Regioselective N-alkylation of some imidazole-containing heterocycles and their in vitro anticancer evaluation
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A. Karabay | H. Göker | Çiğdem Karaaslan | A. Koç | M. Alp | Fatima Doganc
[1] H. Göker,et al. Regioselective N–alkylation of 2– (3,4–dimethoxyphenyl)imidazo[4,5–b] and [4,5–c]pyridine oxide derivatives : Synthesis and structure elucidation by NMR , 2019 .
[2] T. Hökelek,et al. Crystal structure and Hirshfeld surface analysis of 4-allyl-6-bromo-2-(4-chlorophenyl)-4H-imidazo[4,5-b]pyridine , 2019, Acta crystallographica. Section E, Crystallographic communications.
[3] P. Stańczak,et al. Solvent-Controlled, Site-Selective N-Alkylation Reactions of Azolo-Fused Ring Heterocycles at N1-, N2-, and N3-Positions, Including Pyrazolo[3,4- d]pyrimidines, Purines, [1,2,3]Triazolo[4,5]pyridines, and Related Deaza-Compounds. , 2018, The Journal of organic chemistry.
[4] K. Gobis,et al. Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives , 2017, Molecules.
[5] Jianxin Yu,et al. Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal-epithelial transition factor (c-Met) protein kinase. , 2016, Bioorganic & medicinal chemistry.
[6] H. Goker,et al. Separation and identification of the mixture of 2‐(3,4‐dimethoxyphenyl)‐1‐n‐propyl or (4‐chlorobenzyl)‐5 and (6)‐1H‐benzimidazolecarbonitriles , 2016, Magnetic resonance in chemistry : MRC.
[7] Carla I. Nieto,et al. An experimental and theoretical NMR study of NH-benzimidazoles in solution and in the solid state: proton transfer and tautomerism , 2014, Beilstein journal of organic chemistry.
[8] J. García‐Ruiz,et al. Stereospecific alkylation of substituted adenines by the Mitsunobu coupling reaction under microwave-assisted conditions , 2014 .
[9] S. Luis,et al. Synthesis and Crystal Structure of 6-Bromo-2-(furan-2-yl)-3-(prop-2-ynyl)-3H-imidazo[4,5-b]pyridine , 2013 .
[10] D. Mortensen,et al. Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors. , 2011, Bioorganic & medicinal chemistry letters.
[11] R. Butcher,et al. 3-[2-(6-Bromo-2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)ethyl]-1,3-oxazolidin-2-one , 2011, Acta crystallographica. Section E, Structure reports online.
[12] Nahid M. Yazdani,et al. Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOS , 2010, Journal of medicinal chemistry.
[13] S. Ng,,et al. 4-Allyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine monohydrate , 2010, Acta crystallographica. Section E, Structure reports online.
[14] S. Ng,,et al. 3-Benzyl-6-bromo-2-(2-furyl)-3H-imidazo[4,5-b]pyridine , 2010, Acta crystallographica. Section E, Structure reports online.
[15] S. Radix,et al. Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter. , 2010, European journal of medicinal chemistry.
[16] Seik Weng Ng,et al. 4-Benzyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine , 2010, Acta crystallographica. Section E, Structure reports online.
[17] S. Ng,,et al. 4-Benzyl-6-bromo-2-(4-methoxyphenyl)-4H-imidazo[4,5-b]pyridine monohydrate , 2010, Acta crystallographica. Section E, Structure reports online.
[18] W. Parker. Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer. , 2009, Chemical reviews.
[19] J. Pilmé,et al. Regioselective N-alkylation of imidazo[4,5-b]pyridine-4-oxide derivatives: an experimental and DFT study , 2009 .
[20] William A. Lee,et al. Substituted imidazopyridines as potent inhibitors of HCV replication , 2009, Journal of Hepatology.
[21] E. De Clercq,et al. Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors. , 2006, Bioorganic & medicinal chemistry letters.
[22] N. Katagiri,et al. Mitsunobu Reactions for the Synthesis of Carbocyclic Analogues of Nucleosides: Examination of the Regioselectivity1 , 1993 .
[23] F. Janssens,et al. New antihistaminic N-heterocyclic 4-piperidinamines. 3. Synthesis and antihistaminic activity of N-(4-piperidinyl)-3H-imidazo[4,5-b]pyridin-2-amines. , 1985, Journal of medicinal chemistry.
[24] T. Mosmann. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.
[25] B. Pullman,et al. Electronic Aspects of Purine Tautomerism , 1971 .