Simultaneous wavefront and 3D tomographic reconstructions for phase imaging using Hartmann sensor

X-ray absorption imaging is used in the medical field since a long time, but recent advance in phase-contrast imaging made it feasible in a clinical setup. X-ray Phase-contrast imaging technique using a Hartmann sensor allows extracting the absorption and phase information in a single acquisition, allowing to extract a phase-shift information with a minimal exposition and deposited dose. An iterative wavefront reconstruction (IR-WF) algorithm is necessary to extract the phase and absorption values from an acquired image. Our method consists of merging the wavefront reconstruction with a computed tomographic iterative reconstruction (IR-CT) to ensure that all images converge to the same result, improving the final 3D volume.

[1]  P. Zeitoun,et al.  High-Sensitivity X-ray Phase Imaging System Based on a Hartmann Wavefront Sensor , 2021, Condensed Matter.

[2]  Xavier Levecq,et al.  EUV and Hard X-ray Hartmann Wavefront Sensing for Optical Metrology, Alignment and Phase Imaging , 2021, Sensors.

[3]  Dong Zeng,et al.  Regularization strategies in statistical image reconstruction of low‐dose x‐ray CT: A review , 2018, Medical physics.

[4]  John M. Boone,et al.  Monte Carlo evaluation of glandular dose in cone-beam X-ray computed tomography dedicated to the breast: Homogeneous and heterogeneous breast models. , 2018, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

[5]  S Pacilè,et al.  Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow. , 2015, Biomedical optics express.

[6]  P. C. Diemoz,et al.  Low-dose phase contrast tomography with conventional x-ray sources. , 2014, Medical physics.

[7]  J. Fessler,et al.  Modelling the physics in the iterative reconstruction for transmission computed tomography , 2013, Physics in medicine and biology.

[8]  Zhou Yu,et al.  Recent Advances in CT Image Reconstruction , 2013, Current Radiology Reports.

[9]  Paola Coan,et al.  X-ray phase-contrast imaging: from pre-clinical applications towards clinics , 2013, Physics in medicine and biology.

[10]  E. Somersalo,et al.  Statistical inversion for medical x-ray tomography with few radiographs: I. General theory. , 2003, Physics in medicine and biology.

[11]  W. Southwell Wave-front estimation from wave-front slope measurements , 1980 .

[12]  Avinash C. Kak,et al.  7. Algebraic Reconstruction Algorithms , 2001 .

[13]  F. Natterer The Mathematics of Computerized Tomography , 1986 .

[14]  Algebraic Reconstruction Algorithms , 2022 .