Use of optical biosensors for the study of mechanistically concerted surface adsorption processes.

The advent of commercial optical biosensors, such as the BIAcore from Pharmacia and IAsys from Affinity Sensors, has made available to the biochemist a powerful means to examine and characterize the interaction of biological macromolecules with a binding surface. By analysis of the kinetic and equilibrium aspects of the observed experimental adsorption isotherms, rate and affinity constants can be determined. This Review focuses on pertinent aspects of the technology and its use for the performance and quantitative characterization of some various types of mechanistically concerted adsorption behavior.

[1]  E. Nice,et al.  Analysis of the binding of the Fab fragment of monoclonal antibody NC10 to influenza virus N9 neuraminidase from tern and whale using the BIAcore biosensor: effect of immobilization level and flow rate on kinetic analysis. , 1999, Analytical biochemistry.

[2]  D. Williams,et al.  Kinetic analysis of antibody-antigen interactions at a supported lipid monolayer. , 1999, Analytical biochemistry.

[3]  S. Ravichandran,et al.  Mobility of adsorbed proteins: a Brownian dynamics study. , 2000, Biophysical journal.

[4]  J. Hoebeke,et al.  Analysis of human CD4-antibody interaction using the BIAcore system. , 1995, Journal of immunological methods.

[5]  R. Karlsson,et al.  Experimental design for kinetic analysis of protein-protein interactions with surface plasmon resonance biosensors. , 1997, Journal of immunological methods.

[6]  M C Davies,et al.  Surface plasmon resonance for real time in situ analysis of protein adsorption to polymer surfaces. , 1997, Biomaterials.

[7]  H. Macleod,et al.  Conformational changes in rhodopsin probed by surface plasmon resonance spectroscopy. , 1994, Biochemistry.

[8]  F. Veer,et al.  Ellipsometry as a tool to study the adsorption behavior of synthetic and biopolymers at the air–water interface , 1978 .

[9]  J. Witz.  Kinetic analysis of analyte binding by optical biosensors: hydrodynamic penetration of the analyte flow into the polymer matrix reduces the influence of mass transport. , 1999, Analytical biochemistry.

[10]  J. Ramsden,et al.  Unmyristoylated MARCKS-related protein (MRP) binds to supported planar phosphatidylcholine membranes. , 1998, Biochimica et biophysica acta.

[11]  H. J. Griesser,et al.  Effect of charged groups on the adsorption and penetration of proteins onto and into carboxymethylated poly(HEMA) hydrogels. , 1998, Biomaterials.

[12]  M. Hämäläinen,et al.  Identification and optimization of regeneration conditions for affinity-based biosensor assays. A multivariate cocktail approach. , 1999, Analytical chemistry.

[13]  Andreas Brecht,et al.  PROTEIN INTERACTIONS IN COVALENTLY ATTACHED DEXTRAN LAYERS , 1999 .

[14]  R. Karlsson,et al.  Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. , 1991, BioTechniques.

[15]  G M Whitesides,et al.  A strategy for the generation of surfaces presenting ligands for studies of binding based on an active ester as a common reactive intermediate: a surface plasmon resonance study. , 1999, Analytical chemistry.

[16]  R. Karlsson,et al.  Biomolecular interaction analysis: affinity biosensor technologies for functional analysis of proteins. , 1997, Current opinion in chemical biology.

[17]  D. Myszka,et al.  Improving biosensor analysis , 1999, Journal of molecular recognition : JMR.

[18]  P. Schuck,et al.  Reliable determination of binding affinity and kinetics using surface plasmon resonance biosensors. , 1997, Current opinion in biotechnology.

[19]  C. Niemeyer,et al.  Hybridization characteristics of biomolecular adaptors, covalent DNA--streptavidin conjugates. , 1998, Bioconjugate chemistry.

[20]  Z. Salamon,et al.  Low concentrations of diacylglycerol promote the binding of apolipophorin III to a phospholipid bilayer: a surface plasmon resonance spectroscopy study. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Mccoy,et al.  A plasmid expression system for quantitative in vivo biotinylation of thioredoxin fusion proteins in Escherichia coli. , 1998, Nucleic acids research.

