A possible unifying principle for mechanosensation

[1]  C. Kung,et al.  Heterologously expressed fungal transient receptor potential channels retain mechanosensitivity in vitro and osmotic response in vivo , 2005, European Biophysics Journal.

[2]  M. Lazdunski,et al.  Lysophosphatidic Acid-operated K+ Channels* , 2005, Journal of Biological Chemistry.

[3]  A. Kurosky,et al.  TRPC1 forms the stretch-activated cation channel in vertebrate cells , 2005, Nature Cell Biology.

[4]  M. Lazdunski,et al.  A phospholipid sensor controls mechanogating of the K+ channel TREK‐1 , 2005, The EMBO journal.

[5]  Cori Bargmann,et al.  Specific Polyunsaturated Fatty Acids Drive TRPV-Dependent Sensory Signaling In Vivo , 2004, Cell.

[6]  Heidi L. Rehm,et al.  TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells , 2004, Nature.

[7]  M. Chalfie,et al.  Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons , 2004, Neuron.

[8]  W. Schafer,et al.  The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation , 2004, Nature Neuroscience.

[9]  M. Chalfie,et al.  MEC-2 Is Recruited to the Putative Mechanosensory Complex in C. elegans Touch Receptor Neurons through Its Stomatin-like Domain , 2004, Current Biology.

[10]  G. Richardson,et al.  Hair Cells Require Phosphatidylinositol 4,5-Bisphosphate for Mechanical Transduction and Adaptation , 2004, Neuron.

[11]  Zhefeng Gong,et al.  Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in Drosophila , 2004, The Journal of Neuroscience.

[12]  V. Flockerzi,et al.  Ca2+-selective Transient Receptor Potential V Channel Architecture and Function Require a Specific Ankyrin Repeat* , 2004, Journal of Biological Chemistry.

[13]  Bernd Nilius,et al.  The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels , 2004, Nature.

[14]  F. Sachs,et al.  Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers , 2004, Nature.

[15]  E. M. Adler,et al.  Focus Issue: Tuning in to the Ion Channel , 2004, Science's STKE.

[16]  Stephan C. Schuster,et al.  Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells , 2004, Nature.

[17]  Peter G. Gillespie,et al.  Cadherin 23 is a component of the tip link in hair-cell stereocilia , 2004, Nature.

[18]  D. Corey,et al.  Hearing: Tightrope act , 2004, Nature.

[19]  A. Patapoutian,et al.  Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin , 2004, Neuron.

[20]  Jonathon Howard,et al.  Hypothesis: A helix of ankyrin repeats of the NOMPC-TRP ion channel is the gating spring of mechanoreceptors , 2004, Current Biology.

[21]  Sergei Sukharev,et al.  Mechanosensitive Channels: Multiplicity of Families and Gating Paradigms , 2004, Science's STKE.

[22]  D. McKemy,et al.  Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 , 2004, Nature.

[23]  H. Watanabe,et al.  Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4 , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[24]  David E. Clapham,et al.  TRP channels as cellular sensors , 2003, Nature.

[25]  David M Tobin,et al.  Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Rob Phillips,et al.  Analytic models for mechanotransduction: Gating a mechanosensitive channel , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[27]  K. Schulten,et al.  Gating of MscL studied by steered molecular dynamics. , 2003, Biophysical journal.

[28]  D. Corey,et al.  New TRP Channels in Hearing and Mechanosensation , 2003, Neuron.

[29]  B. Nilius,et al.  Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels , 2003, Nature.

[30]  R. O'neil,et al.  Temperature-modulated Diversity of TRPV4 Channel Gating , 2003, Journal of Biological Chemistry.

[31]  Rainer W Friedrich,et al.  NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction , 2003, Science.

[32]  Maurice J. Kernan,et al.  A TRPV family ion channel required for hearing in Drosophila , 2003, Nature.

[33]  K. Kodaira,et al.  Impaired Pressure Sensation in Mice Lacking TRPV4* , 2003, Journal of Biological Chemistry.

