A combination of genetics and microbiota influences the severity of the obesity phenotype in diet-induced obesity

[1]  E. Feingold,et al.  Gene Expression and Cardiometabolic Phenotypes of Vitamin D-Deficient Overweight and Obese Black Children , 2019, Nutrients.

[2]  Tiziana Caputo.  Early modification of the adipose tissue linking obesity and metaflammation , 2019 .

[3]  C. Kim,et al.  Chromosomal microarray analysis in the genetic evaluation of 279 patients with syndromic obesity , 2018, Molecular Cytogenetics.

[4]  A. Bleich,et al.  Loss of CD14 leads to disturbed epithelial-B cell crosstalk and impairment of the intestinal barrier after E. coli Nissle monoassociation , 2018, Scientific Reports.

[5]  T. Inagaki.  Regulations of Adipocyte Phenotype and Obesity by IRX3. Positive or Negative? , 2017, EBioMedicine.

[6]  D. Pieper,et al.  Uncovering the trimethylamine-producing bacteria of the human gut microbiota , 2017, Microbiome.

[7]  H. Daniel,et al.  Dietary fat and gut microbiota interactions determine diet-induced obesity in mice , 2016, Molecular metabolism.

[8]  D. Fontaine,et al.  Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium , 2015, Diabetes.

[9]  E. Manukhina,et al.  C57BL/6N Mice Are More Resistant to Ehrlich Ascites Tumors Than C57BL/6J Mice: The Role of Macrophage Nitric Oxide , 2015, Medical science monitor basic research.

[10]  D. Colin,et al.  Microbiota depletion promotes browning of white adipose tissue and reduces obesity , 2015, Nature Medicine.

[11]  H. Hakonarson,et al.  Pathway-Based Genome-Wide Association Studies for Plasma Triglycerides in Obese Females and Normal-Weight Controls , 2015, PloS one.

[12]  K. Svenson,et al.  Diet dominates host genotype in shaping the murine gut microbiota. , 2015, Cell host & microbe.

[13]  Tamara S. Roman,et al.  New genetic loci link adipose and insulin biology to body fat distribution , 2014, Nature.

[14]  A. Yoshiki,et al.  Development of SNP markers for C57BL/6N-derived mouse inbred strains , 2014, Experimental animals.

[15]  B. Rohrer,et al.  A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization. , 2014, Experimental eye research.

[16]  Angela C. Poole,et al.  Human Genetics Shape the Gut Microbiome , 2014, Cell.

[17]  M. McCarthy,et al.  Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications , 2014, Diabetes.

[18]  I. Wilson,et al.  Age and Microenvironment Outweigh Genetic Influence on the Zucker Rat Microbiome , 2014, PloS one.

[19]  M. Stumvoll,et al.  Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains. , 2014, Physiological genomics.

[20]  N. Cox,et al.  Obesity-associated variants within FTO form long-range functional connections with IRX3 , 2014, Nature.

[21]  Jaspinder Kaur.  A Comprehensive Review on Metabolic Syndrome , 2014, Cardiology research and practice.

[22]  D. Wedekind,et al.  Norovirus Triggered Microbiota-driven Mucosal Inflammation in Interleukin 10-deficient Mice , 2014, Inflammatory bowel diseases.

[23]  James R. Cole,et al.  Ribosomal Database Project: data and tools for high throughput rRNA analysis , 2013, Nucleic Acids Res..

[24]  A. Vercesi,et al.  A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities. , 2013, Free radical biology & medicine.

[25]  J. Clemente,et al.  Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice , 2013, Science.

[26]  R. Tian,et al.  Substrain specific response to cardiac pressure overload in C57BL/6 mice. , 2013, American journal of physiology. Heart and circulatory physiology.

[27]  Henrik Westerberg,et al.  A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains , 2013, Genome Biology.

[28]  Liping Zhao,et al.  Structural modulation of gut microbiota in life-long calorie-restricted mice , 2013, Nature Communications.

[29]  M. Levings,et al.  Immune Regulation in Obesity-Associated Adipose Inflammation , 2013, The Journal of Immunology.

[30]  M. Olivier,et al.  QTL-based association analyses reveal novel genes influencing pleiotropy of Metabolic Syndrome (MetS) , 2013, Obesity.

