A molecular mechanism for adrenergic-induced long QT syndrome.

[1]  P. Schwartz,et al.  Long-QT syndrome: from genetics to management. , 2012, Circulation. Arrhythmia and electrophysiology.

[2]  Derick R. Peterson,et al.  Mutations in Cytoplasmic Loops of the KCNQ1 Channel and the Risk of Life-Threatening Events: Implications for Mutation-Specific Response to &bgr;-Blocker Therapy in Type 1 Long-QT Syndrome , 2012, Circulation.

[3]  Viola Lentink,et al.  Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1 , 2012, Circulation research.

[4]  Wataru Shimizu,et al.  Phenotypic manifestations of mutations in genes encoding subunits of cardiac potassium channels. , 2011, Circulation research.

[5]  Yoram Rudy,et al.  Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation , 2011, PLoS Comput. Biol..

[6]  Joseph H. Solomon,et al.  The Morphology of the Rat Vibrissal Array: A Model for Quantifying Spatiotemporal Patterns of Whisker-Object Contact , 2011, PLoS Comput. Biol..

[7]  Jonathan R. Potts,et al.  Animal Interactions and the Emergence of Territoriality , 2011, PLoS Comput. Biol..

[8]  Michael J. Ackerman,et al.  Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals. , 2011, Journal of the American College of Cardiology.

[9]  Dan M. Roden,et al.  Long-QT Syndrome , 2008 .

[10]  A. Moss,et al.  The Common Long-QT Syndrome Mutation KCNQ1/A341V Causes Unusually Severe Clinical Manifestations in Patients With Different Ethnic Backgrounds: Toward a Mutation-Specific Risk Stratification , 2007, Circulation.

[11]  Bba,et al.  Clinical Aspects of Type-1 Long-QT Syndrome by Location, Coding Type, and Biophysical Function of Mutations Involving the KCNQ1 Gene , 2007, Circulation.

[12]  R. Virmani,et al.  Identification of novel missense mutations of cardiac ryanodine receptor gene in exercise-induced sudden death at autopsy. , 2006, The Journal of molecular diagnostics : JMD.

[13]  S. Priori,et al.  Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice. , 2005, JAMA.

[14]  László Virág,et al.  Restricting Excessive Cardiac Action Potential and QT Prolongation: A Vital Role for IKs in Human Ventricular Muscle , 2005, Circulation.

[15]  B. Balkau,et al.  New KCNQ1 mutations leading to haploinsufficiency in a general population; Defective trafficking of a KvLQT1 mutant. , 2004, Cardiovascular research.

[16]  Carlo Napolitano,et al.  Risk stratification in the long-QT syndrome. , 2003, The New England journal of medicine.

[17]  P. Szafranski,et al.  KCNQ1 mutations in patients with a family history of lethal cardiac arrhythmias and sudden death , 2003, Clinical genetics.

[18]  W. Shimizu,et al.  Exercise Stress Test Amplifies Genotype-Phenotype Correlation in the LQT1 and LQT2 Forms of the Long-QT Syndrome , 2003, Circulation.

[19]  R. Kass,et al.  Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[20]  Junko Kurokawa,et al.  Requirement of a Macromolecular Signaling Complex for β Adrenergic Receptor Modulation of the KCNQ1-KCNE1 Potassium Channel , 2002, Science.

[21]  A. Kobori,et al.  Characterization and subcellular localization of KCNQ1 with a heterozygous mutation in the C terminus. , 2001, Journal of molecular and cellular cardiology.

[22]  M. Sanguinetti,et al.  Long QT Syndrome: , 2000, Journal of cardiovascular electrophysiology.

[23]  D. Tester,et al.  Swimming, a gene-specific arrhythmogenic trigger for inherited long QT syndrome. , 1999, Mayo Clinic proceedings.

[24]  S. Priori,et al.  The long QT syndrome. , 1997, Current problems in cardiology.

[25]  M. Sanguinetti,et al.  Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel , 1996, Nature.

[26]  T. Mcdonald,et al.  Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. , 1994, Physiological reviews.

[27]  G. Breithardt,et al.  Life-threatening Arrhythmias Genotype-phenotype Correlation in the Long-qt Syndrome : Gene-specific Triggers for Genotype-phenotype Correlation in the Long-qt Syndrome Gene-specific Triggers for Life-threatening Arrhythmias , 2022 .