[34]  J. A. Maurer,et al.  Generation and Evaluation of a Large Mutational Library from the Escherichia coli Mechanosensitive Channel of Large Conductance, MscL , 2003, Journal of Biological Chemistry.

[35]  C. Kung,et al.  The transient receptor potential channel on the yeast vacuole is mechanosensitive , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Gilles Laurent,et al.  painless, a Drosophila Gene Essential for Nociception , 2003, Cell.

[37]  Peter McIntyre,et al.  ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures , 2003, Cell.

[38]  P. Blount.  Molecular Mechanisms of Mechanosensation Big Lessons from Small Cells , 2003, Neuron.

[39]  Miriam B Goodman,et al.  Transducing touch in Caenorhabditis elegans. , 2003, Annual review of physiology.

[40]  Martin Chalfie,et al.  The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel , 2002, Nature.

[41]  Pavel Strop,et al.  Crystal Structure of Escherichia coli MscS, a Voltage-Modulated and Mechanosensitive Channel , 2002, Science.

[42]  T. Vogt,et al.  Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[43]  M. Caterina,et al.  Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1 , 2002, Nature Neuroscience.

[44]  Boris Martinac,et al.  Open channel structure of MscL and the gating mechanism of mechanosensitive channels , 2002, Nature.

[45]  Cori Bargmann,et al.  Combinatorial Expression of TRPV Channel Proteins Defines Their Sensory Functions and Subcellular Localization in C. elegans Neurons , 2002, Neuron.

[46]  Youxing Jiang,et al.  The open pore conformation of potassium channels , 2002, Nature.

[47]  C. Montell,et al.  The TRP Channels, a Remarkably Functional Family , 2002, Cell.

[48]  M. Chalfie,et al.  MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation , 2002, Nature.

[49]  M. Cyert,et al.  Internal Ca2+ release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue , 2002, The Journal of cell biology.

[50]  E. Honoré,et al.  Anesthetic-sensitive 2P Domain K+ Channels , 2001, Anesthesiology.

[51]  A. Patel,et al.  Lipid and mechano-gated 2P domain K(+) channels. , 2001, Current opinion in cell biology.

[52]  C. Kung,et al.  A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca2+-permeable channel in the yeast vacuolar membrane , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[53]  S. Sukharev,et al.  Dipole potentials indicate restructuring of the membrane interface induced by gadolinium and beryllium ions. , 2001, Biophysical journal.

[54]  O. Hamill,et al.  Molecular basis of mechanotransduction in living cells. , 2001, Physiological reviews.

[55]  H. Robert Guy,et al.  The gating mechanism of the large mechanosensitive channel MscL , 2001, Nature.

[56]  A. Hudspeth,et al.  Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor , 2000, Cell.

[57]  G. Schultz,et al.  OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity , 2000, Nature Cell Biology.

[58]  E. Lindahl,et al.  Spatial and energetic-entropic decomposition of surface tension in lipid bilayers from molecular dynamics simulations , 2000 .

[59]  F. Sachs,et al.  Identification of a Peptide Toxin from Grammostola spatulata Spider Venom That Blocks Cation-Selective Stretch-Activated Channels , 2000, The Journal of general physiology.

[60]  M. Lazdunski,et al.  Lysophospholipids Open the Two-pore Domain Mechano-gated K+ Channels TREK-1 and TRAAK* , 2000, The Journal of Biological Chemistry.

[61]  C. Zuker,et al.  A Drosophila mechanosensory transduction channel. , 2000, Science.

[62]  O. Hamill,et al.  Mechanically gated channel activity in cytoskeleton‐deficient plasma membrane blebs and vesicles from Xenopus oocytes , 2000, The Journal of physiology.

[63]  O. Hamill,et al.  On the discrepancy between whole‐cell and membrane patch mechanosensitivity in Xenopus oocytes , 2000, The Journal of physiology.

[64]  Paul W. Sternberg,et al.  A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans , 1999, Nature.

[65]  R. Cantor,et al.  The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria. , 1999, Chemistry and physics of lipids.

[66]  Frederick Sachs,et al.  Energetic and Spatial Parameters for Gating of the Bacterial Large Conductance Mechanosensitive Channel, MscL , 1999, The Journal of general physiology.