[22]  K. Chittur.  Surface techniques to examine the biomaterial-host interface: an introduction to the papers. , 1998, Biomaterials.

[23]  A. H. Severs,et al.  Enhanced surface plasmon resonance inhibition test (ESPRIT) using latex particles , 1993 .

[24]  Tendler,et al.  Screening the Biointeractions of Submicron Sized Particles Intended for Site-Specific Delivery Using Surface Plasmon Resonance. , 1999, Journal of colloid and interface science.

[25]  D G Myszka,et al.  Extending the range of rate constants available from BIACORE: interpreting mass transport-influenced binding data. , 1998, Biophysical journal.

[26]  B. Goldstein,et al.  The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore , 1999, Journal of molecular recognition : JMR.

[27]  B. Persson,et al.  Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins , 1991 .

[28]  J. Ramsden,et al.  Experimental methods for investigating protein adsorption kinetics at surfaces , 1994, Quarterly Reviews of Biophysics.

[29]  E C Nice,et al.  Micropreparative ligand fishing with a cuvette-based optical mirror resonance biosensor. , 2000, Journal of chromatography. A.

[30]  D G Myszka,et al.  Global analysis of a macromolecular interaction measured on BIAcore. , 1996, Biochemical and biophysical research communications.

[31]  B Kasemo,et al.  Monte Carlo simulation of diffusion of adsorbed proteins , 2000, Proteins.

[32]  R. Karlsson,et al.  Kinetic and Concentration Analysis Using BIA Technology , 1994 .

[33]  L. D. Ward,et al.  Effects of solute multivalence on the evaluation of binding constants by biosensor technology: studies with concanavalin A and interleukin-6 as partitioning proteins. , 1995, Analytical biochemistry.

[34]  S. Loefas,et al.  Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors. , 1991, Analytical biochemistry.

[35]  D. Josić,et al.  Use of surface plasmon resonance for studies of protein-protein and protein-phospholipid membrane interactions. Application to the binding of factor VIII to von Willebrand factor and to phosphatidylserine-containing membranes. , 1999, Journal of chromatography. A.

[36]  A. Plant,et al.  Phospholipid/alkanethiol bilayers for cell-surface receptor studies by surface plasmon resonance. , 1995, Analytical biochemistry.

[37]  I. Lundström.  Models of protein adsorption on solid surfaces , 1985 .

[38]  R J Leatherbarrow,et al.  Second-order kinetic analysis of IAsys biosensor data: its use and applicability. , 1998, Analytical biochemistry.

[39]  I. Lundström,et al.  Simple kinetic models for protein exchange reactions on solid surfaces , 1990 .

[40]  R. Karlsson,et al.  Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors. , 1994, Analytical biochemistry.

[41]  D. Millar,et al.  Determination of binding constants by equilibrium titration with circulating sample in a surface plasmon resonance biosensor. , 1998, Analytical biochemistry.

[42]  S. Smith‐Gill,et al.  Experimental design for analysis of complex kinetics using surface plasmon resonance. , 2000, Methods.

[43]  G. S. Rushbrooke.  Introduction to statistical mechanics , 1949 .

[44]  J. Cronin,et al.  The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions Part I: Principle of operation and associated instrumentation , 1992 .

[45]  A. Minton.  Adsorption of globular proteins on locally planar surfaces. II. Models for the effect of multiple adsorbate conformations on adsorption equilibria and kinetics. , 1999, Biophysical journal.

[46]  P. Wojciechowski,et al.  A computer simulation for the study of macromolecular adsorption with special applications to single-component protein adsorption , 1990 .

[47]  R. Marchant,et al.  Atomic force microscopy for characterization of the biomaterial interface. , 1998, Biomaterials.

[48]  Caruso,et al.  Characterization of Ferritin Adsorption onto Gold , 1997, Journal of colloid and interface science.

