论文信息 - Structure-activity relationship studies of chemical mutagens and carcinogens: mechanistic investigations and prediction approaches.

Structure-activity relationship studies of chemical mutagens and carcinogens: mechanistic investigations and prediction approaches.

2.3.3. Carcinogenicity of N-Nitrosamines 1781 2.4. Quinolines 1781 2.5. Triazenes 1782 2.6. Polycyclic Aromatic Hydrocarbons 1783 2.6.1. QSARs for the Carcinogenicity of PAHs 1783 2.6.2. QSARs for the Genotoxicity of PAHs 1784 2.7. Halogenated Aliphatics 1784 2.8. Direct-Acting Compounds 1785 2.8.1. Mutagenicity of Platinum Amines 1785 2.8.2. Mutagenicity of Lactones 1785 2.8.3. Mutagenicity of Epoxides 1786 3. Nongenotoxic or Epigenetic Carcinogens 1786 4. QSAR Models For Noncongeneric Chemicals 1788 4.1. Statistically Based Approaches for Noncongeneric Datasets 1789

R. Benigni

[1] G. Suchowsky,et al. BIOLOGICAL ACTIVITY AND CHEMICAL STRUCTURE. , 1963, Nihon Naibunpi Gakkai zasshi.

[2] A. J. Stuper,et al. Computer assisted studies of chemical structure and biological function , 1979 .

[3] Rainer Franke,et al. Theoretical drug design methods , 1984 .

[4] R. Harvey. Polycyclic hydrocarbons and carcinogenesis , 1985 .

[5] F. Guengerich. Mammalian cytochromes P-450 , 1987 .

[6] Nancy N. Ragsdale,et al. Carcinogenicity and pesticides. Principles, issues, and relationships. , 1989 .

[7] Yin-tak Woo,et al. Chemical induction of cancer : modulation and combination effects : an inventory of the many factors which influence carcinogenesis , 1995 .

[8] Yin-tak Woo,et al. Chemical Induction of Cancer , 1995, Birkhäuser Boston.

[9] Jeffrey P. Jones,et al. Designing safer chemicals: predicting the rates of metabolism of halogenated alkanes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[10] Stephen C. DeVito,et al. Designing safer chemicals : green chemistry for pollution prevention : developed from a symposium sponsored by the Division of Environmenal Chemistry, Inc. , 1996 .

[11] Hugo Kubinyi,et al. 3D QSAR in drug design : theory, methods and applications , 2000 .

[12] Romualdo Benigni,et al. Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens , 2003 .