Mobile eHealth solution (ePRO)

• Study server – manages the connection between mobile and web applications and the TSS • Study database – stores all information about studies, patients, randomization etc. • Web application – enables filling in PROMs by patients and CROMs by GPs (investigators) • Mobile application – enables filling in PROMs by the patients using smartphones or other devices • Middleware ESB which serves as a connection, authorization and security layer between TSS and the rest of the infrastructure