[49]  R. J. Green,et al.  Competitive protein adsorption as observed by surface plasmon resonance. , 1999, Biomaterials.

[50]  R W Glaser,et al.  Antigen-antibody binding and mass transport by convection and diffusion to a surface: a two-dimensional computer model of binding and dissociation kinetics. , 1993, Analytical biochemistry.

[51]  P. Garland,et al.  Optical evanescent wave methods for the study of biomolecular interactions , 1996, Quarterly Reviews of Biophysics.

[52]  Brusatori,et al.  A Kinetic Model of Protein Adsorption/Surface-Induced Transition Kinetics Evaluated by the Scaled Particle Theory. , 1999, Journal of colloid and interface science.

[53]  Julian Talbot,et al.  Surface exclusion effects in adsorption processes , 1989 .

[54]  H A Macleod,et al.  Surface plasmon resonance spectroscopy as a tool for investigating the biochemical and biophysical properties of membrane protein systems. I: Theoretical principles. , 1997, Biochimica et biophysica acta.

[55]  N.-H. Linda Wang,et al.  Irreversible adsorption on nonuniform surfaces: the random site model , 1993 .

[56]  R. Karlsson,et al.  Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. , 1991, Journal of immunological methods.

[57]  E S Ward,et al.  The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments. , 1999, Analytical biochemistry.

[58]  Z. Diénès,et al.  Incorporation of rhodopsin in laterally structured supported membranes: observation of transducin activation with spatially and time-resolved surface plasmon resonance. , 1998, Biochemistry.

[59]  J. Meléndez,et al.  Detection of DNA hybridization using the TISPR-1 surface plasmon resonance biosensor. , 1999, Analytical biochemistry.

[60]  A. Szabó,et al.  Surface plasmon resonance and its use in biomolecular interaction analysis (BIA). , 1995, Current opinion in structural biology.

[61]  L. Nieba,et al.  Competition BIAcore for measuring true affinities: large differences from values determined from binding kinetics. , 1996, Analytical biochemistry.

[62]  W. Reichert,et al.  Planar integrated optical methods for examining thin films and their surface adlayers. , 1998, Biomaterials.

[63]  D. O'Shannessy,et al.  Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector. , 1992, Analytical biochemistry.

[64]  B. Widom,et al.  Some Topics in the Theory of Fluids , 1963 .

[65]  A S Perelson,et al.  Steric effects on multivalent ligand-receptor binding: exclusion of ligand sites by bound cell surface receptors. , 1999, Biophysical journal.

[66]  C. Horváth,et al.  Retention in reversed-phase chromatography: partition or adsorption? , 1998, Journal of chromatography. A.

[67]  David G. Myszka,et al.  HuD RNA Recognition Motifs Play Distinct Roles in the Formation of a Stable Complex with AU-Rich RNA , 2000, Molecular and Cellular Biology.

[68]  K Andersson,et al.  Kinetic characterization of the interaction of the Z‐fragment of protein A with mouse‐IgG3 in a volume in chemical space , 1999, Proteins.

[69]  W. Sawyer,et al.  Effects of charged lipids on the interaction of cholesteryl ester transfer protein with lipid microemulsions. , 1997, The Biochemical journal.

[70]  D. Laune,et al.  Dissection of an antibody paratope into peptides discloses the idiotope recognized by the cognate anti-idiotypic antibody. , 2000, Journal of immunological methods.

[71]  D. Winzor,et al.  Use of a resonant mirror biosensor to characterize the interaction of carboxypeptidase A with an elicited monoclonal antibody. , 1997, Analytical biochemistry.

[72]  W. Hennink,et al.  Interaction between plasmid DNA and cationic polymers studied by surface plasmon resonance spectrometry , 1999 .

[73]  T. Barrowcliffe,et al.  Phospholipid binding of factor VIII in different therapeutic concentrates , 1999, British journal of haematology.

[74]  C. Price,et al.  Real-time analysis of cell surface HLA class I interactions. , 1998, Biosensors & bioelectronics.

[75]  Howard Reiss,et al.  Statistical Mechanics of Rigid Spheres , 1959 .

