The effect of multiple scattering on velocity profiles measured using Doppler OCT

We investigate the effect of multiple scattering upon Doppler optical coherence tomography images of model blood vessels immersed in a fluuid with similar optical properties to those of the human dermis. Furthermore, we quantify the deviation of the acquired velocity profiles from that known to exist within the glass capillary at various depths within the scattering media. A flow phantom consisting of a glass tube containing whole blood flowing under laminar conditions submerged in a variable depth of Intralipid was used to simulate a blood vessel within the cutaneous microcirculation. Doppler optical coherence tomography images and velocity profiles of the tube acquired at various depths within the Intralipid are compared to those obtained from the same tube in a non-scattering media with the same refractive index.

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