Clinicopathologic review of 19 patients with systemic candidiasis with skin lesions

Background  A diagnosis of systemic candidiasis is often delayed or missed owing to the absence of sensitive, specific, and timely diagnostic tools. Skin lesions are not common, but they can help to rapidly establish a diagnosis. We report on a 14‐year experience of systemic candidiasis with skin lesions in our institution. We report the prevalence, clinical findings, histologic findings, etiologic Candida species, underlying conditions, treatment modalities, and outcomes of the cases and compare them with the previous reports.

[1]  A. Ellepola,et al.  Laboratory diagnosis of invasive candidiasis. , 2005, Journal of microbiology.

[2]  B. Mogilner,et al.  Systemic candidal infections associated with use of peripheral venous catheters in neonates: a 9-year experience. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  T. C. Jones Precursors for wide band gap II–VI semiconductors , 1990 .

[4]  T. Ray Systemic candidiasis. , 1989, Dermatologic clinics.

[5]  R. Silverman,et al.  Systemic candidiasis: cutaneous manifestations in low birth weight infants. , 1988, Pediatrics.

[6]  J. Miro,et al.  Systemic Candidiasis in Heroin Abusers Cutaneous Findings , 1987, International journal of dermatology.

[7]  T. Sorrell,et al.  Disseminated candidiasis: evidence of a distinctive syndrome in heroin abusers. , 1983, British medical journal.

[8]  J. Miller,et al.  Cutaneous lesions in disseminated candidiasis mimicking ecthyma gangrenosum. , 1981, The American journal of medicine.

[9]  D. Silvers,et al.  Cutaneous manifestations of disseminated candidiasis. , 1980, Journal of the American Academy of Dermatology.

[10]  J. Wingard,et al.  Candida tropicalis: a major pathogen in immunocompromised patients. , 1979, Annals of internal medicine.

[11]  T. File,et al.  Necrotic skin lesions associated with disseminated candidiasis. , 1979, Archives of dermatology.

[12]  R. Silver,et al.  Fever, rash, and muscle tenderness. A distinctive clinical presentation of disseminated candidiasis. , 1978, Archives of internal medicine.

[13]  G. Bodey,et al.  Skin lesions associated with disseminated candidiasis. , 1974, JAMA.

[14]  J. Seabury,et al.  A cutaneous manifestation of systemic candidiasis. , 1973, Annals of internal medicine.

[15]  G. Bodey Fungal infections complicating acute leukemia. , 1966, Journal of chronic diseases.