[76]  R. Kelley,et al.  Thermodynamic analysis of an antibody functional epitope. , 1993, Biochemistry.

[77]  D. Marsh,et al.  Protein surface-distribution and protein-protein interactions in the binding of peripheral proteins to charged lipid membranes. , 1995, Biophysical journal.

[78]  M. Fischer,et al.  Kinetic analysis of the mass transport limited interaction between the tyrosine kinase lck SH2 domain and a phosphorylated peptide studied by a new cuvette-based surface plasmon resonance instrument. , 2000, Analytical biochemistry.

[79]  D. Winzor,et al.  Studies of protein interactions by biosensor technology: an alternative approach to the analysis of sensorgrams deviating from pseudo-first-order kinetic behavior. , 1997, Analytical biochemistry.

[80]  Z. Salamon,et al.  Surface plasmon resonance studies of complex formation between cytochrome c and bovine cytochrome c oxidase incorporated into a supported planar lipid bilayer. I. Binding of cytochrome c to cardiolipin/phosphatidylcholine membranes in the absence of oxidase. , 1996, Biophysical journal.

[81]  P. Schuck,et al.  Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules. , 1997, Annual review of biophysics and biomolecular structure.

[82]  J. Cann,et al.  Demonstration of an upper limit to the range of association rate constants amenable to study by biosensor technology based on surface plasmon resonance. , 1996, Analytical biochemistry.

[83]  R. J. Green,et al.  A surface plasmon resonance study of albumin adsorption to PEO-PPO-PEO triblock copolymers. , 1998, Journal of biomedical materials research.

[84]  L. W. Nichol.  Evaluation of equilibrium constants by affinity chromatography. , 1974, The Biochemical journal.

[85]  B. Liedberg,et al.  Principles of biosensing with an extended coupling matrix and surface plasmon resonance , 1993 .

[86]  D. Williams,et al.  Kinetic analysis of high-mobility-group proteins HMG-1 and HMG-I/Y binding to cholesterol-tagged DNA on a supported lipid monolayer. , 2000, Nucleic acids research.

[87]  I. Gustafson,et al.  Planar lipid bilayers on solid supports from liposomes--factors of importance for kinetics and stability. , 1997, Biochimica et biophysica acta.

[88]  T. Laue.  Sedimentation equilibrium as thermodynamic tool. , 1995, Methods in enzymology.

[89]  W. Sawyer,et al.  Characterisation of lipid‐protein interactions using a surface plasmon resonance biosensor , 1996, Biochemistry and molecular biology international.

[90]  Y. T. Sun,et al.  Calcium-dependent binding of rabbit C-reactive protein to supported lipid monolayers containing exposed phosphorylcholine group. , 1999, Biophysical journal.

[91]  R. Karlsson,et al.  Analysis of active antibody concentration. Separation of affinity and concentration parameters. , 1993, Journal of immunological methods.

[92]  C R MacKenzie,et al.  Quantitative Analysis of Bacterial Toxin Affinity and Specificity for Glycolipid Receptors by Surface Plasmon Resonance* , 1997, The Journal of Biological Chemistry.

[93]  Reassessment of the calibration constant for the IAsys biosensor. , 1999, Journal of chromatography. A.

[94]  M. Lackmann,et al.  Synergies between micropreparative high-performance liquid chromatography and an instrumental optical biosensor. , 1994, Journal of chromatography. A.

[95]  P. Talaga,et al.  Characterization of the carbohydrate binding specificity and kinetic parameters of lectins by using surface plasmon resonance. , 1999, Analytical biochemistry.

[96]  R J Leatherbarrow,et al.  Kinetics of protein-protein interactions at the surface of an optical biosensor. , 1995, Analytical biochemistry.

[97]  R. Karlsson.  Affinity analysis of non‐steady‐state data obtained under mass transport limited conditions using BIAcore technology , 1999, Journal of Molecular Recognition.