[31]  M. Marco,et al.  The intestinal microbiota in aged mice is modulated by dietary resistant starch and correlated with improvements in host responses. , 2013, FEMS microbiology ecology.

[32]  Eleazar Eskin,et al.  Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. , 2013, Cell metabolism.

[33]  S. Woods,et al.  Overview of Animal Models of Obesity , 2012, Current protocols in pharmacology.

[34]  Olle Korsgren,et al.  A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets. , 2012, Cell metabolism.

[35]  Robert W. Williams,et al.  Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits , 2012, PloS one.

[36]  R. Goyal,et al.  Evaluation of TNF-α and IL-6 Levels in Obese and Non-obese Diabetics: Pre- and Postinsulin Effects , 2012, North American journal of medical sciences.

[37]  R. Bergman,et al.  Simultaneous measurement of insulin sensitivity, insulin secretion and the disposition index in conscious unhandled mice , 2012, Obesity.

[38]  C. Brayton,et al.  Immunological Variation Between Inbred Laboratory Mouse Strains , 2012, Veterinary pathology.

[39]  K. Waymire,et al.  The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2 , 2012, G3: Genes, Genomes, Genetics.

[40]  F. Pazos,et al.  Genetic polymorphisms among C57BL/6 mouse inbred strains , 2011, Transgenic Research.

[41]  L. Thibault,et al.  High-fat diet-induced obesity in animal models , 2010, Nutrition Research Reviews.

[42]  Fei Wang,et al.  The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice , 2010, PloS one.

[43]  Min Zhang,et al.  Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors , 2010, Proceedings of the National Academy of Sciences.

[44]  E. Leiter,et al.  Diet‐induced Obesity in Two C57BL/6 Substrains With Intact or Mutant Nicotinamide Nucleotide Transhydrogenase (Nnt) Gene , 2010, Obesity.

[45]  P. Arner,et al.  Mapping of the fibroblast growth factors in human white adipose tissue. , 2010, The Journal of clinical endocrinology and metabolism.

[46]  A. Schwiertz,et al.  Microbiota and SCFA in Lean and Overweight Healthy Subjects , 2010, Obesity.

[47]  G. Morahan,et al.  The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance. , 2010, Endocrinology.

[48]  Jens C. Brüning,et al.  Inactivation of the Fto gene protects from obesity , 2009, Nature.

[49]  A. Yoshiki,et al.  Genetic differences among C57BL/6 substrains. , 2009, Experimental animals.

[50]  B. Roe,et al.  A core gut microbiome in obese and lean twins , 2008, Nature.

[51]  Michael S Fanselow,et al.  Please Scroll down for Article Journal of Neurogenetics Behavioral Differences among C57bl/6 Substrains: Implications for Transgenic and Knockout Studies Behavioral Differences among C57bl/6 Substrains: Implications for Transgenic and Knockout Studies , 2022 .

[52]  Beverley Balkau,et al.  Variation in FTO contributes to childhood obesity and severe adult obesity , 2007, Nature Genetics.

[53]  James Strait,et al.  Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits , 2007, PLoS genetics.

[54]  Jeffrey I. Gordon,et al.  Mechanisms underlying the resistance to diet-induced obesity in germ-free mice , 2007, Proceedings of the National Academy of Sciences.

[55]  E. Mardis,et al.  An obesity-associated gut microbiome with increased capacity for energy harvest , 2006, Nature.

[56]  F. Ashcroft,et al.  Deletion of Nicotinamide Nucleotide Transhydrogenase , 2006, Diabetes.

[57]  F. Bäckhed,et al.  Obesity alters gut microbial ecology. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[58]  F. Ashcroft,et al.  A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice , 2005, Diabetologia.

[59]  M. Desai,et al.  Obesity is associated with macrophage accumulation in adipose tissue. , 2003, The Journal of clinical investigation.

[60]  C. Farley,et al.  Fat intake affects adiposity, comorbidity factors, and energy metabolism of sprague-dawley rats. , 2002, Obesity research.

[61]  A. Astrup,et al.  Obesity : Preventing and managing the global epidemic , 2000 .