Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4
暂无分享,去创建一个
G. Wahl | S. Francoz | M. Maetens | J. Marine | G. Lozano | F. Toledo | M Maetens | G Lozano | J-C Marine | S Francoz | G Wahl | F Toledo | M. Maetens
[1] G. Wahl,et al. The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[2] Lawrence A. Donehower,et al. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 , 1995, Nature.
[3] M. Jackson,et al. MdmX Protects p53 from Mdm2-Mediated Degradation , 2000, Molecular and Cellular Biology.
[4] D. Lane,et al. Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity , 2004, Cell.
[5] R. Honda,et al. Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase , 2000, Oncogene.
[6] Jun Qin,et al. ARF-BP1/Mule Is a Critical Mediator of the ARF Tumor Suppressor , 2005, Cell.
[7] J. Trent,et al. WAF1, a potential mediator of p53 tumor suppression , 1993, Cell.
[8] G. Lozano,et al. Conditional allele of mdm2 which encodes a p53 inhibitor , 2002, Genesis.
[9] D. Livingston,et al. Polyubiquitination of p53 by a Ubiquitin Ligase Activity of p300 , 2003, Science.
[10] A. Levine,et al. A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans , 2004, Cell.
[11] S. Grossman,et al. Yin Yang 1 Is a Negative Regulator of p53 , 2004, Cell.
[12] Hirofumi Tanaka,et al. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 , 1997, FEBS letters.
[13] M. Oren,et al. Mdm2 promotes the rapid degradation of p53 , 1997, Nature.
[14] L. Vassilev,et al. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2 , 2004, Science.
[15] P. Howley,et al. In vivo ubiquitination and proteasome-mediated degradation of p53(1). , 1996, Cancer research.
[16] Stephen N. Jones,et al. Generation of an Mdm2 conditional allele in mice , 2002, Genesis.
[17] Guillermina Lozano,et al. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 , 1995, Nature.
[18] Muyang Li,et al. Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2 , 2003, Science.
[19] Edward Wirth. Logiciel d'analyse de squences d'ADN et de protines , 1996 .
[20] M. McCoy,et al. Flexible lid to the p53-binding domain of human Mdm2: Implications for p53 regulation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[21] Pankaj Oberoi,et al. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells. , 2005, Cancer cell.
[22] Patrick Dowd,et al. The ubiquitin ligase COP1 is a critical negative regulator of p53 , 2004, Nature.
[23] A. Ciechanover,et al. HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[24] Guillermina Lozano,et al. Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation , 2003, Cell.
[25] Stephen N. Jones,et al. Regulation of p53 stability by Mdm2 , 1997, Nature.
[26] J. Niland,et al. The MDM2 gene amplification database. , 1998, Nucleic acids research.
[27] Stephen N. Jones,et al. Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development , 2005, Oncogene.