[67]  I. Booth,et al.  Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity , 1999, The EMBO journal.

[68]  D C Rees,et al.  Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel. , 1998, Science.

[69]  R. Cantor,et al.  The lateral pressure profile in membranes: a physical mechanism of general anesthesia. , 1998, Biochemistry.

[70]  C. Kung,et al.  One face of a transmembrane helix is crucial in mechanosensitive channel gating. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[71]  M. Lazdunski,et al.  A mammalian two pore domain mechano‐gated S‐like K+ channel , 1998, The EMBO journal.

[72]  C. Montell.  TRP trapped in fly signaling web , 1998, Current Opinion in Neurobiology.

[73]  Cori Bargmann,et al.  OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans , 1997, The Journal of Neuroscience.

[74]  D. Julius,et al.  The capsaicin receptor: a heat-activated ion channel in the pain pathway , 1997, Nature.

[75]  Emiko Suzuki,et al.  A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade , 1997, Nature.

[76]  O. Andersen,et al.  Lipid bilayer electrostatic energy, curvature stress, and assembly of gramicidin channels. , 1997, Biochemistry.

[77]  R. Cantor.  Lateral Pressures in Cell Membranes: A Mechanism for Modulation of Protein Function , 1997 .

[78]  H. Guy,et al.  Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coli. , 1996, The EMBO journal.

[79]  D. W. McBride,et al.  The pharmacology of mechanogated membrane ion channels. , 1996, Pharmacological reviews.

[80]  Patricia A. Gabow,et al.  PKD2, a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein , 1996, Science.

[81]  Boris Martinac,et al.  A large-conductance mechanosensitive channel in E. coli encoded by mscL alone , 1994, Nature.

[82]  C. Kung,et al.  Functional Reconstitution as an Assay for Biochemical Isolation of Channel Proteins: Application to the Molecular Identification of a Bacterial Mechanosensitive Channel , 1994 .

[83]  C Kung,et al.  Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution. , 1993, Biophysical journal.

[84]  M. Zoratti,et al.  Gadolinium ion inhibits loss of metabolites induced by osmotic shock and large stretch-activated channels in bacteria. , 1992, European journal of biochemistry.

[85]  C. Morris,et al.  Failure to elicit neuronal macroscopic mechanosensitive currents anticipated by single-channel studies. , 1991, Science.

[86]  Boris Martinac,et al.  Mechanosensitive ion channels of E. coli activated by amphipaths , 1990, Nature.

[87]  C. Morris.  Mechanosensitive ion channels , 1990, The Journal of Membrane Biology.

[88]  C Kung,et al.  Modified reconstitution method used in patch-clamp studies of Escherichia coli ion channels. , 1989, Biophysical journal.

[89]  F. Sachs,et al.  Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions. , 1989, Science.

[90]  C Kung,et al.  Pressure-sensitive ion channel in Escherichia coli. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[91]  F Sachs,et al.  Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle. , 1984, The Journal of physiology.

[92]  W. Pak,et al.  Induction of photoreceptor voltage noise in the dark in Drosophila mutant , 1975, Nature.

[93]  M. Sheetz,et al.  Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[94]  A. Kleinzeller,et al.  Current Topics in Membranes and Transport , 1970 .

[95]  R. Britten,et al.  The amino acid pool in Escherichia coli. , 1962, Bacteriological reviews.

[96]  M. Chalfie,et al.  The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals , 2005, Nature Neuroscience.

[97]  Martin Chalfie,et al.  Genetics of sensory mechanotransduction. , 2002, Annual review of genetics.

[98]  Boris Martinac,et al.  Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating , 2002, Nature Structural Biology.

[99]  C Kung,et al.  Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities. , 1997, Annual review of physiology.

[100]  D. Houlihan,et al.  Advances in Comparative and Environmental Physiology , 1991, Advances in Comparative and Environmental Physiology.

[101]  P. A. Anderson,et al.  Evolution of the First Nervous Systems , 1989, NATO ASI Series.

[102]  Aristotle,et al.  Aristotle's On the soul (De anima) , 1981 .