITH APPLICATION TO NONPARAMETRIC GRAPHICAL MODEL BUILDING , 2006 .

[11]  Cícero Nogueira dos Santos,et al.  A Hybrid Approach of Verbal Decision Analysis and Machine Learning , 2012, RSCTC.

[12]  Erwan Scornet,et al.  A random forest guided tour , 2015, TEST.

[13]  Carolina Lampreia Avaliações quantitativa e qualitativa de um menino autista: uma análise crítica , 2003 .

[14]  Ira L. Cohen,et al.  A neural network approach to the classification of autism , 1993, Journal of autism and developmental disorders.

[15]  Oleg I. Larichev,et al.  Verbal Decision Analysis for Unstructured Problems , 1997 .

[16]  Eric Fombonne,et al.  Brief Report: Prevalence of Pervasive Developmental Disorder in Brazil: A Pilot Study , 2011, Journal of autism and developmental disorders.

[17]  G. Arbanas Diagnostic and Statistical Manual of Mental Disorders (DSM-5) , 2015 .

[18]  Amir Ali Bagherzadeh,et al.  Developing Autism Screening Expert System (ASES) , 2013 .

[19]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[20]  A. Boonen,et al.  The international classification for functioning, disability and health , 2007, Clinical Rheumatology.

[21]  Martin Mozina,et al.  Orange: data mining toolbox in python , 2013, J. Mach. Learn. Res..

[22]  H. Faras,et al.  Autism spectrum disorders , 2010, Annals of Saudi medicine.

[23]  Leo Breiman,et al.  Bagging Predictors , 1996, Machine Learning.

[24]  F. Thabtah Machine learning in autistic spectrum disorder behavioral research: A review and ways forward , 2019, Informatics for health & social care.

[25]  Fadi Thabtah,et al.  Autism Spectrum Disorder Screening: Machine Learning Adaptation and DSM-5 Fulfillment , 2017, ICMHI.

[26]  Adriano Bessa Albuquerque,et al.  A Multicriteria Approach to Support Task Allocation in Projects of Distributed Software Development , 2019, Complex..