[98]  Bo Johnsson,et al.  Comparison of methods for immobilization to carboxymethyl dextran sensor surfaces by analysis of the specific activity of monoclonal antibodies , 1995, Journal of molecular recognition : JMR.

[99]  Ramsden,et al.  A Particle-Level Model of Irreversible Protein Adsorption with a Postadsorption Transition. , 1998, Journal of colloid and interface science.

[100]  H Roos,et al.  Thermodynamic analysis of protein interactions with biosensor technology , 1998, Journal of molecular recognition : JMR.

[101]  R. Colman,et al.  Kinetic analysis of the role of zinc in the interaction of domain 5 of high-molecular weight kininogen (HK) with heparin. , 2000, Biochemistry.

[102]  A. Minton,et al.  Analysis of mass transport-limited binding kinetics in evanescent wave biosensors. , 1996, Analytical biochemistry.

[103]  R. Nelson,et al.  BIA/MS: interfacing biomolecular interaction analysis with mass spectrometry. , 1997, Analytical biochemistry.

[104]  D. Winzor,et al.  Interpretation of deviations from pseudo-first-order kinetic behavior in the characterization of ligand binding by biosensor technology. , 1996, Analytical biochemistry.

[105]  D. Winzor,et al.  Potential of biosensor technology for the characterization of interactions by quantitative affinity chromatography. , 1998, Journal of chromatography. B, Biomedical sciences and applications.

[106]  A. Minton,et al.  Adsorption of globular proteins on locally planar surfaces: models for the effect of excluded surface area and aggregation of adsorbed protein on adsorption equilibria. , 1996, Biophysical journal.

[107]  J. Hubbell,et al.  Poly(l-lysine)-g-Poly(ethylene glycol) Layers on Metal Oxide Surfaces: Attachment Mechanism and Effects of Polymer Architecture on Resistance to Protein Adsorption† , 2000 .

[108]  M L Yarmush,et al.  An analysis of transport resistances in the operation of BIAcore; implications for kinetic studies of biospecific interactions. , 1996, Molecular immunology.

[109]  N. Athanassopoulou,et al.  Cholera Toxin and GMI: A Model membrane study with IAsys , 1999 .

[110]  L. Christensen.  Theoretical analysis of protein concentration determination using biosensor technology under conditions of partial mass transport limitation. , 1997, Analytical biochemistry.

[111]  S Neidle,et al.  Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA). , 1995, Nucleic acids research.

[112]  K. Pavey,et al.  SPR analysis of the total reduction of protein adsorption to surfaces coated with mixtures of long- and short-chain polyethylene oxide block copolymers. , 1999, Biomaterials.

[113]  Richard O'Kennedy,et al.  Transduction platforms and biointerfacial design of biosensors for 'real-time' biomolecular interaction analysis , 1999 .

[114]  I. Chaiken,et al.  Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration. , 1995, Analytical biochemistry.

[115]  Ramsden,et al.  Kinetics of Human and Bovine Serum Albumin Adsorption at Silica-Titania Surfaces , 1997, Journal of colloid and interface science.

[116]  Z. Salamon,et al.  Plasmon resonance spectroscopy: probing molecular interactions within membranes. , 1999, Trends in biochemical sciences.

[117]  P. Schuck,et al.  Kinetics of ligand binding to receptor immobilized in a polymer matrix, as detected with an evanescent wave biosensor. I. A computer simulation of the influence of mass transport. , 1996, Biophysical journal.

[118]  J. Lidholm,et al.  BIACORE analysis of histidine-tagged proteins using a chelating NTA sensor chip. , 1997, Analytical biochemistry.

[119]  M. V. Van Regenmortel,et al.  Concentration measurement of unpurified proteins using biosensor technology under conditions of partial mass transport limitation. , 1997, Analytical biochemistry.

[120]  S. Blondelle,et al.  Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity. , 1999, Biochimica et biophysica acta.

[121]  F. C. Andrews.  A simple approach to the equilibrium statistical mechanics of two‐dimensional fluids , 1976 .

[122]  J Witz,et al.  Thermodynamic analysis of antigen-antibody binding using biosensor measurements at different temperatures. , 1997, Analytical biochemistry.

[123]  P. Lowe,et al.  New approaches for the analysis of molecular recognition using the IAsys evanescent wave biosensor , 1998, Journal of molecular recognition : JMR.

[124]  S. Stankowski.  Large-ligand adsorption to membranes. II: Disk-like ligands and shape-dependence at low saturation , 1983 .

[125]  G. Hausdorf,et al.  Binding kinetics of an antibody against HIV p24 core protein measured with real-time biomolecular interaction analysis suggest a slow conformational change in antigen p24. , 1996, Journal of immunological methods.

[126]  Ramsden,et al.  Kinetic evidence for protein clustering at a surface. , 1994, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[127]  J. Davies,et al.  Surface Analytical Techniques for Probing Biomaterial Processes , 1996 .

[128]  G. Tarjus,et al.  Generalized random sequential adsorption , 1990 .

[129]  Ramsden,et al.  Concentration scaling of protein deposition kinetics. , 1993, Physical review letters.

[130]  C. Lowe,et al.  The Resonant Mirror: A Versatile Tool for the Study of Biomolecular Interactions , 1994 .

[131]  W. Lukosz,et al.  Principles and sensitivities of integrated optical and surface plasmon sensors for direct affinity sensing and immunosensing , 1991 .

[132]  Talbot,et al.  Kinetics of random sequential adsorption. , 1989, Physical review letters.

[133]  I. Langmuir.  THE ADSORPTION OF GASES ON PLANE SURFACES OF GLASS, MICA AND PLATINUM. , 1918 .

[134]  J. Ramsden,et al.  Kinetics of the interaction between DNA and the type IC restriction enzyme EcoR124II. , 1996, Biochemistry.

[135]  I. Brooks,et al.  Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods. , 1993, Analytical biochemistry.

[136]  D G Myszka,et al.  Advances in surface plasmon resonance biosensor analysis. , 2000, Current opinion in biotechnology.

[137]  M. Doyle,et al.  Interpreting kinetic rate constants from optical biosensor data recorded on a decaying surface. , 1998, Analytical biochemistry.

[138]  T. Nishikiori,et al.  Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin. , 1999, The Biochemical journal.

[139]  M. Umeda,et al.  Lysenin, a Novel Sphingomyelin-specific Binding Protein* , 1998, The Journal of Biological Chemistry.

[140]  J. Talbot.  Molecular thermodynamics of binary mixture adsorption: A scaled particle theory approach , 1997 .

[141]  I Karube,et al.  Application of peptide nucleic acid to the direct detection of deoxyribonucleic acid amplified by polymerase chain reaction. , 1999, Biosensors & bioelectronics.

[142]  Hitoshi Muguruma,et al.  A Plasma-Polymerized Film for Surface Plasmon Resonance Immunosensing , 1997 .

[143]  H Roos,et al.  Biosensor analysis of the interaction between immobilized human serum albumin and drug compounds for prediction of human serum albumin binding levels. , 2000, Journal of medicinal chemistry.

[144]  A. Kortt,et al.  Identification and minimization of nonideal binding effects in BIAcore analysis: ferritin/anti-ferritin Fab' interaction as a model system. , 1997, Analytical biochemistry.

[145]  P. Iliades,et al.  Nonspecific amine immobilization of ligand can Be a potential source of error in BIAcore binding experiments and may reduce binding affinities. , 1997, Analytical biochemistry.

[146]  K. Shakesheff,et al.  Dynamic Surface Events Measured by Simultaneous Probe Microscopy and Surface Plasmon Detection , 1996 .

[147]  R. Fisher,et al.  BIAcore for macromolecular interaction. , 1998, Current opinion in biotechnology.

[148]  D. Winzor,et al.  Theoretical and experimental considerations of the pseudo-first-order approximation in conventional kinetic analysis of IAsys biosensor data. , 1997, Analytical biochemistry.

[149]  A. Archakov,et al.  Immobilization of proteins to lipid bilayers. , 1996, Biosensors & bioelectronics.